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北京大学 [4]
山东大学 [3]
吉林大学白求恩第一医... [3]
厦门大学 [2]
复旦大学上海医学院 [2]
近代物理研究所 [2]
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期刊论文 [19]
其他 [1]
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2020 [1]
2015 [3]
2014 [4]
2013 [2]
2012 [3]
2011 [2]
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Heavy ion radiation-induced DNA damage mediates apoptosis via the Rp127a-Rp15-MDM2-p53/E2F1 signaling pathway in mouse spermatogonia
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 201, 页码: 12
作者:
Li, Hongyan
;
Zhang, Hong
;
Huang, Guomin
;
Dou, Zhihui
;
Xie, Yi
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/01/12
Ionizing radiation
Reproductive toxicology
Ribosomal stress
MDM2-p53 loop
Apoptosis
Identification of PI3K regulatory subunit p55 gamma as a novel inhibitor of vascular smooth muscle cell proliferation and neointimal formation
期刊论文
cardiovascular research, 2015
Li, Geng
;
Xie, Ning
;
Yao, Yuan
;
Zhang, Yan
;
Guo, Jiaojiao
;
Feng, Yuanqing
;
Lv, Fengxiang
;
Xiao, Rui-Ping
;
Cao, Chun-Mei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/13
p55 gamma
Vascular smooth muscle cell proliferation
Neointimal formation
Restenosis
THERAPEUTIC TARGET
CYCLE PROGRESSION
S-PHASE
GROWTH
ARREST
P53
CANCER
P21
3-KINASE
ATHEROSCLEROSIS
Adenovirus siMDM2 and NDRG2 Gene Therapy Inhibits Cell Proliferation and Induces Apoptosis of Squamous Cell Carcinoma
期刊论文
CELL BIOCHEMISTRY AND BIOPHYSICS, 2015, 卷号: 73, 期号: 2, 页码: 513-518
作者:
Wang, Shouzhong
;
Chen, Nan
;
Dong, Na
;
Lu, Leihong
;
Liu, Liqian
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/17
Squamous cell carcinoma
Murine double minute 2
Gene silencing
N-myc
downstream-regulated gene 2
Gene therapy
MicroRNAs in osteosarcoma
期刊论文
Clinica Chimica Acta, 2015, 卷号: 444, 页码: 9-17
作者:
Zhang, Jian
;
Yan, Yi-Guo
;
Wang, Cheng
;
Zhang, Shu-Jun
;
Yu, Xiao-Hua*
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/27
OS
osteosarcoma
miRNAs
microRNAs
CSCs
cancer stem cells
RNA pol
RNA polymerase
DGCR8
DiGeorge syndrome critical gene 8
RISC
RNA-induced silencing complex
Exp 5
exportin 5
Ago
argonaute
MREs
miRNA recognition elements
APE1
apurinic/apyrimidinic endonuclease 1
MDM
murine double minute
TP53
tumor suppressor p53
mTOR
mammalian target of rapamycin
Eag1
ether à go-go 1
PI3K
phosphatidylinositol-3-kinase
PTEN
phosphatase and tensin homolog deleted on chromosome ten
Hsp90B1
heat shock protein 90B1
BMP2
bone morphogenetic protein 2
IGF1R
insulin-like growth factor 1 receptor
FAK
phospho-Akt and focal adhesion kinase
LPAATβ
lysophosphatidic acid acyltransferase β
HMGB1
high-mobility group box 1
FASN
fatty acid synthase
LZTS1
leucine zipper putative tumor suppressor 1
MMP
matrix metalloproteinase
LNA
locked nucleic acid
DATS
diallyl trisulfide
miRNAs
OS
TP53
Notch
Chemoresistance
MdmX在Axin-p53信号通路中的调控机制
期刊论文
2014
贺颖
;
叶志云
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2016/05/17
鼠双微体基因X(MdmX)
Axin
p53
Mouse double minute X(MdmX)
Axin
p53
Murine Double Minute 2 siRNA and wild-type p53 gene therapy interact positively with zinc on prostate tumours in vitro and in vivo
期刊论文
EUROPEAN JOURNAL OF CANCER, 2014, 卷号: 50, 期号: 6
作者:
Wang, Bo
;
Gu, Junlian
;
Liu, Yanan
;
Zhong, Lingzhi
;
Tang, Yufeng
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Prostate cancer
Zinc
P53 tumour suppressor
MDM2
Gene therapy
Murine double minute 2 siRNA and wild-type p53 gene therapy enhances sensitivity of the SKOV3/DDP ovarian cancer cell line to cisplatin chemotherapy in vitro and in vivo
期刊论文
CANCER LETTERS, 2014, 卷号: 343, 期号: 2
作者:
Wang, Bo
;
Gu, Junlian
;
Tang, Yufeng
;
Liu, Yanan
;
Guo, Hua
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
SKOV3/DDP
Drug resistance
Cisplatin
P53
Si-mdm2
hCINAP is a novel regulator of ribosomal protein-HDM2-p53 pathway by controlling NEDDylation of ribosomal protein S14
期刊论文
oncogene, 2014
Zhang, J.
;
Bai, D.
;
Ma, X.
;
Guan, J.
;
Zheng, X.
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/11/14
hCINAP
RPS14
NEDDylation
HDM2
p53
SACCHAROMYCES-CEREVISIAE
ADENYLATE KINASE
P53
MDM2
INHIBITION
HDM2
L11
IDENTIFICATION
DEGRADATION
ACTIVATION
鼠双微粒体-2基因沉默对人肝癌HepG2细胞移植瘤生长的抑制作用
期刊论文
中华肝脏病杂志, 2013, 卷号: 21, 期号: 3
作者:
赵燕颖[1]李亚刚[1]孙远杰[1]刘海鹏[2]杨泽成[3]张舵舵[2]赵春燕[4]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
癌,肝细胞
基因沉默
RNA,小分子干扰
基因,p53
鼠双微粒体-2基因
Carcinoma,hepatocellular
Gene silencing
RNA,small interfering
Genes,p53
Murine double minute 2
Diverse Mechanisms of Somatic Structural Variations in Human Cancer Genomes
其他
2013-01-01
Yang, Lixing
;
Luquette, Lovelace J.
;
Gehlenborg, Nils
;
Xi, Ruibin
;
Haseley, Psalm S.
;
Hsieh, Chih-Heng
;
Zhang, Chengsheng
;
Ren, Xiaojia
;
Protopopov, Alexei
;
Chin, Lynda
;
Kucherlapati, Raju
;
Lee, Charles
;
Park, Peter J.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/11
DOUBLE-STRAND BREAKS
DOUBLE-MINUTE CHROMOSOMES
MAMMALIAN-CELLS
PROSTATE-CANCER
COPY NUMBER
REARRANGEMENTS
GENE
SEQUENCES
PATTERNS
MUTATION
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