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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Acetaldehyde induces similar cytotoxic and genotoxic risks in BEAS-2B cells and HHSteCs: involvement of differential regulation of MAPK/ERK and PI3K/AKT pathways
期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 卷号: 30
作者:
Zhang, Jingni
;
Wang, Hongjuan
;
Chen, Huan
;
Liu, Yong
;
Wang, An
收藏
  |  
浏览/下载:150/0
  |  
提交时间:2023/11/17
Acetaldehyde
Cytotoxicity
Genotoxicity
BEAS-2B cells
HHSteCs
MAPK/ERK
PI3K/AKT
Oyster studies reveal the duplication and functional diversification of Bivalvia caspase-8 genes
期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2023, 页码: 13
作者:
Deng, Shaoxi
;
Qu, Tao
;
Zhang, Guofan
;
Xu, Fei
收藏
  |  
浏览/下载:111/0
  |  
提交时间:2023/12/07
caspase-8
apoptosis
metamorphosis
inflammation
Crassostrea gigas
Defective EMC1 drives abnormal retinal angiogenesis via Wnt/b-catenin signaling and may be associated with the pathogenesis of familial exudative vitreoretinopathy
期刊论文
GENES & DISEASES, 2023, 卷号: 10, 期号: 6, 页码: 2572
作者:
Li, Shujin
;
Yang, Mu
;
Zhao, Rulian
;
Peng, Li
;
Liu, Wenjing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/01
Gefitinib enhances the anti-tumor immune response against EGFR-mutated NSCLC by upregulating B7H5 expression and activating T cells via CD28H
期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2022, 卷号: 61
作者:
Guo, Huihui
;
Zhang, Xilin
;
Xie, Shangzhi
;
Chen, Tianwei
;
Xie, Dong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/22
gefitinib
CD28H
NSCLC
EGFR mutation
Transcriptome Analysis Provides Insights into Copulation, Fertilization, and Gestation in Sebastes schlegelii
期刊论文
GENES, 2022, 卷号: 13, 期号: 10, 页码: 15
作者:
Wang, Xueying
;
Zhao, Ning
;
Wang, Tao
;
Du, Shuran
;
Liu, Qinghua
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/01/04
S
schlegelii
copulation
fertilization
embryogenesis
RNA-seq
Associations Between Serum Reproductive Hormone Concentrations and Hormonal Receptor Status Among Postmenopausal Chinese Women With Breast Cancer: An Observational Study
期刊论文
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12
作者:
Jiang, Chuner
;
Wu, Peng
;
He, Xiangming
;
Ni, Jianfen
;
Ding, Xiaowen
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/12/23
breast cancer
postmenopausal
reproductive hormones
estrogen receptor
progesterone receptor
HER2 receptor
Deep learning for predicting immunotherapeutic efficacy in advanced non-small cell lung cancer patients: a retrospective study combining progression-free survival risk and overall survival risk
期刊论文
TRANSLATIONAL LUNG CANCER RESEARCH, 2022, 页码: 23
作者:
He, Bing-Xi
;
Zhong, Yi-Fan
;
Zhu, Yong-Bei
;
Deng, Jia-Jun
;
Fang, Meng-Jie
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/06/10
Tumor biomarkers
immunotherapy
lung neoplasms
programmed cell death 1 receptor (PD-1 receptor)
biostatistics
HER2 exon 20 insertion mutations in lung adenocarcinoma with leptomeningeal metastasis: a case report and response to poziotinib
期刊论文
ANNALS OF PALLIATIVE MEDICINE, 2022, 卷号: 11
作者:
Fan, Ying
;
Qin, Jing
;
Han, Na
;
Lu, Hongyang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/23
Leptomeningeal metastasis (LM)
cerebrospinal fluid
HER2 exon 20 insertion mutations
poziotinib
case report
Enzalutamide-induced and PTH1R-mediated TGFBR2 degradation in osteoblasts confers resistance in prostate cancer bone metastases
期刊论文
CANCER LETTERS, 2022, 卷号: 525, 页码: 170-178
作者:
Su, Shang
;
Cao, Jingchen
;
Meng, Xiangqi
;
Liu, Ruihua
;
Vander Ark, Alexandra
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2022/01/04
Enzalutamide resistance
Prostate cancer
Bone microenvironment
TGFBR2
PTH1R
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