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科研机构
上海药物研究所 [10]
合肥物质科学研究院 [9]
厦门大学 [5]
上海生物化学与细胞生... [5]
中国医学科学院 北京... [5]
深圳先进技术研究院 [2]
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期刊论文 [44]
会议论文 [1]
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2022 [2]
2021 [6]
2020 [3]
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2018 [3]
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Oncology [3]
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The Clinical Research and Latest Application of Genomic Assays in Early-Stage Breast Cancer
期刊论文
TECHNOLOGY IN CANCER RESEARCH & TREATMENT, 2022, 卷号: 21
作者:
Chen, Keyu
;
Wu, Jiayi
;
Fang, Ziru
;
Shao, Xiying
;
Wang, Xiaojia
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/22
early-stage breast cancer
genomic expression profiles
Oncotype DX
MammaPrint
RecurIndex
prediction tools
A molecular approach integrating genomic and DNA methylation profiling for tissue of origin identification in lung-specific cancer of unknown primary
期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2022, 卷号: 20
作者:
Chen, Kaiyan
;
Zhang, Fanrong
;
Yu, Xiaoqing
;
Huang, Zhiyu
;
Gong, Lei
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/05/16
Cancer with unknown primary (CUP)
Multiple primary tumor
Comprehensive genomic profiling (CGP)
DNA methylation
Machine learning
Lung cancer
Integrated genomic and DNA methylation analysis of patients with advanced non-small cell lung cancer with brain metastases
期刊论文
MOLECULAR BRAIN, 2021, 卷号: 14
作者:
Xu, Yanjun
;
Huang, Zhiyu
;
Yu, Xiaoqing
;
Chen, Kaiyan
;
Fan, Yun
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/01/25
Brain metastases
Predictive biomarker
DNA methylation
Somatic mutation
Advanced non-small cell lung cancer (advanced NSCLC)
Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:
Tao, Zhonghua
;
Liu, Jianxia
;
Li, Ting
;
Xu, Hong
;
Chen, Kai
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/01/10
receptor tyrosine kinase
gene fusion
genomic rearrangments
breast cancer
next-generation sequencing
Additive effects of variants of unknown significance in replication repair-associated DNA polymerase genes on mutational burden and prognosis across diverse cancers
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 卷号: 9
作者:
Ying, Jieer
;
Yang, Lin
;
Yin, Jiani C.
;
Xia, Guojie
;
Xing, Minyan
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/11/15
biomarkers
tumor
genetic markers
genome instability
Immunotherapy
translational medical research
High chromosome instability identified by low-pass whole-genome sequencing assay is associated with TP53 copy loss and worse prognosis in BRCA1 germline mutation breast cancer
期刊论文
BREAST CANCER, 2021
作者:
Zhu, Liang
;
Pan, Jia-Ni
;
Qian, Ziliang
;
Ye, Wei-Wu
;
Wang, Xiao-Jia
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/09/06
CIN
TP53
BRCA1
LPWGS
Breast cancer
Combination of GC-MS based metabolomics analysis with mouse xenograft models reveals a panel of dysregulated circulating metabolites and potential therapeutic targets for colorectal cancer
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2021, 卷号: 10
作者:
Ni, Juan
;
Chen, Yang
;
Li, Ningning
;
Sun, Diandian
;
Ju, Haixing
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/06/15
Gas chromatography-mass spectrometry (GC-MS)
metabolomics
colorectal cancer (CRC)
amino acid transporter
PI3K alpha inhibitor CYH33 triggers antitumor immunity in murine breast cancer by activating CD8(+)T cells and promoting fatty acid metabolism
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 卷号: 9, 期号: 8, 页码: 16
作者:
Sun, Pu
;
Zhang, Xi
;
Wang, Rong-Jing
;
Ma, Qing-Yang
;
Xu, Lan
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/11/04
tumor microenvironment
immunomodulation
immunologic memory
lymphocytes
tumor-infiltrating
macrophages
Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein
期刊论文
ONCOGENE, 2020, 页码: 14
作者:
Qian, Wenli
;
Li, Qi
;
Wu, Xinglong
;
Li, Wenguo
;
Li, Qiwei
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/12/21
Osimertinib successfully combats EGFR-negative glioblastoma cells by inhibiting the MAPK pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:
Chen, Cheng
;
Cheng, Chuan-dong
;
Wu, Hong
;
Wang, Zuo-wei
;
Wang, Li
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/11/26
glioblastoma
osimertinib
temozolamide
MAPK-signaling pathway
MNK
eukaryotic translation initiation factor 4E
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