QQ客服 官方微博 反馈留言

浏览/检索结果: 共12条，第1-10条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Novel bivalent BET inhibitor N2817 exhibits potent anticancer activity and inhibits TAF1 期刊论文 BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 185, 页码: 14 作者:  Wu, Qian;  Chen, Dan-Qi;  Sun, Lin;  Huan, Xia-Juan;  Bao, Xu-Bin 收藏  |  浏览/下载：116/0  |  提交时间：2021/05/24 N2817  Bivalent BET inhibitors  Monovalent BET inhibitors  TAF1  Anticancer activity   A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction 期刊论文 INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713 作者:  Damaneh, Mohammadali Soleimani;  Hu, Jian-Ping;  Huan, Xia-Juan;  Song, Shan-Shan;  Tian, Chang-Qing 收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01 BET inhibitor  Cell proliferation  Apoptosis  Anti-cancer agent   Discovery of 8-Methyl-pyrrolo[1,2-a]pyrazin-1(2H)-one Derivatives as Highly Potent and Selective Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitors 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 3956-3975 作者:  Li, Zizhou;  Xiao, Senhao;  Yang, Yaxi;  Chen, Chao;  Lu, Tian 收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01 A patent review of BRD4 inhibitors (2013-2019) 期刊论文 EXPERT OPINION ON THERAPEUTIC PATENTS, 2020, 卷号: 30, 期号: 1, 页码: 57-81 作者:  Lu, Tian;  Lu, Wenchao;  Luo, Cheng 收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 Bromodomain-containing protein 4 (BRD4)  bromodomain and extra-terminal (BET) family  small molecule inhibitors  cancer  patent  therapeutic potential   Structure-Based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 18, 页码: 8642-8663 作者:  Hu, Jianping;  Tian, Chang-Qing;  Damaneh, Mohammadali Soleimani;  Li, Yanlian;  Cao, Danyan 收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01 Inhibition of the BET family reduces its new target gene IDO1 expression and the production of L-kynurenine 期刊论文 CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 13 作者:  Tian, Chang-Qing;  Chen, Lin;  Chen, Hua-Dong;  Huan, Xia-Juan;  Hu, Jian-Ping 收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01 Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 15, 页码: 6685-6704 作者:  Qin, Chong;  Hu, Yang;  Zhou, Bing;  Fernandez-Salas, Ester;  Yang, Chao-Yie 收藏  |  浏览/下载：45/0  |  提交时间：2019/01/08 Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 14, 页码: 6110-6120 作者:  Zhao, Yujun;  Zhou, Bing;  Bai, Longchuan;  Liu, Liu;  Yang, Chao-Yie 收藏  |  浏览/下载：49/0  |  提交时间：2019/01/08 Design, synthesis and biological evaluation of benzo[cd]indo1-2(1H)-ones derivatives as BRD4 inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 264-273 作者:  Feng, Yuxin;  Xiao, Senhao;  Chen, Yantao;  Jiang, Hao;  Liu, Na 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Benzo[cd]indol-2(1H)-one  Sulfonamide  BRD4 inhibitor  Bromodomain and extra-terminal domain  Acetyl-lysine binding pocket   Y08060: A Selective BET Inhibitor for Treatment of Prostate Cancer 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 3, 页码: 262-267 作者:  Xiang, Quping;  Zhang, Yan;  Li, Jiaguo;  Xue, Xiaoqian;  Wang, Chao 收藏  |  浏览/下载：42/0  |  提交时间：2019/06/20 Bromodomain  Brd4  Prostate Cancer  Epigenetics