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Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo
期刊论文
CHEMISTRY & BIODIVERSITY, 2024, 页码: 11
作者:
Sun, Hao
;
Bai, Xiaoyi
;
Zhang, Yiting
;
Gao, Yanan
;
Dai, Jiajia
收藏
  |  
浏览/下载:0/0
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提交时间:2024/06/04
Anti-tumor
SHP2
Orthosteric inhibitor
Apoptosis
Bromophenol
A Novel Bifunctional Alginate Lyase and Antioxidant Activity of the Enzymatic Hydrolysates
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2024, 卷号: 72, 期号: 8, 页码: 4116-4126
作者:
Gu, Xiaoqian
;
Fu, Liping
;
Wang, Zhiyan
;
Cao, Zhe
;
Zhao, Luying
收藏
  |  
浏览/下载:118/0
  |  
提交时间:2024/04/07
bifunctional alginatelyase
alginate oligosaccharides
antioxidant activity
Multi-treatments based on polydimethylsiloxane and metal-organic framework wrapped with graphene oxide for achieving long-term corrosion and fouling protection: experimental and density functional theory aspects
期刊论文
CONSTRUCTION AND BUILDING MATERIALS, 2023, 卷号: 384, 页码: 14
作者:
Zhou, Ziyang
;
Seif, Abdolvahab
;
Pourhashem, Sepideh
;
Duan, Jizhou
;
Rashidi, Alimorad
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  |  
浏览/下载:5/0
  |  
提交时间:2023/12/07
Graphene oxide
Metal-organic frameworks
Nanohybrids
Corrosion resistance
Density functional theory
Discovery of a novel jellyfish venom metalloproteinase inhibitor from secondary metabolites isolated from jellyfish-derived fungus Aspergillus versicolor SmT07
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 卷号: 365, 页码: 8
作者:
Yue, Yang
;
Yu, Huahua
;
Suo, Qishan
;
Li, Rongfeng
;
Liu, Song
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  |  
浏览/下载:15/0
  |  
提交时间:2023/01/04
Nemopilema nomurai
Jellyfish envenomations
Aspergillus versicolor
Metalloproteinase inhibitors
Molecular docking
Binding Pattern Reconstructions of FGF-FGFR Budding-Inducing Signaling in Reef-Building Corals
期刊论文
FRONTIERS IN PHYSIOLOGY, 2022, 卷号: 12, 页码: 12
作者:
Guo, Zhuojun
;
Liao, Xin
;
Chen, J. -Y.(陈均远)
;
He, Chunpeng
;
Lu, Zuhong
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  |  
浏览/下载:28/0
  |  
提交时间:2022/02/24
reef-building coral
budding reproduction
receptor tyrosine kinase
full-length transcriptome
FGF-FGFR binding models
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:
Meng, Xiang-Dong
;
Gao, Li-Xin
;
Wang, Zhi-Jia
;
Feng, Bo
;
Zhang, Chun
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  |  
浏览/下载:31/0
  |  
提交时间:2021/12/01
2,5-diphenyl-1,3,4-oxadiazole derivatives
SHP2
Inhibitors
Structure-activity relationships (SAR)
Synthesis of the analogs of plocabulin and their preliminary structure-activity relationship study
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 51, 页码: 5
作者:
Wang, Leiming
;
Li, Xin
;
Cui, Hong
;
Lei, Xinsheng
;
Liu, Hongchun
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/01
Marine nature products
Plocabulin
PM060184
Synthesis
Antiproliferation
TANK-binding kinase 1 (TBK1): An emerging therapeutic target for drug discovery
期刊论文
DRUG DISCOVERY TODAY, 2021, 卷号: 26, 期号: 10, 页码: 2445-2455
作者:
Xiang, Shuang
;
Song, Shukai
;
Tang, Haotian
;
Smaill, Jeff B.
;
Wang, Aiqun
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/12/01
Antibiotic resistance
Computational biology
Databases
In silico tools
Structural insights into ligand recognition and activation of the melanocortin-4 receptor
期刊论文
CELL RESEARCH, 2021, 页码: 13
作者:
Zhang, Huibing
;
Chen, Li-Nan
;
Yang, Dehua
;
Mao, Chunyou
;
Shen, Qingya
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/11/04
Silver nanoparticles protect against arsenic induced genotoxicity via attenuating arsenic bioaccumulation and elevating antioxidation in mammalian cells
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2021, 卷号: 413
作者:
Wang, Xue
;
Nie, Yaguang
;
Si, Bo
;
Wang, Tong
;
Hei, Tom K.
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  |  
浏览/下载:94/0
  |  
提交时间:2021/06/15
Arsenic (As)
Silver nanoparticles (AgNPs)
Detoxification
Bioaccumulation
Antioxidation
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