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上海药物研究所 [15]
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期刊论文 [29]
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Hepatocyte peroxisome proliferator-activated receptor alpha regulates bile acid synthesis and transport
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2019, 期号: 10, 页码: 1396-1411
作者:
Xie, Cen
;
Takahashi, Shogo
;
Brocker, Chad N.
;
He, Shijun
;
Chen, Li
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Peroxisome proliferator-activated receptor alpha
Wy-14,643
Bile acid homeostasis
Farnesoid X receptor
Metabolomics
Emodin Rescues Intrahepatic Cholestasis via Stimulating FXR/BSEP Pathway in Promoting the Canalicular Export of Accumulated Bile
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10
作者:
Xiong, Xiao-Li
;
Ding, Yan
;
Chen, Zhi-Lin
;
Wang, Yao
;
Liu, Pan
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/12/05
emodin
cholestasis
bile salt export pump
signaling pathway
upregulation
downregulation
Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503
作者:
Dong, Jiajia
;
Olaleye, Olajide E.
;
Jiang, Rongrong
;
Li, Jing
;
Lu, Chuang
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
Dysregulation of BSEP and MRP2 May Play an Important Role in Isoniazid-Induced Liver Injury via the SIRT1/FXR Pathway in Rats and HepG2 Cells
期刊论文
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2018, 卷号: 41, 期号: 8
作者:
Gao, Huan
;
Song, Yanqing
;
Tao, Lina
;
Zhai, Jinghui
;
Zhang, Sixi
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/05
isoniazid
liver injury
bile salt export pump
multidrug resistance protein 2
farnesoid X receptor
Sirtuin 1
Comprehensive bile acid profiling in hereditary intrahepatic cholestasis: Genetic and clinical correlations
期刊论文
LIVER INTERNATIONAL, 2018, 卷号: 38, 期号: 9
作者:
Liu, Teng
;
Wang, Ren-Xue
;
Han, Jun
;
Hao, Chen-Zhi
;
Qiu, Yi-Ling
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
ABCB11
bile salt export pump
liquid chromatography-mass spectrometry
PFIC2
[Relationship between phenotype and genotype of ABCB11 deficiency in siblings and literature review].
期刊论文
Zhonghua er ke za zhi = Chinese journal of pediatrics, 2018, 卷号: 56, 期号: 6
作者:
Peng X R
;
Lu Y
;
Zhang M H
;
Li L T
;
Xie X B
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
ABCB11 gene
Bile salt export pump
Child
Cholestasis, intrahepatic
PPAR alpha activation protects against cholestatic liver injury
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 9967
作者:
Zhao, Qi
;
Yang, Rui
;
Wang, Jing
;
Hu, Dan-Dan
;
Li, Fei
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2017/10/23
Primary Biliary-cirrhosis
Bile-acid Homeostasis
Receptor-alpha
Ursodeoxycholic Acid
Cholesterol 7-alpha-hydroxylase
Beta-oxidation
Fenofibrate
Therapy
Mice
Hepatotoxicity
Nimesulide and 4 '-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis
期刊论文
DRUG METABOLISM AND DISPOSITION, 2017, 卷号: 45, 期号: 5, 页码: 441-448
作者:
Zhou, Lei
;
Pang, Xiaoyan
;
Jiang, Jingfang
;
Zhong, Dafang
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
The in silico identification of human bile salt export pump (ABCB11) inhibitors associated with cholestatic drug-induced liver injury
期刊论文
MOLECULAR BIOSYSTEMS, 2017, 卷号: 13, 期号: 2, 页码: 417-424
作者:
Xi, LL
;
Yao, J
;
Wei, YH
;
Wu, XA
;
Yao, XJ
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/05/08
The role of Ntcp, Oatp2, Bsep and Mrp2 in liver injury induced by Dioscorea bulbifera L. and Diosbulbin B in mice
期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2017, 卷号: 51
作者:
Qu, Xiao-Yu
;
Tao, Li-Na
;
Zhang, Si-Xi
;
Sun, Jing-Meng
;
Niu, Jun-Qi
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
Dioscorea bulbifera L.
Diosbulbin B
Na plus -taurocholate co-transporting polypeptide
Organic anion transporting polypeptide 2
Bile salt export pump
Multidrug resistance associated protein 2
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