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CORC

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Development of Taccalonolide AJ-Hydroxypropyl-beta-Cyclodextrin Inclusion Complexes for Treatment of Clear Cell Renal-Cell Carcinoma 期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 23, 页码: 14
作者:  Han, Jing;  Zhang, Siwang;  Niu, Junxin;  Zhang, Chunli;  Dai, Weichen
收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24
Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10
作者:  Zhang, Yu;  Goto, Masuo;  Oda, Akifumi;  Hsu, Pei-Ling;  Guo, Ling-Li
收藏  |  浏览/下载：67/0  |  提交时间：2019/07/29
Discover 4 beta-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 170, 页码: 73-86
作者:  Zhao, Wei;  He, Long;  Xiang, Tian-Le;  Tang, Ya-Jie
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/11
The Structure of MT189-Tubulin Complex Provides Insights into Drug Design 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 9, 页码: 1069-1073
作者:  Li, Zhongping;  Ma, Lingling;  Wu, Chengyong;  Meng, Tao;  Ma, Lanping
收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 817-842
作者:  Zhou, Pengfei;  Liang, Yuru;  Zhang, Hao;  Jiang, Hao;  Feng, Kechang
收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08
The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in beta-tubulin 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: Vol.293 No.24, 页码: 9461-9472
作者:  Yang, JH;  Yan, W;  Yu, YM;  Wang, YX;  Yang, T
收藏  |  浏览/下载：4/0  |  提交时间：2019/02/25
Potent Antitumor Activities and Structure Basis of the Chiral beta-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 22, 页码: 10329-10334
作者:  Zhou, Pengfei;  Liu, Yan;  Zhou, Lu;  Zhu, Kongkai;  Feng, Kechang
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08
Potent Antitumor Activities and Structure Basis of the Chiral beta-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 22
作者:  Zhou, Pengfei;  Liu, Yan;  Zhou, Lu;  Zhu, Kongkai;  Feng, Kechang
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/05
A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule 期刊论文
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 2, 页码: 261-270
作者:  Liu, Zu-long;  Tian, Wei;  Wang, Yong;  Kuang, Shan;  Luo, Xiao-min
收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08
Structural insight into the mechanism of epothilone A bound to beta-tubulin and its mutants at Arg282Gln and Thr274Ile 期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2012, 卷号: 30, 期号: 5, 页码: 559-573
作者:  Shi, Guojun;  Wang, Yue;  Jin, Yi;  Chi, Shaoming;  Shi, Qiang
收藏  |  浏览/下载：15/0  |  提交时间：2019/04/09

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