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Association between ADAMTS-4 gene polymorphism and lumbar disc degeneration in Chinese Han population 期刊论文
2016, 卷号: 34, 期号: 5, 页码: 860-864
作者:  Liu, Sen;  Wu, Nan;  Liu, Jiaqi;  Liu, Hao;  Su, Xinlin
收藏  |  浏览/下载:26/0  |  提交时间:2020/01/04
Interleukin-1β in intervertebral disk degeneration 期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 262-272
作者:  Yang, Wei;  Yu, Xiao-Hua;  Wang, Cheng;  He, Wen-Si;  Zhang, Shu-Jun
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/27
IDD  intervertebral disk degeneration  IL-1  interleukin-1  IVD  intervertebral disk  ECM  extracellular matrix  LBP  low back pain  MMPs  matrix metalloproteinases  NP  nucleus pulposus  AF  annulus fibrosus  Col II  type II collagen  Col I  type I collagen  NTP  N-terminal peptide  NLS  nuclear localization sequence  IL-1RII  IL-1 receptor type II  TLRs  Toll-like receptors  IL-1RI  IL-1 receptor type I  IL-1RAcP  IL-1 receptor accessory protein  TIR  Toll-like/IL-1 receptor  MyD88  myeloid differentiation factor 88  TNF  tumor necrosis factor  NF-κB  nuclear factor-kappa B  MAPK  mitogen-activated protein kinase  IL-1Ra  IL-1 receptor antagonist  IFN-γ  interferon-γ  CCL  CC chemokine ligand  CXCL  CX chemokine ligand  ADAMTSs  a disintegrin and metalloprotease with thrombospondin motifs  TIMPs  tissues inhibitors of metalloproteinases  VEGF  vascular endothelial growth factor  NGF  nerve growth factor  BDNF  brain-derived neurotrophic factor  ROS  reactive oxygen species  SOD  superoxide dismutase  CAT  catalase  miRNAs  microRNAs  MSCs  mesenchymal stem cells  PRP  platelet-rich plasma  IL-1  IDD  Inflammatory responses  Angiogenesis  Apoptosis  
MMPs and ADAMTSs in intervertebral disc degeneration 期刊论文
Clinica Chimica Acta, 2015, 卷号: 448, 页码: 238-246
作者:  Wang, Wen-Jun*;  Yu, Xiao-Hua;  Wang, Cheng;  Yang, Wei;  He, Wen-Si
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/27
IVD  intervertebral disc  IDD  intervertebral disc degeneration  ECM  extracellular matrix  MMPs  matrix metalloproteinases  ADAMTSs  a disintegrin and metalloprotease with thrombospondin motifs  NP  nucleus pulposus  AF  annulus fibrosus  Col I  type I collagen  Col II  type II collagen  IL-1  interleukin-1  MAPK  mitogen-activated protein kinase  MRI  magnetic resonance imaging  TIMP  tissue inhibitor of metalloproteinase  NGF  nerve growth factor  BMP  bone morphogenetic protein  TGF-β1  transforming growth factor-β1  SNPs  single nucleotide polymorphisms, miRNAs, microRNAs  LPS  lipopolysaccharide  TNF-α  tumor necrosis factor-α  NF-κB  nuclear factor κB  NO  nitric oxide  SDC4  syndecan-4  RSV  resveratrol  LfcinB  bovine lactoferricin  HO-1  heme oxygenase-1  MSCs  mesenchymal stem cells  IDD  MMPs  ADAMTSs  Col II  Aggrecan  
Interleukin-1β in intervertebral disk degeneration 期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 262-272
作者:  WeiYang;  Xiao-HuaYu
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/27
IDD  intervertebral disk degeneration  IL-1  interleukin-1  IVD  intervertebral disk  ECM  extracellular matrix  LBP  low back pain  MMPs  matrix metalloproteinases  NP  nucleus pulposus  AF  annulus fibrosus  Col II  type II collagen  Col I  type I collagen  NTP  N-terminal peptide  NLS  nuclear localization sequence  IL-1RII  IL-1 receptor type II  TLRs  Toll-like receptors  IL-1RI  IL-1 receptor type I  IL-1RAcP  IL-1 receptor accessory protein  TIR  Toll-like/IL-1 receptor  MyD88  myeloid differentiation factor 88  TNF  tumor necrosis factor  NF-κB  nuclear factor-kappa B  MAPK  mitogen-activated protein kinase  IL-1Ra  IL-1 receptor antagonist  IFN-γ  interferon-γ  CCL  CC chemokine ligand  CXCL  CX chemokine ligand  ADAMTSs  a disintegrin and metalloprotease with thrombospondin motifs  TIMPs  tissues inhibitors of metalloproteinases  VEGF  vascular endothelial growth factor  NGF  nerve growth factor  BDNF  brain-derived neurotrophic factor  ROS  reactive oxygen species  SOD  superoxide dismutase  CAT  catalase  miRNAs  microRNAs  MSCs  mesenchymal stem cells  PRP  platelet-rich plasma  IL-1  IDD  Inflammatory responses  Angiogenesis  Apoptosis  
MicroRNAs: New players in intervertebral disc degeneration 期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 333-341
作者:  Wang, Cheng;  Wang, Wen-Jun;  Yan, Yi-Guo;  Xiang, Yong-Xiao;  Zhang, Jian
收藏  |  浏览/下载:22/0  |  提交时间:2019/12/27
IVD  intervertebral disc  NP  nucleus pulposus  AF  annulus fibrosus  CEPs  cartilaginous endplates  IDD  intervertebral disc degeneration  ECM  extracellular matrix  miRNAs  microRNAs  RNA pol  RNA polymerase  DGCR8  DiGeorge syndrome critical gene 8  Exp 5  exportin 5  TRBP  transactivating response RNA-binding protein  RISC  RNA-induced silencing complex  Ago  Argonaute  PI3K  phosphoinositide 3-kinase  MAPK  mitogen-activated protein kinase  TGF-β  transforming growth factor-β  PDGF  platelet-derived growth factor  IGF  insulin-like growth factor  EGF  epidermal growth factor  CDKI1B  cyclin-dependent kinase inhibitor 1B  TNF-α  tumor necrosis factor-α  FADD  Fas-associated death domain-containing protein  Col II  type II collagen  Col I  type I collagen  MMPs  matrix metalloproteinases  ADAMTSs  a disintegrin and metalloprotease with thrombospondin motifs  Col I  type I collagen  Col II  type II collagen  FGF2  fibroblast growth factor 2  FGFR  fibroblast growth factor receptor  IL-1β  interleukin-1β  NGF  nerve growth factor  HOXD10  homeobox D10  MiRNAs  IDD  NP cells  Apoptosis  Cell proliferation  


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