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科研机构
山东大学 [9]
内容类型
期刊论文 [9]
发表日期
2019 [1]
2018 [1]
2017 [6]
2016 [1]
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Novel urate transporter 1 (URAT1) inhibitors: a review of recent patent literature (2016?2019)
期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2019, 卷号: 29, 期号: 11, 页码: 871-879
作者:
Dong, Yue
;
Zhao, Tong
;
Ai, Wei
;
Zalloum, Waleed A.
;
Kang, Dongwei
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
URAT1 inhibitors
lesinurad
RDEA3170
SHR4640
benzbromarone
sulfonamide
dual inhibitor
gout
hyperuricemia
Systematic Structure-Activity Relationship (SAR) Exploration of Diarylmethane Backbone and Discovery of A Highly Potent Novel Uric Acid Transporter 1 (URAT1) Inhibitor
期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 2
作者:
Cai, Wenqing
;
Wu, Jingwei
;
Liu, Wei
;
Xie, Yafei
;
Liu, Yuqiang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/11
gout
hyperuricemia
URAT1 inhibitor
lesinurad
structure-activity
relationship (SAR)
synthesis
Synthesis, Crystal Structure and URAT1 Inhibitory Activity of 2-((5-Bromo-4-((4-cyclobutylnaphth-1-yl)methyl)-4H-1,2,4-triazol-3-yl)th io)acetic Acid
期刊论文
结构化学, 2017, 卷号: 36, 期号: 9, 页码: 1425-1432
作者:
Zhang Xiansheng
;
Xin Xiao
;
Liu Wei
;
Xie Yafei
;
Liu Changying
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/16
synthesis
crystal structure
URAT1 inhibitor
lesinurad
Discovery of Flexible Naphthyltriazolylmethane-based Thioacetic Acids as Highly Active Uric Acid Transporter 1 (URAT1) Inhibitors for the Treatment of Hyperuricemia of Gout
期刊论文
MEDICINAL CHEMISTRY, 2017, 卷号: 13, 期号: 3, 页码: 260-281
作者:
Zhang, Xiansheng
;
Wu, Jingwei
;
Liu, Wei
;
Liu, Yuqiang
;
Xie, Yafei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/12
Gout
hyperuricemia
URAT1 inhibitor
lesinurad
flexible
synthesis
Synthesis,Crystal Structure and URAT1 Inhibitory Activity of 2-((5-Bromo-4-((4-cyclobutylnaphth-1-yl)methyl)-4H-1,2,4-triazol-3-yl)thio)acetic Acid
期刊论文
结构化学, 2017, 期号: 09, 页码: 1425-1432
作者:
Zhang XS(张宪生)
;
Xin X(辛晓)
;
Liu W(刘巍)
;
Xie YF(谢亚非)
;
Liu ZY(刘长鹰)
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/12
synthesis
crystal structure
URAT1 inhibitor
lesinurad
Design, Synthesis and Biological Activity of Tetrazole-bearing Uric Acid Transporter 1 Inhibitors
期刊论文
高等学校化学研究, 2017, 卷号: 33, 期号: 1, 页码: 49-60
作者:
Cai Wenqing
;
Liu Wei
;
Xie Yafei
;
Wu Jingwei
;
Liu Yuqiang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/12
URAT1 inhibitor
Structure-activity relationship
Drug discovery
Lesinurad
Tetrazole
Bioisostere
A Systematic Review of Uric Acid Transporter 1 (URAT1) Inhibitors for the Treatment of Hyperuricemia and Gout and an Insight into the Structure-activity Relationship (SAR)
期刊论文
结构化学, 2017, 卷号: 36, 期号: 6, 页码: 897-910
作者:
Cai Wen-Qing
;
Liu Wei
;
Liu Chang-Ying
;
Wang Jian-Wu
;
Zhao Gui-Long
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/12
gout
hyperuricemia
urate-lowering therapy
uricosuric
URAT1 inhibitor
structure-activity relationship (SAR)
A Systematic Review of Uric Acid Transporter 1(URAT1) Inhibitors for the Treatment of Hyperuricemia and Gout and an Insight into the Structure-activity Relationship(SAR)
期刊论文
结构化学, 2017, 期号: 06, 页码: 897-910
作者:
Cai WQ(蔡文卿)
;
Liu W(刘巍)
;
Liu ZY(刘长鹰)
;
Wang JW(王建武)
;
Zhao GL(赵桂龙)
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/12
gout
hyperuricemia
urate-lowering therapy
uricosuric
URAT1 inhibitor
structure-activity relationship(SAR)
Discovery of a Flexible Triazolylbutanoic Acid as a Highly Potent Uric Acid Transporter 1 (URAT1) Inhibitor
期刊论文
MOLECULES, 2016, 卷号: 21, 期号: 11
作者:
Tian, He
;
Liu, Wei
;
Zhou, Zhixing
;
Shang, Qian
;
Liu, Yuqiang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
gout
hyperuricemia
URAT1 inhibitor
lesinurad
synthesis
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