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Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation
期刊论文
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:
Li, Heng
;
Zhang, Xianglei
;
Xiang, Caigui
;
Feng, Chunlan
;
Fan, Chen
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/11/04
PDE4
Arctigenin
Psoriasis
Inflammation
Transfersomes improved delivery of ascorbic palmitate into the viable epidermis for enhanced treatment of melasma
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 608, 页码: 10
作者:
Li, Junjun
;
Duan, Nianxiu
;
Song, Sha
;
Nie, Di
;
Yu, Miaorong
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/11/04
Transfersome
Drug delivery
Ascorbic palmitate
Viable epidermis
Melasma treatment
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:
Zhang, Rui
;
Li, Heng
;
Zhang, Xianglei
;
Li, Jian
;
Su, Haixia
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
PDE4 inhibitors
Tetrahydroisoquinoline
Antipsoriasis
DZ2002 alleviates psoriasis-like skin lesions via differentially regulating methylation of GATA3 and LCN2 promoters
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 91, 页码: 12
作者:
Chen, Li
;
Lin, Zemin
;
Liu, Yuting
;
Cao, Shiqi
;
Huang, Yueteng
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/05/24
DZ2002
Psoriasis
DNA methylation
Keratinocyte
Inflammatory infiltration
Facile Synthesis and Size Control of 2D Cyclodextrin-Based Metal-Organic Frameworks Nanosheet for Topical Drug Delivery
期刊论文
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, 2020, 页码: 13
作者:
Bello, Mubarak G.
;
Yang, Yingchao
;
Wang, Caifen
;
Wu, Li
;
Zhou, Panpan
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/12/24
gamma-cyclodextrin metal-organic frameworks
cubes
dexamethasone
nanosheets
ocular drug delivery
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yang, Fang-ming
;
Fan, Di
;
Yang, Xiao-qian
;
Zhu, Feng-hua
;
Shao, Mei-juan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
dry eye disease
artemisinin derivative
beta-aminoarteether maleate
inflammation
macrophages
TLR4
inflammasome
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:
Li, Heng
;
Li, Jian
;
Zhang, Xianglei
;
Feng, Chunlan
;
Fan, Chen
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/24
DC591017
PDE4
Inflammation
Macrophages
Dendritic cells
Psoriasis
DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:
Li, Heng
;
Li, Jian
;
Zhang, Xianglei
;
Feng, Chunlan
;
Fan, Chen
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/12/24
DC591017
PDE4
Inflammation
Macrophages
Dendritic cells
Psoriasis
Dual controlled release effect of montmorillonite loaded polymer nanoparticles for ophthalmic drug delivery
期刊论文
APPLIED CLAY SCIENCE, 2019, 卷号: 180, 页码: 8
作者:
Zhao, Yawen
;
Li, Juan
;
Han, Xinyue
;
Tao, Qi
;
Liu, Shuo
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/04/27
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593
作者:
Zhang, Xianglei
;
Dong, Guangyu
;
Li, Heng
;
Chen, Wuyan
;
Li, Jian
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
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