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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Low molecular weight fucoidan restores diabetic endothelial glycocalyx by targeting neuraminidase2: A new therapy target in glycocalyx shedding
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2024, 页码: 17
作者:
Li, Zhi
;
Wu, Ning
;
Wang, Jing
;
Yue, Yang
;
Geng, Lihua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/04/07
diabetic vascular complication
glycocalyx
insulin resistance
LMWF
NEU2
Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:
Hua, Chen
;
Shena, Lijuan
;
Zoua, Fengming
;
Wua, Yun
;
Wanga, Beilei
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  |  
浏览/下载:11/0
  |  
提交时间:2023/11/10
Acquired resistance mutations
CDK9 inhibitors
Transcription
Single nucleotide polymorphisms
BAY1251152
2-Methoxyestradiol loaded mesoporous polydopamine nanoprobes for hypoxia alleviation and sorafenib synergistic treatment of hepatocellular carcinoma
期刊论文
MATERIALS & DESIGN, 2023, 卷号: 232, 页码: 11
作者:
Wang, Peifeng
;
Du, Yang
;
Zhao, Xingyang
;
Hu, Yueyang
;
Zhou, Tianjun
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  |  
浏览/下载:8/0
  |  
提交时间:2023/11/17
Hepatocellular carcinoma
Mesoporous polydopamine
Photothermal therapy
Sorafenib
Hypoxia
Wnt Signaling Pathway Collapse upon beta-Catenin Destruction by a Novel Antimicrobial Peptide SKACP003: Unveiling the Molecular Mechanism and Genetic Activities Using Breast Cancer Cell Lines
期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 3, 页码: 1
作者:
Selvarathinam, Kanitha
;
Subramani, Prabhu
;
Thekkumalai, Malarvili
;
Vilwanathan, Ravikumar
;
Selvarajan, Ramganesh
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  |  
浏览/下载:16/0
  |  
提交时间:2023/04/14
antimicrobial peptides
anticancer agents
breast cancer
Wnt pathway
beta-catenin
downregulation
oncology
alternative therapy
Verteporfin reverses progestin resistance through YAP
期刊论文
CELL DEATH DISCOVERY, 2023, 卷号: 9, 期号: 1
作者:
Lina Wei
;
Xiaohong Ma
;
Yixin Hou
;
Tianyi Zhao
;
Rui Sun
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
Fucoidan, as an immunostimulator promotes M1 macrophage differentiation and enhances the chemotherapeutic sensitivity of capecitabine in colon cancer
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 222, 页码: 562-572
作者:
Deng, Zhenzhen
;
Wu, Ning
;
Suo, Qishan
;
Wang, Jing
;
Yue, Yang
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  |  
浏览/下载:25/0
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提交时间:2023/01/04
Capecitabine
Tumor microenvironment
Macrophages
TLR4
Fucoidan
The reversal of anti-HER2 resistance in advanced HER2-positive breast cancer using apatinib: two cases reports and literature review
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2022
作者:
He, Libin
;
Shen, Xiabo
;
Liu, Yiyuan
;
Gao, Lu
;
Wu, Jiayi
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
Advanced human epidermal growth factor receptor 2-positive breast cancer (advanced HER2-positive breast cancer)
apatinib
case report
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity
期刊论文
CELL DEATH & DISEASE, 2022, 卷号: 13
作者:
Wang, Ruru
;
Shang, Yajing
;
Chen, Bin
;
Xu, Feng
;
Zhang, Jie
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
Drug-resistant HER2-positive breast cancer: Molecular mechanisms and overcoming strategies
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Wu, Xiaofan
;
Yang, Hongjian
;
Yu, Xingfei
;
Qin, Jiang-Jiang
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  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
HER2
breast cancer
targeted therapy
drug resistance
overcoming strategies
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