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浏览/检索结果:
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Molecular imaging-guided extracellular vesicle-based drug delivery for precise cancer management: Current status and future perspectives
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2023, 卷号: 362, 页码: 97-120
作者:
Cheng, Zhongquan
;
Shang, Jihuan
;
Wang, Huarong
;
Yu, Leyi
;
Yuan, Zhu
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/11/16
Extracellular vesicles
Molecular imaging
Cancer
Diagnosis
Therapy
Therapeutic potential of enzymatically extracted eumelanin from squid ink in type 2 diabetes mellitus ICR mice: Multifaceted intervention against hyperglycemia, oxidative stress and depression
期刊论文
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2023, 页码: 15
作者:
Song, Wen
;
Xing, Ronge
;
Yang, Haoyue
;
Liu, Song
;
Yu, Huahua
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2023/11/30
type 2 diabetes mellitus (T2DM)
eumelanin
hypoglycemic activity
antioxidant activity
antidepressant activity
Evaluation of residual cognition in patients with disorders of consciousness based on functional near-infrared spectroscopy
期刊论文
NEUROPHOTONICS, 2023, 卷号: 10, 期号: 2, 页码: 20
作者:
Si, Juanning
;
Yang, Yi
;
Xu, Long
;
Xu, Tianshuai
;
Liu, Hao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2023/11/17
disorders of consciousness
functional near-infrared spectroscopy
residual awareness
motor imagery
hemodynamic response
Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract
期刊论文
CANCER COMMUNICATIONS, 2022
作者:
Wu, Huanwen
;
Yu, Zicheng
;
Liu, Yueping
;
Guo, Lei
;
Teng, Lianghong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/22
Neuroendocrine carcinomas
Gastrointestinal tract
Genomic characterization
Heterogeneity
Therapeutic implications
GM-Pep: A High Efficiency Strategy to De Novo Design Functional Peptide Sequences
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2022, 卷号: 62, 期号: 10, 页码: 2617-2629
作者:
Chen, Qushuo
;
Yang, Changyan
;
Xie, Yihao
;
Wang, Yuqiang
;
Li, Xiaoxu
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/06/21
BioactivityDrug interactionsLearning systemsToxicity
Auto encodersComputation methodsDe novo designFunctional peptidesHigher efficiencyMulti-classifierPeptide sequencesPeptide therapeuticsTherapeutic agentsTherapeutic peptides
A review of advances in imaging methodology in fluorescence molecular tomography
期刊论文
PHYSICS IN MEDICINE AND BIOLOGY, 2022, 卷号: 67, 期号: 10, 页码: 25
作者:
Zhang, Peng
;
Ma, Chenbin
;
Song, Fan
;
Fan, Guangda
;
Sun, Yangyang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/06/10
fluorescence tomography
forward and inverse problem
ill-posedness
reconstruction method
deep learning
Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235
作者:
Qu, Bingxue
;
Xu, Yongjin
;
Lu, Yang
;
Zhuang, Weihao
;
Jin, Xinxin
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2022/12/23
XPO1
Multiple myeloma
MM.1S
N-phenylsulfonamide
Oral administration
Efficacy and safety of radiotherapy combined with raltitrexed and irinotecan for treating unresectable recurrent colorectal cancer: a single-arm phase II trial
期刊论文
JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2022
作者:
Li, Xinghui
;
Shen, Jinwen
;
Xia, Fan
;
Zhu, Ji
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/12/23
Colorectal cancer
local recurrence
intensity-modulated radiotherapy
irinotecan
raltitrexed
Evaluation of JQ1 Combined With Docetaxel for the Treatment of Prostate Cancer Cells in 2D-and 3D-Culture Systems
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Xu, Yipeng
;
Pachnikova, Gabriela
;
Przybilla, Dorothea
;
Schafer, Reinhold
;
Cui, Yingying
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/03/28
Prostate Cancer
JQ1
Docetaxel
Combination Treatment
3D Culture Spheroid
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Li, Teng-teng
;
Peng, Cheng
;
Wang, Ji-qiu
;
Xu, Zhi-jian
;
Su, Ming-bo
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/01/18
DPP4
distal mutation
enzymatic activity
molecular dynamics simulation
structure-function mechanism
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