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CORC

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A Pathway-Specific Polygenic Risk Score Is Associated with Tau Pathology and Cognitive Decline 期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2022, 卷号: 85, 期号: 4, 页码: 1745-1754
作者:  Sun, Yuqing;  Wang, Meng;  Zhao, Yuxin;  Hu, Ke;  Liu, Yong
收藏  |  浏览/下载：23/0  |  提交时间：2022/06/06
Ameliorating Ribosylation-Induced Amyloid-beta Pathology by Berberine via Inhibiting mTOR/p70S6K Signaling 期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2021, 卷号: 79, 期号: 2, 页码: 833-844
作者:  Wang, Yang-Yang;  Yan, Qian;  Huang, Zhen-Ting;  Zou, Qian;  Li, Jing
收藏  |  浏览/下载：22/0  |  提交时间：2021/03/29
Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells 期刊论文
Frontiers in Neuroscience, 2017, 卷号: 10, 期号: 0, 页码: 598
作者:  He, Xiaping;  Li, Zhenhui;  Rizak, Joshua D.;  Wu, Shihao;  Wang, Zhengbo
收藏  |  浏览/下载：49/0  |  提交时间：2017/03/13
Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells 期刊论文
Frontiers in Neuroscience, 2017, 卷号: 10, 期号: X, 页码: e598
作者:  He XP;  Li ZH;  He RQ;  Su M;  Qin DD[*]
收藏  |  浏览/下载：38/0  |  提交时间：2017/02/20
A novel GSK-3 beta inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 6, 页码: 741-752
作者:  Pang, Tao;  Wang, Yun-jie;  Gao, Yuan-xue;  Xu, Yuan;  Li, Qiu
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08
The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect 期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 162, 页码: 179-187
作者:  Chu, Shifeng;  Liu, Shaolin;  Duan, Wenzhen;  Cheng, Yong;  Jiang, Xueying
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/27
Chirality  Clausenamide  Dementia  Long-term potentiation  Signaling pathway  Calcium  6-OHDA  6-hydroxyldopamine  ACE  acetylcholinesterase  ACh  acetylcholine  AD  Alzheimer's disease  AUC0–12 h  0–12 h area under curve  APP  amyloid precursor protein  APV  R-2-amino-5-phosphonopentanoate  AUC0−∝  whole area under curve  BBB  blood–brain barrier  BDNF  brain-derived neurotrophic factor  CaM  calmodulin  CaMKII  calmodulin kinase II  ChAT  choline acetyltransferase  CREB  cAMP responding element binding  CHM  Chinese herbal medicine  clau  clausenamide  CL  clearance  Cmax  maximum concentration  CDK-5  cyclin-dependent kinase-5  DM  diabetes mellitus  DAG  diacylglycerol  ER  endoplasmic reticulum  ERK  extracellular signal-regulated kinases  GSK-3  glycogen synthase kinase-3  IP3  inositol triphosphate  LTP  long term potentiation  MWM  Morris water maze  NGF  nerve growth factor  NMDA  N-Methyl-D-aspartate  D  nNOS  neural nitric oxide synthase  PAT  passive avoidance tasks  Pir  piracetam  PLC  phospholipase C  PP1  phosphate 1  PKC  protein kinase C  tmax  time of peak concentration  t1/2α  absorption half-life  t1/2β  elimination half-life  Tau  microtubule-associated proteins  TCM  traditional Chinese medicine  Vd  apparent volume of distribution  VDCC  voltage-dependent calcium channel  
A novel GSK-3β inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway 期刊论文
中国药理学报：英文版, 2016, 卷号: 000, 期号: 006, 页码: 741
作者:  Pang Tao;  Wang Yunjie;  Gao Yuanxue;  Xu Yuan;  Li Qiu
收藏  |  浏览/下载：14/0  |  提交时间：2020/12/24
anovelgsk3inhibitoryq138preventsneuronalinjuryinducedbyglutamateandbrainischemiathroughactivationofthenrf2signalingpathway 期刊论文
actapharmacologicasinica, 2016, 卷号: 000, 期号: 006, 页码: 741
作者:  Pang Tao;  Wang Yunjie;  Gao Yuanxue;  Xu Yuan;  Li Qiu
收藏  |  浏览/下载：3/0  |  提交时间：2020/07/01
Conditional inactivation of Akt three isoforms causes tau hyperphosphorylation in the brain 期刊论文
2015, 卷号: 10, 页码: 33
作者:  Wang, Long;  Cheng, Shanshan;  Yin, Zhenyu;  Xu, Congyu;  Lu, Shuangshuang
收藏  |  浏览/下载：4/0  |  提交时间：2020/01/13
Escitalopram Ameliorates Tau Hyperphosphorylation and Spatial Memory Deficits Induced by Protein Kinase A Activation in Sprague Dawley Rats 期刊论文
Journal of Alzheimer’s Disease, 2015, 卷号: 47, 期号: 1, 页码: 61-71
作者:  Ren QG[*];  Wang YJ;  Gong WG;  Xu L;  Zhang ZJ[*]
收藏  |  浏览/下载：19/0  |  提交时间：2015/10/12

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