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浏览/检索结果: 共8条，第1-8条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Knockdown of Hypoxia-Inducible Factor 1 alpha (HIF-1 alpha) Promotes Autophagy and Inhibits Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Ovarian Cancer Cells 期刊论文 MEDICAL SCIENCE MONITOR, 2019, 卷号: 25 作者:  Huang, Jinling;  Gao, Likun;  Li, Bingshu;  Liu, Cheng;  Hong, Shasha 收藏  |  浏览/下载：33/0  |  提交时间：2019/12/05 Autophagy  Hypoxia-Inducible Factor 1, alpha Subunit  Ovarian Neoplasms  Phosphatidylinositol 3-Kinases  Signal Transduction  TOR Serine-Threonine Kinases   Targeting mTORC1/2 Complexes Inhibit Tumorigenesis and Enhance Sensitivity to 5-Flourouracil (5-FU) in Hepatocellular Carcinoma: A Preclinical Study of mTORC1/2-Targeted Therapy in Hepatocellular Carcinoma (HCC) 期刊论文 MEDICAL SCIENCE MONITOR, 2018, 卷号: 24 作者:  Zhang, Yu;  Jia, Qing-an;  Kadel, Dhruba;  Zhang, Xiao-fei;  Zhang, Quan-bao 收藏  |  浏览/下载：9/0  |  提交时间：2019/12/05 Carcinoma, Hepatocellular  Fluorouracil  P-Glycoprotein  TOR Serine-Threonine Kinases   Collapsin Response Mediator Protein-2 Ameliorates Sevoflurane-Mediated Neurocyte Injury by Targeting PI3K-mTOR-S6K Pathway 期刊论文 MEDICAL SCIENCE MONITOR, 2018, 卷号: 24, 页码: 4982-4991 作者:  He, Jiaxuan;  Zhu, Jianfang 收藏  |  浏览/下载：5/0  |  提交时间：2019/11/19 Neurocysticercosis  Phosphatidylinositol 3-Kinases  TOR Serine-Threonine Kinases   Targeting mTORC1/2 Complexes Inhibit Tumorigenesis and Enhance Sensitivity to 5-Flourouracil (5-FU) in Hepatocellular Carcinoma: A Preclinical Study of mTORC1/2-Targeted Therapy in Hepatocellular Carcinoma (HCC) 期刊论文 MEDICAL SCIENCE MONITOR, 2018, 卷号: 24, 页码: 2735-2743 作者:  Zhang, Yu;  Jia, Qing-an;  Kadel, Dhruba;  Zhang, Xiao-fei;  Zhang, Quan-bao 收藏  |  浏览/下载：4/0  |  提交时间：2019/11/26 P-Glycoprotein  Carcinoma, Hepatocellular  TOR Serine-Threonine Kinases  Fluorouracil   mTOR modulates CD8+T cell differentiation in mice with invasive pulmonary aspergillosis 期刊论文 2018, 卷号: 13, 期号: 1, 页码: 129-136 作者:  Wang, Hao;  Xiao, Yu;  Su, Longxiang;  Cui, Na;  Liu, Dawei 收藏  |  浏览/下载：6/0  |  提交时间：2020/01/03 CD8-positive T lymphocytes  Invasive Pulmonary Aspergillosis  TOR Serine-Threonine Kinases  Immunosuppression   Hyperactivation of mTOR critically regulates abnormal osteoclastogensis in neurofibromatosis type 1. 期刊论文 J Orthop Res, 2011 - 收藏  |  浏览/下载：4/0  |  提交时间：2019/03/05 Animals  Antibiotics,  Antineoplastic/pharmacology  Bone  Marrow  Cells/cytology/physiology  Bone  Resorption/metabolism/pathology/*physiopathology  Cell  Division/physiology  Cells,  Cultured  Genotype  Male  Mice  Mice,  Mutant  Strains  Neurofibromatosis  1/metabolism/pathology/*physiopathology  Neurofibromin  1/*genetics/metabolism  Osteoclasts/pathology/*physiology  Signal  Transduction/physiology  Sirolimus/pharmacology  TOR  Serine-Threonine  Kinases/*genetics/metabolism   An investigation of reversal of imatinib resistance in the Bcr-Abl positive imatinib-resistant cell line K562r by dasatinib, nilotinib, rapamycin and bortezomib 期刊论文 FOCUS on News for You, 2010 - 收藏  |  浏览/下载：2/0  |  提交时间：2019/03/05 Antineoplastic  Agents/*pharmacology  Boronic  Acids/*pharmacology  Cell  Line,  Tumor  Cell  Proliferation/drug  effects  Drug  Resistance,  Neoplasm/*drug  effects  Fusion  Proteins,  bcr-abl/*metabolism  Humans  K562  Cells  Piperazines/*pharmacology  Pyrazines/*pharmacology  Pyrimidines/*pharmacology  Signal  Transduction/drug  effects  Sirolimus/*pharmacology  TOR  Serine-Threonine  Kinases/metabolism  Thiazoles/*pharmacology  Up-Regulation/drug  effects   Proteomic analysis revealed association of aberrant ROS signaling with suberoylanilide hydroxamic acid-induced autophagy in Jurkat T-leukemia cells 期刊论文 Medycyna Sportowa, 2010, 卷号: Vol.6 No.6, 页码: 711 - 收藏  |  浏览/下载：3/0  |  提交时间：2019/03/05 Apoptosis/drug  effects  Autophagy/*drug  effects/genetics  Gene  Expression  Regulation,  Leukemic/drug  effects  Green  Fluorescent  Proteins/metabolism  Humans  Hydroxamic  Acids/*pharmacology  Immunoblotting  Jurkat  Cells  Leukemia,  T-Cell/enzymology/genetics/*metabolism/*pathology  Microtubule-Associated  Proteins/metabolism  Models,  Biological  Neoplasm  Proteins/metabolism  Phagosomes/drug  effects/metabolism  Proteomics/*methods  Proto-Oncogene  Proteins  c-akt/antagonists  &  inhibitors/metabolism  Reactive  Oxygen  Species/*metabolism  Signal  Transduction/*drug  effects  TOR  Serine-Threonine  Kinases/antagonists  &  inhibitors  Vacuoles/drug  effects/metabolism