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Beyond the Tip of the Iceberg: Suspect Screening Reveals Point Source-Specific Patterns of Emerging and Novel Per- and Polyfluoroalkyl Substances in German and Chinese Rivers br
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, 卷号: 56, 期号: 9, 页码: 5456-5465
作者:
Joerss, Hanna
;
Menger, Frank
;
Tang, Jianhui
;
Ebinghaus, Ralf
;
Ahrens, Lutz
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/07/26
high-resolution mass spectrometry (HRMS)
quadrupole time-of-flight (QToF)
surface water
emerging contaminants
organic pollutants
PFAS
homologous series
Kendrick mass defect
Synthesis and antiviral activity of 2 '-deoxy-6 '-substituted carbocyclic nucleosides
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 12
作者:
Xue, Haitao
;
Guo, Shuang
;
Hu, Tianwen
;
Wei, Daibao
;
Xie, Yuanchao
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浏览/下载:40/0
  |  
提交时间:2022/01/18
2 '-deoxy carbocyclic nucleoside
antiviral activity
hepatitis B virus
Mitsunobu reaction
Post-Synthetic Modification Research of Salan Titanium bis-Chelates via Sonogashira Reaction
期刊论文
ACTA CHIMICA SINICA, 2021, 卷号: 79, 期号: 11, 页码: 1385-1393
作者:
Zhao, Tiankun
;
Wang, Peng
;
Ji, Mingyu
;
Li, Shanjia
;
Yang, Mingjun
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  |  
浏览/下载:24/0
  |  
提交时间:2021/12/17
Sonogashira reaction
[SalanTi((IV)) Dipic] complexes
antitumor activity
alkyne functionalization
aqueous
Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11
作者:
Li, Bo
;
Li, Heng
;
Zhu, Zhengdan
;
Xiang, Caigui
;
Xu, Zhijian
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  |  
浏览/下载:99/0
  |  
提交时间:2021/11/04
Anti-inflammatory activity
TNF alpha
ER beta
IBD Arylisoquinolones
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:
He, Qian
;
Wei, Yuanyuan
;
Liu, Xiao
;
Ye, Rongrong
;
Kong, Linghui
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  |  
浏览/下载:88/0
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提交时间:2021/11/04
The engineered biphenyl dioxygenases enhanced the metabolism of dibenzofuran
期刊论文
INTERNATIONAL BIODETERIORATION & BIODEGRADATION, 2021, 卷号: 161, 页码: 9
作者:
Wang, Yuan
;
Sun, Chengcheng
;
Min, Jun
;
Li, Bingjun
;
Li, Junde
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浏览/下载:60/0
  |  
提交时间:2021/10/20
Dibenzofuran
Burkholderia xenovorans LB400
Biphenyl dioxygenase
Enzyme engineering
Regiospecificity
Biocatalysts
Direct C4-Acetoxylation of Tryptophan and Tryptophan-Containing Peptides via Palladium(II)-Catalyzed C-H Activation
期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 12, 页码: 4699-4704
作者:
Zhang, Qiyu
;
Xie, Xiong
;
Peng, Jingjing
;
Chen, Feiyang
;
Ma, Jinyu
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  |  
浏览/下载:28/0
  |  
提交时间:2021/08/17
Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers
期刊论文
INVESTIGATIONAL NEW DRUGS, 2021, 页码: 9
作者:
Li, Meng-Zhu
;
Meng, Tao
;
Song, Shan-Shan
;
Bao, Xu-Bin
;
Ma, Lan-Ping
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/05/24
G-quadruplex stabilizer
MTR-106
BRCA-deficiency
PARP inhibitor
DNA damage
Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 31, 页码: 4
作者:
Xiang, Hao-Yue
;
Chen, Jian-Yang
;
Huan, Xia-Juan
;
Chen, Yi
;
Gao, Zhao-bing
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  |  
浏览/下载:14/0
  |  
提交时间:2021/05/24
Antiproliferative
Cancer
PARP inhibitors
Pyrrolo[12-b]pyridazine
SYNTHESIS, CHARACTERIZATION, AND DRAK2 INHIBITORY ACTIVITIES OF HYDROXYAURONEDERIVATIVESURONE DERIVATIVES
期刊论文
HETEROCYCLES, 2021, 卷号: 102, 期号: 8, 页码: 1536-1551
作者:
Zhao, MS (Zhao, Mingsheng) 1 , 2
;
Dai, CQ (Dai, Chengqiu) 3 , 4
;
Li, Y (Li, Yi) 1 , 2
;
Liu, YN (Liu, Yinan) 3
;
Li, JY (Li, Jing-Ya) 3
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浏览/下载:43/0
  |  
提交时间:2021/12/06
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