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CORC

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Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng
收藏  |  浏览/下载：19/0  |  提交时间：2022/12/23
HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers. 期刊论文
Cell chemical biology, 2019, 卷号: 26, 页码: 331-+
作者:  Mo Xiulei;  Tang Cong;  Niu Qiankun;  Ma Tingxuan;  Du Yuhong
收藏  |  浏览/下载：33/0  |  提交时间：2019/11/19
Bifunctional Chimera That Coordinately Targets Human Immunodeficiency Virus 1 Envelope gp120 and the Host-Cell CCR5 Coreceptor at the Virus-Cell Interface 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 11, 页码: 5020-5033
作者:  Rashad, Adel A.;  Song, Li-Rui;  Holmes, Andrew P.;  Acharya, Kriti;  Zhang, Shiyu
收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08
Targeting Gpr52 lowers mutant HTT levels and rescues Huntington's disease-associated phenotypes 期刊论文
BRAIN, 2018, 卷号: 141, 页码: 1782-1798
作者:  Song, Haikun;  Li, Hexuan;  Guo, Shimeng;  Pan, Yuyin;  Fu, Yuhua
收藏  |  浏览/下载：52/0  |  提交时间：2019/01/08
Structural basis of ligand binding modes at the neuropeptide Y Y-1 receptor 期刊论文
NATURE, 2018, 卷号: 556, 期号: 7702, 页码: 520-+
作者:  Yang, Zhenlin;  Han, Shuo;  Keller, Max;  Kaiser, Anette;  Bender, Brian J.
收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08
The chemical diversity and structure-based evolution of non-peptide CXCR4 antagonists with diverse therapeutic potential 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 149, 页码: 148-169
作者:  Peng, Dian;  Cao, Bin;  Zhou, Ying-Jun;  Long, Ya-Qiu
收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08
Design, synthesis and pharmacological evaluation of new acyl sulfonamides as potent and selective Bcl-2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 2, 页码: 443-454
作者:  Liu, Xiaohua;  Zhang, Yu;  Huang, Wenjing;  Tan, Wenfu;  Zhang, Ao
收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08
CMKLR1 deficiency attenuates androgen-induced lipid accumulation in mice. 期刊论文
Cellular Physiology and Biochemistry, 2018
作者:  Zhao Huashan;  Wu Linlin;  Huang Chen;  Xiang Liang;  Wang Baobei
收藏  |  浏览/下载：87/0  |  提交时间：2019/01/31
Overcoming the emerging drug resistance of smoothened: an overview of small-molecule SMO antagonists with antiresistance activity 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2018, 卷号: 10, 期号: 24, 页码: 2855-2875
作者:  Zhang, Heng;  Sun, Zhijun;  Liu, Zhaopeng;  Song, Chun
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11
A Fusion Protein of the p53 Transaction Domain and the p53-Binding Domain of the Oncoprotein MdmX as an Efficient System for High-Throughput Screening of MdmX Inhibitors 期刊论文
BIOCHEMISTRY, 2017, 卷号: 56, 期号: 25, 页码: 3273-3282
作者:  Qin, Lingyun;  Zhou, Jingjing;  Su, Zhengding;  Liu, Huili;  Huang, Yongqi
收藏  |  浏览/下载：32/0  |  提交时间：2017/12/06

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