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CORC

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Targeting KRAS mutant cancers: from druggable therapy to drug resistance 期刊论文
MOLECULAR CANCER, 2022, 卷号: 21
作者:  Zhu, Chunxiao;  Guan, Xiaoqing;  Zhang, Xinuo;  Luan, Xin;  Song, Zhengbo
收藏  |  浏览/下载：22/0  |  提交时间：2022/12/23
Silencing of the lncRNA H19 enhances sensitivity to X-ray and carbon-ions through the miR-130a-3p /WNK3 signaling axis in NSCLC cells 期刊论文
Cancer Cell International, 2021, 卷号: 21, 期号: 1, 页码: 12
作者:  Zhao,Xueshan;  Jin,Xiaodong;  Zhang,Qiuning;  Liu,Ruifeng;  Luo,Hongtao
收藏  |  浏览/下载：223/0  |  提交时间：2021/12/13
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载：28/0  |  提交时间：2021/12/16
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载：22/0  |  提交时间：2022/01/04
Synthesis and bioactivity studies of covalent inhibitors derived from (-)-Chaetominine 期刊论文
JOURNAL OF MOLECULAR STRUCTURE, 2021, 卷号: 1241, 页码: 14
作者:  Zhou, Xian;  Feng, Xuexin;  Wang, Dachi;  Chen, Deheng;  Wu, Gaoxing
收藏  |  浏览/下载：83/0  |  提交时间：2021/08/17
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng
收藏  |  浏览/下载：45/0  |  提交时间：2021/08/17
Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K-AKT-mTOR/JNK pathway 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 卷号: 53, 期号: 5, 页码: 575-583
作者:  Hu, Ke;  Li, Bo;  Ma, Ruye;  Yi, Hongfei;  Xu, Zhijian
收藏  |  浏览/下载：68/0  |  提交时间：2021/06/11
The ups, downs and new trends of IDO1 inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 12
作者:  Chen, Shulun;  Tan, Jing;  Zhang, Ao
收藏  |  浏览/下载：14/0  |  提交时间：2021/08/17
Phase III Randomized Study of Ensartinib vs Crizotinib in Anaplastic Lymphoma Kinase (ALK) POSITIVE NSCLC Patients: eXalt3 期刊论文
JOURNAL OF THORACIC ONCOLOGY, 2020, 卷号: 15
作者:  Selvaggi, G.;  Wakelee, H. A.;  Mok, T.;  Wu, Y. -L.;  Reck, M.
收藏  |  浏览/下载：28/0  |  提交时间：2020/11/30
SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:  Xia, Zong-jun;  Ji, Yin-chun;  Sun, De-qiao;  Peng, Xia;  Gao, Ying-lei
收藏  |  浏览/下载：75/0  |  提交时间：2020/12/21

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