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Design, synthesis, and biological evaluation of novel 5-Alkyl-6-Adamantylmethylpyrimidin-4(3H)-ones as HIV-1 non-nucleoside reverse-transcriptase inhibitors 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2016, 卷号: 88, 期号: 3, 页码: 380-385
作者:  Li, Wenxin;  Huang, Boshi;  Kang, Dongwei;  De Clercq, Erik;  Daelemans, Dirk
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/16
DB-02, a C-6-Cyclohexylmethyl Substituted Pyrimidinone HIV-1 Reverse Transcriptase Inhibitor with Nanomolar Activity, Displays an Improved Sensitivity against K103N or Y181C Than S-DABOs 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 11, 页码: e81489
作者:  Zhang XJ;  Lu LH;  Wang RR;  Wang YP;  Luo RH
收藏  |  浏览/下载:10/0  |  提交时间:2013/12/30
新型取代嘧啶酮类(S-DABOs)HIV-1 NNRTIs的设计、合成及活性研究 学位论文
2011
作者:  张静
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/20
Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. 期刊论文
Bioorganic and medicinal chemistry, 2011, 卷号: 19, 期号: 14, 页码: 4366-4376
作者:  Zhang J;  Zhan P;  Wu J;  Li Z;  Jiang Y
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/23
Synthesis and biological evaluation of novel dihydro-aryl/alkylsulfanyl-cyclohexylmethyl-oxopyrimidines (S-DACOs) as high active anti-HIV agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 卷号: 21, 期号: 2, 页码: 694-697
作者:  He YP[*];  Long J;  Zhang SS;  Li C;  Lai CC
收藏  |  浏览/下载:10/0  |  提交时间:2011/03/15
The anti-HIV activity of three 2-alkylsulfanyl-6-benzyl-3, 4- dihydropyrimidin-4 (3H)-one derivatives acting as non-nucleoside reverse transcriptase inhibitor in vitro 期刊论文
药学学报, 2010, 卷号: 45, 期号: 2, 页码: 228-234
作者:  Long J;  Zhang DH;  Zhang GH;  Rao ZK;  Wang YH
收藏  |  浏览/下载:15/0  |  提交时间:2010/08/19
Synthesis and in vitro anti-HIV evaluation of a new series of 6-arylmethyl-substituted S-DABOs as potential non-nucleoside HIV-1 reverse transcriptase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 卷号: 44, 期号: 3
作者:  Wang, Yue-Ping;  Chen, Fen-Er;  De Clercq, Erik;  Balzarini, Jan;  Pannecouque, Christophe
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/19
Synthesis and biological evaluation of novel 2-(substituted phenylaminocarbonylmethylthio)-6-(2,6-dichlorobenzyl)-pyrimidin-4(3H)-ones as potent HIV-1 NNRTIs. 期刊论文
Bioorganic and medicinal chemistry, 2009, 卷号: 17, 期号: 22, 页码: 7749-7754
作者:  Yu M;  Liu X;  Li
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/26
Synthesis and biological evaluation of novel 6-substituted 5-alkyl-2-(arylcarbonylmethylthio) pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 卷号: 16, 期号: 7
作者:  Wang, Yue-Ping;  Chen, Fen-Er;  De Clercq, Erik;  Balzarini, Jan;  Pannecouque, Christophe
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/19
HIV  NNRTIs  SAR  S-DABOs  
Synthesis and anti-HIV-1 activity of S-dihydro(alkyloxy)benzyloxypyrimidine derivatives 期刊论文
MONATSHEFTE FUR CHEMIE, 2008, 卷号: 139, 期号: 8, 页码: 967-974
作者:  Rao ZK;  Long J;  Zhang SS;  He M;  Ou LC
收藏  |  浏览/下载:10/0  |  提交时间:2010/08/24


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