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Paralichthys olivaceus
MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity
期刊论文
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 11
作者:
Hao, Kangwei
;
Xu, Hang
;
Jiang, Shuai
;
Sun, Li
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/04/07
Paralichthys olivaceus
necroptosis
RIPK1
RIPK3
MLKL
immune defense
NOD-like receptors in autoimmune diseases
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 15
作者:
Chen, Li
;
Cao, Shi-qi
;
Lin, Ze-min
;
He, Shi-jun
;
Zuo, Jian-ping
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
pattern recognition receptors
NOD-like receptors
autoimmune diseases
inflammasomes
inhibitors
botanicals
Complex roles of necroptosis in cancer
期刊论文
2019, 卷号: 20, 期号: 5,SI, 页码: 399-413
作者:
Zhu, Fang
;
Zhang, Wei
;
Yang, Tao
;
He, Su-dan
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
Cell death
Necroptosis
Cancer
Mixed lineage kinase domain-like protein (MLKL)
Receptor-interacting protein (RIP) kinase
RIP2 Is a Critical Regulator for NLRs Signaling and MHC Antigen Presentation but Not for MAPK and PI3K/Akt Pathways
期刊论文
FRONTIERS IN IMMUNOLOGY, 2018, 卷号: 9, 期号: 1, 页码: 18
作者:
Wu, Xiao Man
;
Chen, Wen Qin
;
Hu, Yi Wei
;
Cao, Lu
;
Nie, Pin
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2019/07/03
RIP2 deficiency
larval survival
transcriptome analysis
signaling pathways
NLRs signaling
MHC antigen presentation
在坏死中MLKL复合体的组成以及形成过程
学位论文
2017, 2015
黄德力
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2017/06/20
受体相互作用蛋白3
MLKL
细胞坏死
多聚化
RIP3
MLKL
necroptosis
oligomerization
Mixed Lineage Kinase domain Like 蛋白向细胞质膜的迁移定位导致细胞坏死
学位论文
2017, 2016
李文娟
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/06/20
Mlkl
细胞坏死
钠离子浓度上升
Rip3
向细胞质膜富集的定位转移
Mlkl
ecrosis
incresed plasmic sodium concentration
Rip3
translocation to plasma membrane
Discovery of a new class of highly potent necroptosis inhibitors targeting the mixed lineage kinase domain-like protein
期刊论文
CHEMICAL COMMUNICATIONS, 2017
Yan, Bo
;
Liu, Lei
;
Huang, Shaoqiang
;
Ren, Yan
;
Wang, Huayi
;
Yao, Zhenglin
;
Li, Lin
;
Chen, She
;
Wang, Xiaodong
;
Zhang, Zhiyuan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
CELL-DEATH
MLKL
NECROSIS
RIP3
INFLAMMATION
ACTIVATION
Mlkl and fadd are critical for suppressing progressive lymphoproliferative disease and activating the nlrp3 inflammasome
期刊论文
Cell reports, 2016, 卷号: 16, 期号: 12, 页码: 3247-3259
作者:
Zhang, Xixi
;
Fan, Cunxian
;
Zhang, Haiwei
;
Zhao, Qun
;
Liu, Yongbo
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/05/09
Natural Product Kongensin A is a Non-Canonical HSP90 Inhibitor that Blocks RIP3-dependent Necroptosis
期刊论文
Cell Chemical Biology, 2016, 卷号: 23, 期号: 2, 页码: 257-266
作者:
Wang, Lei
;
Li, Dianrong
;
Li, Chao
;
Li, Lin
;
Chen, She
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/06/20
Renoprotective approaches and strategies in acute kidney injury
期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 163, 页码: 58-73
作者:
Yang, Yuan
;
Song, Meifang
;
Liu, Yu
;
Liu, Hong
;
Sun, Lin
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/03
ACTH
Adrenocorticotropic hormone
AIF
Apoptosis inducing factor
AKI
Acute kidney injury
BMSC
Bone marrow derived stem cells
CIN
Contrast-induced nephropathy
COMP-Ang1
Cartilage oligomeric matrix protein-angiopoietin-1
CysLT1R
Cysteinyl leukotriene-1 receptor
DMARD
Disease-modifying antirheumatic drugs
eNOS
Endothelial nitric oxide synthase
eEPCs
Endothelial progenitor cells
HDAC
Histone deacetylase
HSPC
Hematopoietic stem and progenitor cells
IRI
Ischemia–reperfusion injury
ICAM-1
Intercellular adhesion molecule-1
JNK
c-Jun N-terminal kinase
KIF3B
Kinesin family member 3B
KIM-1
Kidney injury molecule 1
MAPK
Mitogen-activated protein kinase
MCP-1
Monocyte chemotactic protein-1
α-MSH
Alpha-melanocyte-stimulating hormone
MFG-E8
Milk fat globule-epidermal growth factor-factor VIII
MPT
Mitochondrial permeability transition
MSCs
Mesenchymal stem cells
NGAL
Neutrophil gelatinase-associated lipocalin
MDM2
Murine double minute-2
MMP-2
Matrix metallopeptidase 2
mTOR
Mammalian target of rapamycin
PI3K
Phosphatidylinositol-3 kinase
PACAP
Pituitary adenylate cyclase activating polypeptide
RAAS
Renin–angiotensin–aldosterone system
RANTES
Regulated upon activation normal T-cell expressed and secreted
RIP1
Receptor-interacting protein 1
TNF-α
Tumor necrosis factor-alpha
TWEAK
TNF-like weak inducer of apoptosis
VDRA
Vitamin D receptor agonist
Acute kidney injury
Kidney protection
Kidney repair
Renoprotection
Ischemia–reperfusion
Nephrotoxicity
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