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科研机构
山东大学 [2]
北京大学 [1]
上海药物研究所 [1]
中南大学 [1]
上海大学 [1]
武汉大学 [1]
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期刊论文 [7]
其他 [1]
发表日期
2019 [3]
2018 [1]
2017 [1]
2016 [2]
2014 [1]
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20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 4
作者:
Qin, Hong-You
;
Kang, Xiang-Ping
;
Hu, Hai-Yan
;
Zheng, Jing
;
Jiang, Jia-Ye
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/12/05
apoptosis
ATF4
endoplasmic reticulum stress (ER stress)
human umbilical vein endothelial cells (HUVECs)
protein kinase R-like endoplasmic reticulum kinase (PERK)
protopanaxadiol (PPD)
small interfering RNA (siRNA)
20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway
期刊论文
Journal of cellular biochemistry, 2019, 卷号: 120, 页码: 5085-5096
作者:
Wang Xue[1]
;
Xia Hua-Ying[2]
;
Qin Hong-You[3]
;
Kang Xiang-Ping[4]
;
Hu Hai-Yan[5]
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/04/22
ATF4
apoptosis
endoplasmic reticulum stress (ER stress)
human umbilical vein endothelial cells (HUVECs)
protein kinase R-like endoplasmic reticulum kinase (PERK)
protopanaxadiol (PPD)
small interfering RNA (siRNA)
Matrine improves diabetic cardiomyopathy through TGF-beta-induced protein kinase RNA-like endoplasmic reticulum kinase signaling pathway
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 8, 页码: 13573-13582
作者:
Hou, Huijuan
;
Zhang, Qianqian
;
Dong, Hongwei
;
Ge, Zhiming
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
apoptosis
diabetic cardiomyopathy (DCM)
endoplasmic reticulum (ER)
stress
matrine
protein kinase RNA-like endoplasmic reticulum kinase
expression (PERK) pathway
transforming growth factor beta (TGF-beta)
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy
期刊论文
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:
Guo, Xiaodan
;
Lv, Jianlu
;
Lu, Jian
;
Fan, Lei
;
Huang, Xi
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Ginseng
Autophagy
BACE1
ER stress
Amyloid beta
Apoptosis
APP/PS1 transgenic mice
RCN1 suppresses ER stress-induced apoptosis via calcium homeostasis and PERK-CHOP signaling
期刊论文
ONCOGENESIS, 2017
Xu, S.
;
Xu, Y.
;
Chen, L.
;
Fang, Q.
;
Song, S.
;
Chen, J.
;
Teng, J.
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2017/12/03
ENDOPLASMIC-RETICULUM STRESS
UNFOLDED PROTEIN RESPONSE
CELL LINES
TRANSMEMBRANE PROTEIN
TRANSCRIPTION FACTOR
SECRETORY PATHWAY
IP3 RECEPTOR
CA2+
RETICULOCALBIN
EXPRESSION
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells
期刊论文
Cellular Signalling, 2016, 卷号: 28, 期号: 8, 页码: 1099-1104
作者:
Wang, Jing
;
Yang, Xin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/03
4E-BP1
4E binding protein
AMPK
AMP-activated protein kinase
ATF6
activating transcription factor 6
ATP
adenosine triphosphate
DEPTOR
DEP domain containing mTOR-interacting protein
CI
complexes I
CII
complex II
CIII
complex III
CIV
complex IV
CV
complex V
eIF2α
Eukaryotic Initiation Factor 2α
ER
Endoplasmic Reticulum
ERAD
ER-associated degradation
ERO1α
ER oxidoreductase 1 α
FoxO1
Forkhead box O1
GβL
G Protein β Subunit Like Protein
GRP78
78 kDa glucose-regulated protein precursor
GSIS
glucose-stimulated insulin secretion
IRE1
Inositol-requiring enzyme 1
IRS1
Insulin receptor substrate 1
IRS2
Insulin receptor substrate 2
mLST8
mammalian lethal with sec-13 protein 8
mSin1
the mammalian stress-activated MAP kinase-interaction protein 1
mtDNA
mitochondrial deoxyribonucleic acid
mTOR
mammalian TOR
mTORC1
mTOR complex 1
mTORC2
mTOR complex 2
NADPH oxidase
Nicotinamide adenine dinucleotide phosphate-oxidase
NOS
nitric oxide synthase
O2–·
superoxide anion
H2O2
hydrogen peroxide
OH·
hydroxyl radical
3O2
triplet-state molecular oxygen
OXPHOS
oxidative phosphorylation
CAT
catalase
GPx
glutathioneperoxidase
PERK
Protein kinase R-like endoplasmic reticulum kinase
PDI
ER protein disulfide isomerases
PI3K
the phosphoinositide3-kinase
PRAS40
40-kDa proline-rich Akt substrate
PRAS40
the 40-kDa proline-rich Akt substrate
PROTOR
the protein observed with RICTOR
RAPTOR
regulatory-associated protein of mTOR
RICTOR
The rapamycin-insensitive companion of mTOR
REDD1
DNA damage response 1
RNS
reactive nitrogen species
ROS
reactive oxygen species
RNS
reactive nitrogen species
S6K
S6 kinase
SOD
superoxidedismutase
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TOR
the target of rapamycin
TSC2
Tuberous sclerosis 2
UPR
unfolded protein response
Mitochondrial oxidative stress
ER stress
mTOR
Pancreatic β cells
ERS-PERK signaling pathway-mediated Nrf2/ARE-HO-1 axis: A novel therapeutic target for attenuating myocardial ischemia and reperfusion injury
其他
2016-01-01
作者:
Wang, Jichun
;
Hu, Xiaorong
;
Jiang, Hong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
Myocardial ischemia and reperfusion injury
Endoplasmic reticulum stress (ERS)
Protein kinase-like ER kinase (PERK)
Heme oxygenase-1 (HO-1)
Nuclear factor-erythroid 2-related factor 2 (Nrf2)
Effect of siRNA PERK on Fluoride-Induced Osteoblastic Differentiation in OS732 Cells
期刊论文
BIOLOGICAL TRACE ELEMENT RESEARCH, 2014, 卷号: 159, 期号: 1-3, 页码: 434-439
作者:
Lu, Peng
;
Li, Xining
;
Ruan, Lihong
;
Xu, Hui
;
Liu, Qinyi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/17
Fluorosis
Osteoblast
Double-stranded RNA-activated protein kinase
(PKR)-like ER kinase
Osteoblastic differentiation
Small interfering
RNA
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