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20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway 期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 4
作者:  Qin, Hong-You;  Kang, Xiang-Ping;  Hu, Hai-Yan;  Zheng, Jing;  Jiang, Jia-Ye
收藏  |  浏览/下载:34/0  |  提交时间:2019/12/05
20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway 期刊论文
Journal of cellular biochemistry, 2019, 卷号: 120, 页码: 5085-5096
作者:  Wang Xue[1];  Xia Hua-Ying[2];  Qin Hong-You[3];  Kang Xiang-Ping[4];  Hu Hai-Yan[5]
收藏  |  浏览/下载:43/0  |  提交时间:2019/04/22
Matrine improves diabetic cardiomyopathy through TGF-beta-induced protein kinase RNA-like endoplasmic reticulum kinase signaling pathway 期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 8, 页码: 13573-13582
作者:  Hou, Huijuan;  Zhang, Qianqian;  Dong, Hongwei;  Ge, Zhiming
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/11
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy 期刊论文
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:  Guo, Xiaodan;  Lv, Jianlu;  Lu, Jian;  Fan, Lei;  Huang, Xi
收藏  |  浏览/下载:54/0  |  提交时间:2019/01/08
RCN1 suppresses ER stress-induced apoptosis via calcium homeostasis and PERK-CHOP signaling 期刊论文
ONCOGENESIS, 2017
Xu, S.; Xu, Y.; Chen, L.; Fang, Q.; Song, S.; Chen, J.; Teng, J.
收藏  |  浏览/下载:8/0  |  提交时间:2017/12/03
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells 期刊论文
Cellular Signalling, 2016, 卷号: 28, 期号: 8, 页码: 1099-1104
作者:  Wang, Jing;  Yang, Xin;  Zhang, Jingjing*
收藏  |  浏览/下载:28/0  |  提交时间:2019/12/03
4E-BP1  4E binding protein  AMPK  AMP-activated protein kinase  ATF6  activating transcription factor 6  ATP  adenosine triphosphate  DEPTOR  DEP domain containing mTOR-interacting protein  CI  complexes I  CII  complex II  CIII  complex III  CIV  complex IV  CV  complex V  eIF2α  Eukaryotic Initiation Factor 2α  ER  Endoplasmic Reticulum  ERAD  ER-associated degradation  ERO1α  ER oxidoreductase 1 α  FoxO1  Forkhead box O1  GβL  G Protein β Subunit Like Protein  GRP78  78 kDa glucose-regulated protein precursor  GSIS  glucose-stimulated insulin secretion  IRE1  Inositol-requiring enzyme 1  IRS1  Insulin receptor substrate 1  IRS2  Insulin receptor substrate 2  mLST8  mammalian lethal with sec-13 protein 8  mSin1  the mammalian stress-activated MAP kinase-interaction protein 1  mtDNA  mitochondrial deoxyribonucleic acid  mTOR  mammalian TOR  mTORC1  mTOR complex 1  mTORC2  mTOR complex 2  NADPH oxidase  Nicotinamide adenine dinucleotide phosphate-oxidase  NOS  nitric oxide synthase  O2–·  superoxide anion  H2O2  hydrogen peroxide  OH·  hydroxyl radical  3O2  triplet-state molecular oxygen  OXPHOS  oxidative phosphorylation  CAT  catalase  GPx  glutathioneperoxidase  PERK  Protein kinase R-like endoplasmic reticulum kinase  PDI  ER protein disulfide isomerases  PI3K  the phosphoinositide3-kinase  PRAS40  40-kDa proline-rich Akt substrate  PRAS40  the 40-kDa proline-rich Akt substrate  PROTOR  the protein observed with RICTOR  RAPTOR  regulatory-associated protein of mTOR  RICTOR  The rapamycin-insensitive companion of mTOR  REDD1  DNA damage response 1  RNS  reactive nitrogen species  ROS  reactive oxygen species  RNS  reactive nitrogen species  S6K  S6 kinase  SOD  superoxidedismutase  T1DM  Type 1 diabetes mellitus  T2DM  Type 2 diabetes mellitus  TOR  the target of rapamycin  TSC2  Tuberous sclerosis 2  UPR  unfolded protein response  Mitochondrial oxidative stress  ER stress  mTOR  Pancreatic β cells  
ERS-PERK signaling pathway-mediated Nrf2/ARE-HO-1 axis: A novel therapeutic target for attenuating myocardial ischemia and reperfusion injury 其他
2016-01-01
作者:  Wang, Jichun;  Hu, Xiaorong;  Jiang, Hong
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/05
Effect of siRNA PERK on Fluoride-Induced Osteoblastic Differentiation in OS732 Cells 期刊论文
BIOLOGICAL TRACE ELEMENT RESEARCH, 2014, 卷号: 159, 期号: 1-3, 页码: 434-439
作者:  Lu, Peng;  Li, Xining;  Ruan, Lihong;  Xu, Hui;  Liu, Qinyi
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/17


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