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Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15153-15186
作者:
Zheng, Wei
;
Wang, Zhen
;
Jiang, Xiangrui
;
Zhao, Qingjie
;
Shen, Jingshan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
Endothelial prostacyclin protects the kidney from ischemia-reperfusion injury
期刊论文
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2019, 卷号: 471, 期号: 4
作者:
Cao, Yingxue
;
Guan, Yi
;
Xu, Yun-Yu
;
Hao, Chuan-Ming
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Prostacyclin
Ischemia-reperfusion injury
IP receptor
Renal blood flow
S-Nitrosylation of Prostacyclin Synthase Instigates Nitrate Cross-Tolerance In Vivo
期刊论文
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2019, 卷号: 105, 期号: 1, 页码: 201-209
作者:
Zhou, Sheng-Nan
;
Lu, Jun-Xiu
;
Wang, Xue-Qing
;
Shan, Mei-Rong
;
Miao, Zhang
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
Chronic Methylmercury Exposure Induces Production of Prostaglandins: Evidence From A Population Study and A Rat Dosing Experiment
期刊论文
Environmental Science & Technology, 2019, 卷号: 53, 期号: 13, 页码: 7782-7791
作者:
Hang-kin Kong
;
Chun-fang Gan
;
Min Xiong
;
Kevin Wing-hin Kwok
;
Gilbert Chiu-sing Lui
;
Ping Li
;
Hing Man Chan
;
Samuel Chun-lap Lo
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/05/07
Arachidonic-acid Metabolites
Serum Metabolomics
Oxidative Stress
Maternal Plasma
Amniotic-fluid
Bile Secretion
Blood-pressure
Mercury
Prostacyclin
E-2
Cefminox, a Dual Agonist of Prostacyclin Receptor and Peroxisome Proliferator-Activated Receptor-Gamma Identified by Virtual Screening, Has Therapeutic Efficacy against Hypoxia-Induced Pulmonary Hypertension in Rats
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Xia, Jingwen
;
Yang, Li
;
Dong, Liang
;
Niu, Mengjie
;
Zhang, Shengli
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
hypoxia-induced pulmonary hypertension
prostacyclin receptor
peroxisome proliferator-activated receptor-gamma
phosphatase and tensin homolog
cyclic adenosine monophosphate
Cefminox, a Dual Agonist of Prostacyclin Receptor and Peroxisome Proliferator-Activated Receptor-Gamma Identified by Virtual Screening, Has Therapeutic Efficacy against Hypoxia-Induced Pulmonary Hypertension in Rats
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Xia, Jingwen
;
Yang, Li
;
Dong, Liang
;
Niu, Mengjie
;
Zhang, Shengli
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/11/26
prostacyclin receptor
phosphatase and tensin homolog
cyclic adenosine monophosphate
peroxisome proliferator-activated receptor-gamma
hypoxia-induced pulmonary hypertension
Formaldehyde regulates vascular tensions through nitric oxide-cGMP signaling pathway and ion channels
期刊论文
Chemosphere, 2018, 卷号: 193, 页码: 60-73
作者:
Zhang, Quanxi*
;
Tian, Peiru
;
Zhai, Miaomiao
;
Lei, Xiaodong
;
Yang, Zhenhua
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/23
Formaldehyde
Thoracic aorta ring
Vascular tension
Ion channels
Signal pathway
4-AP
4-aminopyridine
ACh
acetylcholine
l-NAME
l
NG-nitro-l-arginine methyl ester
l
ACE
angiotensin-converting enzyme
VSMCs
vascular smooth muscle cells
BKCa
big-conductance Ca2+-activated K+ channel
FA
formaldehyde
IbTx
iberiotoxin
iNOS
inducible nitric oxide synthase
KATP
ATP-sensitive K+ channel
eNOS
endothelial nitric oxide synthase
Kv
voltage-dependent K+ channel
sGC
soluble guanylate cyclase
NE
norepinephrine
nNOS
neuronal nitric oxide synthase
NS-2028
4H-8-bromo-1,2,4-oxadiazolo(3,4-d)benz(b)(1,4)oxazin-1-one
PGI2
prostacyclin
PKC
protein kinase C
cGMP
cyclic guanosine monophosphate
TEA
tetraethylammonium
Whole Genome Sequencing Identifies PTGIS as a Novel Susceptibility Gene for Idiopathic Pulmonary Arterial Hypertension
会议论文
CIRCULATION RESEARCH, 2018-12-07
作者:
Wang, Xiao-jian
;
Xu, Xi-qi
;
Sun, Kai
;
Liu, Ke-Qiang
;
Li, Su-Qi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
Pulmonary hypertension
Genetics
Prostacyclin
Whole Genome Sequencing Identifies PTGIS as a Novel Susceptibility Gene for Idiopathic Pulmonary Arterial Hypertension
期刊论文
2018, 卷号: 123, 期号: 12, 页码: E70-E70
作者:
Wang, Xiao-jian
;
Xu, Xi-qi
;
Sun, Kai
;
Liu, Ke-Qiang
;
Li, Su-Qi
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/01/03
Pulmonary hypertension
Genetics
Prostacyclin
Endothelium-independent vasorelaxant effect of 20(S)-protopanaxadiol on isolated rat thoracic aorta
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 页码: 1555-1562
作者:
Gan, Lu
;
Wang, Zhen-hua
;
Zhang, Hong
;
Zhou, Xin
;
Zhou, Hui
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2018/05/31
Ginsen
20(S)-protopanaxadiol
vasorelaxation
aortic rings
potassium channels
calcium channels
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