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上海药物研究所 [11]
山东大学 [9]
复旦大学上海医学院 [9]
南华大学 [5]
西安交通大学 [4]
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期刊论文 [42]
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Protective effects of probucol on Ox-LDL-induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells via LOX-1/ROS/MAPK signaling
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 17, 期号: 1
作者:
Zhu, Bing Bing
;
Wang, Hao
;
Chi, Yang Feng
;
Wang, Yun Man
;
Yao, Xing Mei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
epithelial-mesenchymal transition
oxidized low-density lipoprotein
probucol
lectin-like oxidized low-density lipoprotein receptor-1
mitogen-activated protein kinase pathway
Protective effects of probucol on Ox-LDL-induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells via LOX-1/ROS/MAPK signaling
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 17, 期号: 1
作者:
Zhu, Bing Bing
;
Wang, Hao
;
Chi, Yang Feng
;
Wang, Yun Man
;
Yao, Xing Mei
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
epithelial-mesenchymal transition
oxidized low-density lipoprotein
probucol
lectin-like oxidized low-density lipoprotein receptor-1
mitogen-activated protein kinase pathway
Protein markers of dysfunctional HDL in scavenger receptor class B type I deficient mice
期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2018, 卷号: 16
作者:
Cao, Jia
;
Xu, Yanyong
;
Li, Feifei
;
Shang, Liang
;
Fan, Daping
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
High density lipoprotein
Dysfunction
Protein markers
SR-BI
Probucol
Probucol improves erectile function via Activation of Nrf2 and coordinates the HO-1 / DDAH / PPAR-γ/ eNOS pathways in streptozotocin-induced diabetic rats
期刊论文
Biochemical and Biophysical Research Communications, 2018, 卷号: 507, 期号: 43469, 页码: 9-14
作者:
Hu L.-L.
;
Zhang K.-Q.
;
Tian T.
;
Zhang H.
;
Fu Q.
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/11
Diabetes mellitus
Erectile dysfunction
Nuclear factor erythroid 2–related factor 2
Probucol
Probucol protects circulating endothelial progenitor cells from ambient PM2.5 damage via inhibition of reactive oxygen species and inflammatory cytokine production in vivo
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 卷号: 16, 期号: 6, 页码: 4322-4328
作者:
Chen, Yong
;
Hu, Ke
;
Bu, Haoran
;
Si, Zhihua
;
Sun, Haihui
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
probucol
endothelial progenitor cells
PM2
5
reactive oxygen species
inflammatory cytokines
Probucol improves erectile function via Activation of Nrf2 and coordinates the HO-1 / DDAH / PPAR-gamma/ eNOS pathways in streptozotocin-induced diabetic rats
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 507, 期号: 1-4, 页码: 9-14
作者:
Hu, Liang-Liang
;
Zhang, Ke-Qin
;
Tian, Tao
;
Zhang, Hui
;
Fu, Qiang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Probucol
Nuclear factor erythroid 2-related factor 2
Erectile
dysfunction
Diabetes mellitus
Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc
期刊论文
Redox Biology, 2017, 卷号: 13, 页码: 482-497
作者:
Yang, Shikun
;
Zhao, Li
;
Han, Yachun
;
Liu, Yu
;
Chen, Chao
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/03
DN
diabetic nephropathy
ROS
reactive oxygen species
HG
high-glucose
SIRT1
sirtuin-1
Ac-H3
acetyl-histone H3
STZ
streptozotocin
AMPK
AMP-activated protein kinase
ECM
extracellular matrix
Nox2
NADPH oxidase 2
EMT
tubular epithelial-mesenchymal transition
DAPI
4′,6-diamidino-2-phenylindole 9
DHE
dihydroethidium
NDRD
non-diabetic renal disease
H&E
hematoxylin-eosin
PAS
periodic acid-Schiff
PASM
periodic acid-silver methenamine
IHC
immunohistochemistry
MDA
malondialdehyde
ChIP
chromatin immunoprecipitation
TC
total cholesterol
BUN
blood urea nitrogen
FN
fibronectin
HBA1C
glycosylated hemoglobin
Scr
serum creatinine
TG
triglyceride
Probucol
Renal injury
Diabetic nephropathy
p66Shc
Probucol Protects Endothelial Progenitor Cells Against Oxidized Low-Density Lipoprotein via Suppression of Reactive Oxygen Species Formation In Vivo
期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2016, 卷号: 39, 期号: 1, 页码: 89-101
作者:
Zhang, Qingbin
;
Chen, Liming
;
Si, Zhihua
;
Bu, Haoran
;
Narasimhulu, Chandrakala A.
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/16
Probucol
Endothelial progenitor cells
Oxidized low-density
lipoprotein
Reactive oxygen species
Probucol Improves Erectile Function by Restoring Endothelial Function and Preventing Cavernous Fibrosis in Streptozotocin-induced Diabetic Rats
期刊论文
UROLOGY, 2016, 卷号: 91, 页码: 241000000000-2.41e18
作者:
Zhang, Ke-Qin
;
Chen, Dong
;
Sun, Ding-Qi
;
Zhang, Hui
;
Li, Bo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/16
Lymphatic transport of orally administered probucol-loaded mPEG-DSPE micelles
期刊论文
DRUG DELIVERY, 2016, 卷号: 23, 期号: 6
作者:
Han, Limei
;
Yang, Qiushi
;
Shen, Teng
;
Qing, Jin
;
Wang, Jianxin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/13
Lymph duct cannulated rat model
lymphatic transport
micelles
mPEG-DSPE
probucol
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