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Structural Mechanism of Barriers to Interspecies Seeding Transmissibility of Full-Length Prion Protein Amyloid
期刊论文
CHEMBIOCHEM, 2019, 卷号: 20, 期号: 21, 页码: 2757-2766
作者:
Ma, Tao
;
Deng, Jing
;
Ma, Shaojie
;
Zhao, Weijing
;
Chang, Ziwei
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
amyloid fibrils
molecular dynamics
NMR spectroscopy
prions
seeding
species barriers
Prion dimer is heterogenous and is modulated by multiple negative and positive motifs
期刊论文
Biochemical and biophysical research communications, 2019, 卷号: 509, 期号: 2, 页码: 570-576
作者:
Gao, Zhenxing
;
Shi, Jing
;
Cai, Lili
;
Luo, Minhua
;
Wong, Boon-Seng
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  |  
浏览/下载:80/0
  |  
提交时间:2019/05/08
Prion protein
Disulfide bond
Fatal familial insomnia
Prp dimer
Prp aggregation
Prion Protein Protects Cancer Cells against Endoplasmic Reticulum Stress Induced Apoptosis
期刊论文
VIROLOGICA SINICA, 2019, 卷号: 34, 期号: 2
作者:
Gao, Zhenxing
;
Peng, Min
;
Chen, Liang
;
Yang, Xiaowen
;
Li, Huan
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  |  
浏览/下载:30/0
  |  
提交时间:2019/12/05
Endoplasmic reticulum stress
Brefeldin A (BFA)
Prion protein (PrP)
Glycosylation
Apoptosis
Prion protein is required for tumor necrosis factor (tnf)-triggered nuclear factor b (nf-b) signaling and cytokine production
期刊论文
Journal of biological chemistry, 2017, 卷号: 292, 期号: 46, 页码: 18747-18759
作者:
Wu, Gui-Ru
;
Mu, Tian-Chen
;
Gao, Zhen-Xing
;
Wang, Jun
;
Sy, Man-Sun
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/05/08
Deubiquitylation (deubiquitination)
Melanoma
Nf-b (nf-b)
Prion
Tumor necrosis factor (tnf)
Cyld
Nf-b signaling
Prp
Tnf
Prion protein is required for tumor necrosis factor (TNF)-triggered nuclear factor B (NF-B) signaling and cytokine production
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 46
作者:
Wu, Gui-Ru
;
Mu, Tian-Chen
;
Gao, Zhen-Xing
;
Wang, Jun
;
Sy, Man-Sun
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
deubiquitylation (deubiquitination)
melanoma
NF-B (NF-B)
prion
tumor necrosis factor (TNF)
CYLD
NF-B signaling
PrP
TNF
Roles of DMSO-type ruthenium complexes in disaggregation of prion neuropeptide PrP106-126
期刊论文
RSC ADVANCES, 2016
Zhu, Dengsen
;
Zhao, Cong
;
Wang, Xuesong
;
Wang, Wenji
;
Wang, Baohuai
;
Du, Weihong
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  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
ISLET AMYLOID POLYPEPTIDE
HUMAN SERUM-ALBUMIN
NAMI-A
FIBRIL FORMATION
STRUCTURAL CHARACTERISTICS
THERAPEUTIC AGENTS
PROTEIN PRP106-126
BINDING PROPERTIES
RU(III) COMPLEXES
CRYSTAL-STRUCTURE
Glycosylphos-phatidylinositol anchor modification machinery deficiency is responsible for the formation of pro-prion protein (PrP) in BxPC-3 protein and increases cancer cell motility
期刊论文
Journal of Biological Chemistry, 2016, 卷号: 291, 期号: 8
作者:
Yang, Liheng
;
Gao, Zhenxing
;
Hu, Lipeng
;
Wu, Guiru
;
Yang, Xiaowen
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Glycosylphosphatidylinositol Anchor Modification Machinery Deficiency Is Responsible for the Formation of Pro-Prion Protein (PrP) in BxPC-3 Protein and Increases Cancer Cell Motility
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 8
作者:
Yang, Liheng
;
Gao, Zhenxing
;
Hu, Lipeng
;
Wu, Guiru
;
Yang, Xiaowen
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
cell migration
cell surface
glycosylphosphatidylinositol (GPI anchor)
pancreatic cancer
prion
GPI anchor synthesis
cancer cell motility
pancreatic ductal adenocarcinoma cell
prion protein
Expression of BSE-associated proteins in the CNS and lymphoreticular tissues of cattle and buffalo
期刊论文
SCIENCE BULLETIN, 2016, 卷号: 61, 期号: 17, 页码: 1377-1383
作者:
Zhao H
;
Wang SQ
;
Qing LL
;
Liu LL
;
Zhang YP[*]
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  |  
浏览/下载:20/0
  |  
提交时间:2016/07/04
BSE
PRNP
SPRN
Cattle
Buffalo
Polo-like kinase 3 (PLK3) mediates the clearance of the accumulated PrP mutants transiently expressed in cultured cells and pathogenic PrPSc in prion infected cell line via protein interaction
期刊论文
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2015, 卷号: 62, 页码: 24-35
作者:
Wang, Hui[1]
;
Tian, Chan[2]
;
Fan, Xue-Yu[3]
;
Chen, Li-Na[4]
;
Lv, Yan[5]
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/24
Scrapie
PLK1/3
Interaction
CYTO-PrP
PG14-PrP
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