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科研机构
上海药物研究所 [6]
中南大学 [3]
湖南农业大学 [3]
福州大学 [3]
西安交通大学 [2]
复旦大学上海医学院 [2]
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期刊论文 [30]
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2021 [1]
2019 [4]
2018 [2]
2017 [4]
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2015 [2]
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Prevention of D-GalN/LPS-induced ALI by 18 beta-glycyrrhetinic acid through PXR-mediated inhibition of autophagy degradation
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 5, 页码: 13
作者:
Wu, Shouyan
;
Lu, Henglei
;
Wang, Wenjie
;
Song, Luyao
;
Liu, Meng
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
The responses of Oncorhynchus mykiss coping with BDE-47 stress via PXR-mediated detoxification and Nrf2-mediated antioxidation system
期刊论文
AQUATIC TOXICOLOGY, 2019, 卷号: 207, 页码: 63-71
作者:
Liu, Chunchen
;
Wang, Boyuan
;
Zhou, Bin
;
Jian, Xiaoyang
;
Zhang, Xinxin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/08/19
2,2 ',4,4 '-Tetrabromodiphenyl ether (BDE-47)
Antioxidation
Detoxification
Integrated biomarker response (IBR)
Oncorhynchus mykiss
Xenobiotic pregnane X receptor promotes neointimal formation in balloon-injured rat carotid arteries.
期刊论文
Journal of cellular physiology, 2019, 卷号: 234, 页码: 4342-4351
作者:
Zhang Meiqian
;
Zhang Zihui
;
Xie Xinya
;
Yao Qinyu
;
Liu Jia
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/11/19
pregnane X receptor (PXR)
neointimal formation
proliferation
migration
smooth muscle cell (SMC)
Metabolomic Approaches Reveal the Role of CAR in Energy Metabolism
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 1, 页码: 239-251
作者:
Omiecinski, Curtis J.
;
Patterson, Andrew D.
;
Smith, Philip B.
;
Tian, Yuan
;
Zhang, Limin
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  |  
浏览/下载:59/0
  |  
提交时间:2019/06/24
NR1I3
constitutive androstane receptor
metabolomics
energy metabolism
Patchouli alcohol activates PXR and suppresses the NF-κB-mediated intestinal inflammatory
期刊论文
Journal of ethnopharmacology, 2019, 卷号: 248, 页码: 112302
作者:
Zhang Guohui
;
Liu Meijing
;
Song Meng
;
Wang Jueyu
;
Cai Jiazhong
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  |  
浏览/下载:25/0
  |  
提交时间:2019/12/30
Intestinal inflammation
Nuclear factor-kappa B (NF-κB)
Patchouli alcohol (PA)
Pregnane X receptor (PXR)
Activation of PXR inhibits LPS-induced NF-kappa B activation by increasing I kappa B alpha expression in HepG2 cells
期刊论文
MOLECULAR & CELLULAR TOXICOLOGY, 2018, 卷号: 14, 页码: 93-104
作者:
Ye, Nanhui
;
Wang, Hang
;
Li, Qiaoling
;
Lin, Chaotong
;
Feng, Huahua
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/11/21
Inhibitor of kappa B alpha
Cancer prevention
Pregnane X receptor
Anti-inflammation
Regulation of pregnane-X-receptor and microRNAs on detoxification-related genes expressions in Mugilogobius abei under the exposure to diclofenac
期刊论文
ENVIRONMENTAL POLLUTION, 2018, 卷号: 233, 页码: 395-406
作者:
Ku, Peijia[1]
;
Wang, Chao[2]
;
Nie, Xiangping[3]
;
Ou, Ruikang[4]
;
Li, Kaibing[5]
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/01/02
Diclofenac
Mugilogobius abei
pxr
microRNAs
Detoxification
Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[alpha]-pyrene-induced DNA damage
期刊论文
TOXICOLOGY LETTERS, 2017, 卷号: 275
作者:
Cui, Hongmei
;
Gu, Xinsheng
;
Chen, Jingshu
;
Xie, Ying
;
Ke, Sui
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
PXR
AhR
BaP
cyp1a1
DNA damages
Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[α]-pyrene-induced DNA damage
期刊论文
Toxicology Letters, 2017, 卷号: 275, 页码: 67-76
作者:
Cui, Hongmei
;
Gu, Xinsheng
;
Chen, Jingshu
;
Xie, Ying
;
Ke, Sui
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/23
PXR
pregnane X receptor
AhR
aryl hydrocarbon receptor
DRE
dioxin response element
BaP
benzo[a]pyrene
RIF
rifampicin
H2Ax
histone 2Ax
CAR
constitutive androstane receptor
FXR
farnesoid X receptor
CYP450
cytochrome P450
EROD
7-ethoxyresorufin-O-deethylase
PAH
polycyclic aromatic hydrocarbon
ER
estrogen receptor
PXR
AhR
BaP
cyp1a1
DNA damages
Functions of pregnane X receptor in self-detoxification
期刊论文
Amino Acids, 2017, 卷号: 49, 期号: 12, 页码: 1999-2007
作者:
He, Liuqin
;
Zhou, Xihong
;
Huang, Niu
;
Li, Huan
;
Li, Tiejun
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/23
CYP450
Inflammatory response
NF-kappaB
PXR
Self-detoxification
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