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Screening of prolyl hydroxylase 2 inhibitors based on quantitative strategy of peptides
期刊论文
Journal of Chromatography A, 2022, 期号: 1679, 页码: 463411
作者:
Ying Zhang
;
Stanislas Nsanzamahoro
;
Cheng-Bo Wang
;
Wei-Feng Wang
;
Jun-Li Yang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2022/11/30
Prolyl hydroxylase 2
Traditional Chinese medicine
Hypoxia related diseases
Micellar electrokinetic chromatography
Recent Progress and Clinical Development of Inhibitors that Block MDM4/p53 Protein-Protein Interactions
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 10621-10640
作者:
Zhang, Shiyan
;
Lou, Jianfeng
;
Li, Yafang
;
Zhou, Feilong
;
Yan, Ziqin
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  |  
浏览/下载:64/0
  |  
提交时间:2021/11/04
Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 3, 页码: 397-403
作者:
Li, Chunpu
;
Hu, Sha-Sha
;
Yang, Lisheng
;
Wang, Min
;
Long, Jian-Dong
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/05/24
SIRT1
inhibitor
structure-activity relationship
interaction
deacetylase
Phage-Display Based Discovery and Characterization of Peptide Ligands against WDR5
期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 5, 页码: 12
作者:
Cao, Jiawen
;
Fan, Tiantian
;
Li, Yanlian
;
Du, Zhiyan
;
Chen, Lin
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  |  
浏览/下载:70/0
  |  
提交时间:2021/05/24
phage display
biopanning
WDR5
cocrystal structure
A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:
Wang, Zhen
;
Zhang, Hao
;
Chen, Baoen
;
Ouyang, Sisheng
;
Zheng, Tong
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  |  
浏览/下载:124/0
  |  
提交时间:2021/05/24
SPOP
Protein‐
protein interaction
Clear cell Renal Cell Carcinomas
Crystal structure
Peptide inhibitor
Chemical protein synthesis-assisted high-throughput screening strategies for D-peptides in drug discovery
期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31
作者:
Li, Ying
;
Cao, Xiuxiu
;
Tian, Changlin
;
Zheng, Ji-Shen
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  |  
浏览/下载:21/0
  |  
提交时间:2020/12/07
Chemical protein synthesis
Mirror-image proteins
Mirror-image phage display
Mirror-image one-bead one-compound (OBOC)
D-Peptide drug
A novel thrombin inhibitory peptide discovered from leech using affinity chromatography combined with ultra-high performance liquid chromatography-high resolution mass spectroscopy
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1151, 页码: 8
作者:
Huang, Qiuyang
;
Gao, Qian
;
Chai, Xiaoxin
;
Ren, Wei
;
Zhang, Guifeng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/23
Thrombin
Bioactive Compound Screening
Affinity Chromatography
Uplc-hr-ms
Leech
Thrombin Inhibitory Activity
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:
Zhang, Feng-cai
;
Sun, Zhong-ya
;
Liao, Li-ping
;
Zuo, Yu
;
Zhang, Dan
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
Isothermal kinase-triggered supramolecular assemblies as drug sensitizers
期刊论文
CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 4, 页码: 1132-1139
作者:
Liu, Dongdong
;
Miao, Zhe
;
Wu, Chengling
;
He, Fangfei
;
Ren, Peng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/03/24
discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285
作者:
Zhang Fengcai
;
Sun Zhongya
;
Liao Liping
;
Zuo Yu
;
Zhang Dan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
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