CORC

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CORC

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Pamiparib Monotherapy for Patients with Germline BRCA1/2-Mutated Ovarian Cancer Previously Treated with at Least Two Lines of Chemotherapy: A Multicenter, Open-Label, Phase II Study 期刊论文
CLINICAL CANCER RESEARCH, 2022, 卷号: 28
作者:  Wu, Xiaohua;  Zhu, Jianqing;  Wang, Jing;  Lin, Zhongqiu;  Yin, Rutie
收藏  |  浏览/下载：103/0  |  提交时间：2022/03/28
Novel poly (ADP-ribose) polymerases inhibitor DHC-1 exhibits in vitro and in vivo anticancer activity on BRCA-deficient pancreatic cancer cells 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 147, 页码: 10
作者:  Wu, Xiaochen;  Li, Qiqi;  Zhang, Fan;  Wang, Lijun;  Wang, Jun
收藏  |  浏览/下载：38/0  |  提交时间：2021/04/21
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 卷号: 11, 期号: 4, 页码: 1632-1645
作者:  Wang, Lei;  Zhu, Xi;  Li, Lili;  Li, Lin;  Fu, Li
收藏  |  浏览/下载：75/0  |  提交时间：2021/06/11
Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 31, 页码: 4
作者:  Xiang, Hao-Yue;  Chen, Jian-Yang;  Huan, Xia-Juan;  Chen, Yi;  Gao, Zhao-bing
收藏  |  浏览/下载：14/0  |  提交时间：2021/05/24
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:  Lai, Meng-zhen;  Song, Pei-ran;  Dou, Dou;  Diao, Yan-yan;  Tong, Lin-jiang
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/01
discoveryandbiologicalevaluationofn372methoxy44methylpiperazin1ylphenylamino4methyl2oxo2hpyrimido45d13oxazin14hylphenylacrylamideaspotentbrutonstyrosinekinaseinhibitors 期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 415
作者:  Lai Mengzhen;  Song Peiran;  Dou Dou;  Diao Yanyan;  Tong Linjiang
收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01
PI3K alpha inhibitors sensitize esophageal squamous cell carcinoma to radiation by abrogating survival signals in tumor cells and tumor microenvironment 期刊论文
CANCER LETTERS, 2019, 卷号: 459, 页码: 145-155
作者:  Shi, Jia-jie;  Xing, Hui;  Wang, Yu-xiang;  Zhang, Xi;  Zhan, Qi-min
收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01
Identification of amentoflavone as a potent highly selective PARP-1 inhibitor and its potentiation on carboplatin in human non-small cell lung cancer 期刊论文
2018, 卷号: 50, 页码: 88
作者:  Hu Xiao-Long[1];  Feng, Jia-Hao[1];  Thi-Anh Pham[1];  Ma, Hai-Yan[1];  Ma, Ming-Xi[2]
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/23
Discovery of novel quinazoline-2,4(1H,3H)-dione derivatives as potent PARP-2 selective inhibitors 期刊论文
2017, 卷号: 25, 期号: 15, 页码: 4045-4054
作者:  Zhao, Hailong;  Ji, Ming;  Cui, Guonan;  Zhou, Jie;  Lai, Fangfang
收藏  |  浏览/下载：4/0  |  提交时间：2020/01/04
Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics 期刊论文
ACTA PHARMACOLOGICA SINICA, 2010, 卷号: 31, 期号: 9, 页码: 1172-1180
作者:  He, Jin-xue;  Yang, Chun-hao;  Miao, Ze-hong
收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08

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