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Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:  Zhang, Ning;  Tian, Yu-Nan;  Zhou, Li-Na;  Li, Meng-Zhu;  Chen, Hua-Dong
收藏  |  浏览/下载:21/0  |  提交时间:2021/05/24
Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文
Cell Death & Disease, 2021, 卷号: 12, 期号: 2, 页码: 1
作者:  Ning Zhang;  Yu-Nan Tian;  Li-Na Zhou;  Meng-Zhu Li;  Hua-Dong Chen
收藏  |  浏览/下载:18/0  |  提交时间:2021/12/01
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:  Lai, Meng-zhen;  Song, Pei-ran;  Dou, Dou;  Diao, Yan-yan;  Tong, Lin-jiang
收藏  |  浏览/下载:34/0  |  提交时间:2020/07/01
Polymerase independent repression of FoxO1 transcription by sequence-specific PARP1 binding to FoxO1 promoter 期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 1, 页码: 12
作者:  Tian, Yu-Nan;  Chen, Hua-Dong;  Tian, Chang-Qing;  Wang, Ying-Qing;  Miao, Ze-Hong
收藏  |  浏览/下载:10/0  |  提交时间:2020/12/24
Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+
作者:  Chen, Hua-Dong;  Guo, Ne;  Song, Shan-Shan;  Chen, Chuan-Huizi;  Miao, Ze-Hong
收藏  |  浏览/下载:11/0  |  提交时间:2020/12/24
Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+
作者:  Chen, Hua-Dong;  Guo, Ne;  Song, Shan-Shan;  Chen, Chuan-Huizi;  Miao, Ze-Hong
收藏  |  浏览/下载:49/0  |  提交时间:2020/12/24
EGFR and c-MET Cooperate to Enhance Resistance to PARP Inhibitors in Hepatocellular Carcinoma 期刊论文
CANCER RESEARCH, 2019, 卷号: 79, 期号: 4
作者:  Du, Yi;  Dong, Qiongzhu;  Li, Hui;  Liu, Chunxiao;  Wei, Yongkun
收藏  |  浏览/下载:23/0  |  提交时间:2019/12/05
PI3K alpha inhibitors sensitize esophageal squamous cell carcinoma to radiation by abrogating survival signals in tumor cells and tumor microenvironment 期刊论文
CANCER LETTERS, 2019, 卷号: 459, 页码: 145-155
作者:  Shi, Jia-jie;  Xing, Hui;  Wang, Yu-xiang;  Zhang, Xi;  Zhan, Qi-min
收藏  |  浏览/下载:16/0  |  提交时间:2020/07/01
Acquired resistance of phosphatase and tensin homolog-deficient cells to poly(ADP-ribose) polymerase inhibitor and Ara-C mediated by 53BP1 loss and SAMHD1 overexpression 期刊论文
CANCER SCIENCE, 2018, 卷号: 109, 期号: 3, 页码: 821-831
作者:  Wang, Yu-Ting;  Yuan, Bo;  Chen, Hua-Dong;  Xu, Lin;  Tian, Yu-Nan
收藏  |  浏览/下载:43/0  |  提交时间:2019/01/08
Combining 53BP1 with BRCA1 as a biomarker to predict the sensitivity of poly(ADP-ribose) polymerase (PARP) inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1038-1047
作者:  Yang, Zhong-min;  Liao, Xue-mei;  Chen, Yi;  Shen, Yan-yan;  Yang, Xin-ying
收藏  |  浏览/下载:25/0  |  提交时间:2019/01/08


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