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Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun
收藏  |  浏览/下载:30/0  |  提交时间:2021/12/01
Targeting MDMX for Cancer Therapy: Rationale, Strategies, and Challenges 期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:  Yu, De-Hua;  Xu, Zhi-Yuan;  Mo, Shaowei;  Yuan, Li;  Cheng, Xiang-Dong
收藏  |  浏览/下载:19/0  |  提交时间:2020/10/26
Xanthohumol, a Prenylated Flavonoid from Hops, Induces Caspase-Dependent Degradation of Oncoprotein BCR-ABL in K562 Cells 期刊论文
ANTIOXIDANTS, 2019, 卷号: 8, 期号: 9
作者:  Lu, Xuxiu;  Geng, Jiajia;  Zhang, Jinman;  Miao, Jinlai;  Liu, Ming
收藏  |  浏览/下载:30/0  |  提交时间:2019/10/29
Xanthohumol, a Prenylated Flavonoid from Hops, Induces Caspase-Dependent Degradation of Oncoprotein BCR-ABL in K562 Cells 期刊论文
ANTIOXIDANTS, 2019, 卷号: 8, 期号: 9
作者:  Lu, Xuxiu;  Geng, Jiajia;  Zhang, Jinman;  Miao, Jinlai;  Liu, Ming
收藏  |  浏览/下载:27/0  |  提交时间:2019/10/29
Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 5, 页码: 997-1007
作者:  Trevarton, Alexander J.;  Zhou, Yan;  Yang, Dehua;  Rewcastle, Gordon W.;  Flanagan, Jack U.
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/01
Recombinant Butelase-Mediated Cyclization of the p53-Binding Domain of the Oncoprotein MdmX-Stabilized Protein Conformation as a Promising Model for Structural Investigation 期刊论文
BIOCHEMISTRY, 2019, 卷号: 58, 期号: 27, 页码: 3005-3015
作者:  Pi, Ni;  Gao, Meng;  Cheng, Xiyao;  Liu, Huili;  Kuang, Zhengkun
收藏  |  浏览/下载:71/0  |  提交时间:2019/10/14
Single Amino Acid Variant Discovery in Small Numbers of Cells 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 1, 页码: 417-425
作者:  Tan, Zhijing;  Yi, Xinpei;  Carruthers, Nicholas J.;  Stemmer, Paul M.;  Lubman, David M.
收藏  |  浏览/下载:39/0  |  提交时间:2019/03/05
Adenovirus oncoprotein E4orf6 triggers Cullin5 neddylation to activate the CLR5 E3 ligase for p53 degradation 期刊论文
Biochemical and Biophysical Research Communications, 2019, 卷号: Vol.516 No.4, 页码: 1242-1247
作者:  Guo H.;  Shen S.;  Li Y.;  Bi R.;  Zhang N.
收藏  |  浏览/下载:0/0  |  提交时间:2019/11/21
Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression. 期刊论文
Molecular cancer, 2019, 卷号: Vol.18 No.1
作者:  Chen Yunzhao;  Wang Dandan;  Peng Hao;  Chen Xi;  Han Xueping
收藏  |  浏览/下载:32/0  |  提交时间:2019/12/13
HERC4 exerts an anti-tumor role through destabilizing the oncoprotein Smo 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 513, 期号: 4, 页码: 1013-1018
作者:  Sun, Xiaohan;  Sun, Bing;  Cui, Meng;  Zhou, Zizhang
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/11
HERC4  Smo  NSCLC  Hh  


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