×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [7]
中国医学科学院 北京... [7]
中国科学院大学 [1]
武汉大学 [1]
复旦大学上海医学院 [1]
湖南中医药大学 [1]
更多...
内容类型
期刊论文 [17]
会议论文 [2]
发表日期
2022 [1]
2020 [1]
2019 [5]
2018 [3]
2017 [1]
2016 [2]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共19条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Jiang-yan
;
Qi, Shuang
;
Wu, Hong
;
Wang, Ao-li
;
Liu, Qing-wang
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2022/03/28
HER2
breast cancers
gastric cancers
irreversible inhibitor
drug resistance
Characterization of covalent binding of tyrosine kinase inhibitors to plasma proteins
期刊论文
DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 35, 期号: 5, 页码: 456-465
作者:
Liu, Xiaoyun
;
Feng, Dan
;
Zheng, Mingyue
;
Cui, Yongmei
;
Zhong, Dafang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/12/21
Covalent tyrosine kinase inhibitors
Covalent binding
Human serum albumin
Molecular docking
Quantitative calculations
Linear modeling
Species difference
Design, synthesis and biological study of potent and covalent HER-2 tyrosine kinase inhibitors with low cytotoxicity in vitro
期刊论文
CHEMICAL PAPERS, 2019, 卷号: 73, 期号: 6, 页码: 1333-1345
作者:
Jin, Shuyu
;
Sun, Xiuyun
;
Liu, Dan
;
Xie, Hua
;
Rao, Yu
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
HER-2 inhibitors
4-Anilino-3-cyanoquinoline
Covalent
Anticancer activity
The impact of neratinib with or without anti-diarrheal prophylaxis on health-related quality of life in HER2+early-stage breast cancer: Analyses from the ExteNET and CONTROL trials
会议论文
作者:
Delaloge, S.
;
Hurvitz, S.
;
Chan, N.
;
Bose, R.
;
Jankowitz, R. C.
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/05
Risk of gastrointestinal events during neratinib therapy in patients with cancer: a systematic review and meta-analysis of clinical trials
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2019, 卷号: 12, 期号: 4
作者:
Chen, Peng
;
Chen, Fuchao
;
Zhou, Benhong
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Neratinib
cancer
gastrointestinal events
risk
meta-analysis
Neratinib-based therapy in patients with metastatic HER2-positive breast cancer from Asia
期刊论文
2019
作者:
Xu Binghe
;
Kim Sung-Bae
;
Inoue Kenichi
;
Lee JuRueyJiuan
;
Zhang Bo
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Asia
HER2
efficacy
metastatic breast cancer
neratinib
pooled analysis
safety
tyrosine kinase inhibitor
Neratinib after trastuzumab-based adjuvant therapy in patients from Asia with early stage HER2-positive breast cancer
期刊论文
2019, 卷号: 15, 期号: 21, 页码: 2489-2501
作者:
Iwata Hiroji
;
Masuda Norikazu
;
Kim Sung-Bae
;
Inoue Kenichi
;
Rai Yoshiaki
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
Asia
HER2
early stage breast cancer
efficacy
extended adjuvant therapy
neratinib
safety
tyrosine kinase inhibitor
Efficacy, safety and tolerability of neratinib-based therapy in patients from Asia with metastatic HER2+breast cancer and other solid tumors: A pooled analysis of 6 clinical trials
会议论文
CANCER RESEARCH, 2018-02-01
作者:
Xu, Binghe
;
Kim, Sung-Bae
;
Inoue, Kenichi
;
Shen, Zhen-Zhou
;
Lee, Ju RueyJiuan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/01/03
Efficacy, safety and tolerability of neratinib-based therapy in patients from Asia with metastatic HER2+breast cancer and other solid tumors: A pooled analysis of 6 clinical trials
期刊论文
2018, 卷号: 78, 期号: 4
作者:
Xu, Binghe
;
Kim, Sung-Bae
;
Inoue, Kenichi
;
Shen, Zhen-Zhou
;
Lee, Ju RueyJiuan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Metabolic profiles of neratinib in rat by using ultra-high-performance liquid chromatography coupled with diode array detector and Q-Exactive Orbitrap tandem mass spectrometry
期刊论文
Biomedical Chromatography, 2018, 卷号: 32, 期号: 9, 页码: e4272
作者:
Liu, Wen*
;
Li, Sha
;
Wu, Yangke
;
Yan, Xiao
;
Zhu, Y. -M.
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
neratinib
metabolic pathway
metabolite identification
rat
©版权所有 ©2017 CSpace - Powered by
CSpace