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Revisiting the mechanism of enfuvirtide and designing an analog with improved fusion inhibitory activity by targeting triple sites in gp41 期刊论文
AIDS, 2019, 卷号: 33, 期号: 10
作者:  Xu, Wei;  Pu, Jing;  Su, Shan;  Hua, Chen;  Su, Xiaojie
收藏  |  浏览/下载:19/0  |  提交时间:2019/12/05
Small-molecule HIV-1 entry inhibitors targeting gp120 and gp41: a patent review (2010-2015) 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2017, 卷号: 27, 期号: 6
作者:  Li, Wen;  Lu, Lu;  Li, Weihua;  Jiang, Shibo
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/05
Site-specific Isopeptide Bridge Tethering of Chimeric gp41 N-terminal Heptad Repeat Helical Trimers for the Treatment of HIV-1 Infection 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:  Wang, Chao;  Li, Xue;  Yu, Fei;  Lu, Lu;  Jiang, Xifeng
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05
An effective strategy for recapitulating N-terminal heptad repeat trimers in enveloped virus surface glycoproteins for therapeutic applications 期刊论文
CHEMICAL SCIENCE, 2016, 卷号: 7, 期号: 3
作者:  Lai, Wenqing;  Wang, Chao;  Yu, Fei;  Lu, Lu;  Wang, Qian
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/05
A novel bispecific peptide HIV-1 fusion inhibitor targeting the N-terminal heptad repeat and fusion peptide domains in gp41 期刊论文
AMINO ACIDS, 2016, 卷号: 48, 期号: 12
作者:  Jiang, Xifeng;  Jia, Qiyan;  Lu, Lu;  Yu, Fei;  Zheng, Jishen
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/13
Peptide fusion inhibitors targeting the HIV-1 gp41: a patent review (2009-2014) 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2015, 卷号: 25, 期号: 2
作者:  Zhang, Dongmei;  Li, Wen;  Jiang, Shibo
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/19
Hydrophobic mutations in buried polar residues enhance HIV-1 gp41 N-terminal heptad repeat-C-terminal heptad repeat interactions and C-peptides' anti-HIV activity 期刊论文
AIDS, 2014, 卷号: 28, 期号: 9
作者:  Zheng, Baohua;  Wang, Kun;  Lu, Lu;  Yu, Fei;  Cheng, Maosheng
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/19
Covalent fusion inhibitors targeting HIV-1 gp41 deep pocket 期刊论文
氨基酸, 2013
Bai, Yu; Xue, Huifang; Wang, Kun; Cai, Lifeng; Qiu, Jiayin; Bi, Shuangyu; Lai, Luhua; Cheng, Maosheng; Liu, Shuwen; Liu, Keliang
收藏  |  浏览/下载:3/0  |  提交时间:2015/11/12
Mutations of Gln64 in the HIV-1 gp41 N-Terminal Heptad Repeat Render Viruses Resistant to Peptide HIV Fusion Inhibitors Targeting the gp41 Pocket 期刊论文
JOURNAL OF VIROLOGY, 2012, 卷号: 86, 期号: 1, 页码: 589-593
Yu, Xiaowen; Lu, Lu; Cai, Lifeng; Tong, Pei; Tan, Suiyi; Zou, Peng; Meng, Fanxia; Chen, Yinghua; Jiang, Shibo
收藏  |  浏览/下载:25/0  |  提交时间:2013/12/24
The Conserved Residue Arg46 in the N-Terminal Heptad Repeat Domain of HIV-1 gp41 Is Critical for Viral Fusion and Entry 期刊论文
PLOS ONE, 2012, 卷号: 7, 期号: 9
作者:  Wang, Xiaoyi;  Xiong, Weiliang;  Ma, Xiaochu;  Wei, Meili;  Chen, Yanxia
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/19


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