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上海药物研究所 [3]
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南华大学 [1]
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期刊论文 [8]
学位论文 [1]
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2020 [3]
2019 [2]
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2013 [2]
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生物资源::功能基因... [1]
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Characterization and directed evolution of propionyl-CoA carboxylase and its application in succinate biosynthetic pathway with two CO2 fixation reactions
期刊论文
METABOLIC ENGINEERING, 2020, 卷号: 62, 页码: 42-50
作者:
Liu, Xiutao
;
Feng, Xinjun
;
Ding, Yamei
;
Gao, Wenjie
;
Xian, Mo
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2021/04/12
Propionyl-CoA carboxylase
Carboxyl transferase
Directed evolution
Succinate biosynthesis
CO2 fixation
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:
Zhang, Feng-cai
;
Sun, Zhong-ya
;
Liao, Li-ping
;
Zuo, Yu
;
Zhang, Dan
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  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285
作者:
Zhang Fengcai
;
Sun Zhongya
;
Liao Liping
;
Zuo Yu
;
Zhang Dan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:
Wang, Jing-Nan
;
Che, Yun
;
Yuan, Zu-Yang
;
Lu, Zhi-Liang
;
Li, Yuan
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  |  
浏览/下载:75/0
  |  
提交时间:2019/03/18
Acetyl-macrocalin B
Reactive oxygen species
p38 MAPK
Chk1/Chk2
Esophageal squamous cell carcinoma
Association between NAT2 polymorphisms and acute leukemia risk A meta-analysis
期刊论文
MEDICINE, 2019, 卷号: 98, 期号: 12
作者:
Zhu, Xiaoxiao
;
Liu, Yanbing
;
Chen, Guangwu
;
Guo, Qiang
;
Zhang, Zhen
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  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
acute leukemia risk
meta-analysis
N-acetyl-transferase 2
polymorphism
Unusual acylation of chloramphenicol in Lysobacter enzymogenes , a biocontrol agent with intrinsic resistance to multiple antibiotics
期刊论文
BMC BIOTECHNOLOGY, 2017, 卷号: 17, 页码: 59-67
作者:
Wei Zhang
;
Justin Huffman
;
Shengying Li
;
Yuemao Shen
;
Liangcheng Du
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2018/01/05
Catalytic Mechanism of Histone Acetyltransferase p300: From the Proton Transfer to Acetylation Reaction
期刊论文
JOURNAL OF PHYSICAL CHEMISTRY B, 2014, 卷号: 118, 期号: 8, 页码: 2009-2019
作者:
Zhang, Xinlei
;
Ouyang, Sisheng
;
Kong, Xiangqian
;
Liang, Zhongjie
;
Lu, Junyan
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  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
以微拟球藻为模式的微藻产油功能基因组学研究
学位论文
博士, 北京: 中国科学院研究生院, 2013
作者:
李敬
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  |  
浏览/下载:250/0
  |  
提交时间:2013/07/13
生物燃料
微拟球藻
功能基因组学
脂组
基因组
转录组
模式体系
Molecular mechanisms for the anti-cancer effects of diallyl disulfide
期刊论文
Food and Chemical Toxicology, 2013, 卷号: 57, 页码: 362-370
作者:
Yi, Lan
;
Su, Qi*
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/27
OSCs
organosulfur compounds
DAS
diallyl sulfide
DADS
diallyl disulfide
DATS
diallyl trisulfide
MNU
testosterone- and N-methyl-N-nitrosourea
NDEA
N-nitrosodiethylamine
MPN
methyl-n-pentylnitrosamine
TPA
12-O-tetradecanoylphorbol-13-acetate
ODC
ornithine decarboxylase
QR
quinone reductase
GT
glutathione transferase
GSH
glutathione
rGSTA5
glutathione S-transferase A5
rAFAR1
aflatoxin B1 aldehyde reductase 1
AOM
azoxymethane
NDEA
nitrosodiethylamine
NAT
N-acetyltransferase
2-AAF
N-acetyl-2-aminofluorene
MAP
Mitogen-activated protein
Rac2
Ras-related C3 botulinum toxin substrate 2
NAC
N-acetyl cysteine
PARP
poly(adenosine diphosphate-ribose) polymerase
NF-κB
nuclear factor-kappa B
ER
endoplasmic reticulum
CTX
cyclophosphamide
HDAC
Histone deacetylase
MMPs
matrix metalloproteinases
(TNF)α
tumor necrosis factor
MIF
migration inhibitory factor
SSH
suppressive subtractive hybridization
Diallyl disulfide
Cell cycle
Apoptosis
Differentiation
Angiogenesis
Invasion
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