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The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein-Protein Interaction 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2020, 卷号: 27, 期号: 33, 页码: 5530-5542
作者:  Ye, Xiaoqing;  Chen, Gang;  Jin, Jia;  Zhang, Binzhong;  Wang, Yinda
收藏  |  浏览/下载:14/0  |  提交时间:2020/12/24
The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 4, 页码: 638-645
作者:  Ye, Xiaoqing;  Zhang, Rukang;  Lian, Fulin;  Zhang, Weiyao;  Lu, Wenchao
收藏  |  浏览/下载:3/0  |  提交时间:2020/07/01
Transcriptional activation of ANO1 promotes gastric cancer progression 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 512, 期号: 1
作者:  Zeng, Xiaoqing;  Pan, Duyi;  Wu, Hao;  Chen, Hao;  Yuan, Wei
收藏  |  浏览/下载:24/0  |  提交时间:2019/12/05
组蛋白甲基化酶MLL1在小鼠围着床期子宫内膜的表达 期刊论文
Medical Journal of Wuhan University, 2019, 期号: 03
作者:  黄蕾;  瞿鑫兰;  熊峣;  文雪;  张元珍
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/05
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors 期刊论文
CELL, 2018, 卷号: 175, 期号: 1, 页码: 186-+
作者:  Huang, Xun;  Yan, Juan;  Zhang, Min;  Wang, Yafang;  Chen, Yi
收藏  |  浏览/下载:77/0  |  提交时间:2019/01/08
The long noncoding RNA GAS8-AS1 suppresses hepatocarcinogenesis by epigenetically activating the tumor suppressor GAS8 期刊论文
The Journal of biological chemistry, 2018, 卷号: 293, 期号: 44, 页码: 17154-17165
作者:  Pan W.;  Zhang N.;  Liu W.;  Liu J.;  Zhou L.
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/11
The long noncoding RNA GAS8-AS1 suppresses hepatocarcinogenesis by epigenetically activating the tumor suppressor GAS8 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 44, 页码: 17154-17165
作者:  Pan, Wenting;  Zhang, Nasha;  Liu, Wenjuan;  Liu, Jibing;  Zhou, Liqing
收藏  |  浏览/下载:17/0  |  提交时间:2019/12/11
Piribedil disrupts the MLL1-WDR5 interaction and sensitizes MLL-rearranged acute myeloid leukemia (AML) to doxorubicin-induced apoptosis 期刊论文
CANCER LETTERS, 2018, 卷号: 431, 页码: 150-160
作者:  Zhang, Xiong;  Zheng, Xingling;  Yang, Hong;  Yan, Juan;  Fu, Xuhong
收藏  |  浏览/下载:37/0  |  提交时间:2019/01/08
MLL1介导的H3K4甲基化修饰在双酚A影响胚胎着床中的机制研究 科研项目
2017
作者:  张元珍
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/05
Design and synthesis of benzylpiperidine inhibitors targeting the menin-mll1 interface 期刊论文
Bioorganic & medicinal chemistry letters, 2016, 卷号: 26, 期号: 18, 页码: 4472-4476
作者:  Ren, Jing;  Xu, Wei;  Tang, Le;  Su, Minbo;  Chen, Danqi
收藏  |  浏览/下载:31/0  |  提交时间:2019/05/09


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