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中国医学科学院 北京... [4]
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期刊论文 [13]
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UPLC-Q/TOF-MS-Based Serum Metabolomics Reveals Hypoglycemic Effects of Rehmannia glutinosa, Coptis chinensis and Their Combination on High-Fat-Diet-Induced Diabetes in KK-Ay Mice
期刊论文
2018, 卷号: 19, 期号: 12
作者:
Qin, Zhenxian
;
Wang, Wei
;
Liao, Dengqun
;
Wu, Xiaoying
;
Li, Xian'en
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
Rehmannia glutinosa
Coptis chinensis
hypoglycemic effect
high-fat diet
diabetes
metabolomics
UPLC-Q
TOF-MS
Changes in Synaptic Plasticity and Glutamate Receptors in Type 2 Diabetic KK-Ay Mice
期刊论文
2017, 卷号: 57, 期号: 4, 页码: 1207-1220
作者:
Yin, Huajing
;
Wang, Weiping
;
Yu, Wenwen
;
Li, Jiang
;
Feng, Nan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/04
AMPA receptor
diabetic encephalopathy
KK-Ay mice
long-term potentiation
NMDA receptor
type 2 diabetes mellitus
Hypoglycemic Activity and the Potential Mechanism of the Flavonoid Rich Extract from Sophora tonkinensis Gagnep. in KK-Ay Mice
期刊论文
FRONTIERS IN PHARMACOLOGY, 2016, 卷号: 7
作者:
Huang, Mi
;
Deng, Shihao
;
Han, Qianqian
;
Zhao, Ping
;
Zhou, Qi
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
hypoglycemic agents
Sophora tonkinensis Gagnep.
KK-Ay mice
GLUT4
p-AMPK
Antidiabetic effects of flavonoids from Sophora flavescens EtOAc extract in type 2 diabetic KK-ay mice
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2015, 卷号: 171, 页码: 161-170
作者:
Yang, Xinzhou
;
Yang, Jing
;
Xu, Chan
;
Huang, Mi
;
Zhou, Qi
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Antidiabetic
Sophora flavescens
KKAy mice
GLUT4
AMPK
Off-line HPLC-NMR
High Insulin Levels in KK-Ay Diabetic Mice Cause Increased Cortical Bone Mass and Impaired Trabecular Micro-Structure
期刊论文
2015, 卷号: 16, 期号: 4, 页码: 8213-8226
作者:
Fu, Cen
;
Zhang, Xiaolin
;
Ye, Fei
;
Yang, Jianhong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/13
T2DM
KK-Ay mice
insulin
BMD
bone structure
osteoblast
osteoclast
THE EFFECTS OF CHINESE HERBAL SHENQI DECOCTION ON INSULIN RESISTANCE AND FATTY LIVER IN GENETICALLY DIABETIC KK-AY MICE
期刊论文
2014, 卷号: 106, 页码: S162-S162
作者:
Cho, Y. -M.[1]
;
Xie, C. -G.[1,2]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/16
Liraglutide ameliorates glycometabolism and insulin resistance through the upregulation of GLUT4 in diabetic KKAy mice
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2013, 卷号: 32, 期号: [db:dc_citation_issue], 页码: 892-900
作者:
Chen, Li-Na
;
Lyu, Juan
;
Yang, Xue-Fei
;
Ji, Wen-Jun
;
Yuan, Bing-Xiang
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/10
glycometabolism
glucose transporter 4
KK/Upj-Ay/J mice
liraglutide
insulin resistance
DYNAMIC METABOLIC PROFILING OF URINE FROM TYPE 2 DIABETIC KK-AY MICE TREATED WITH REPAGLINIDE BY GC-MS
期刊论文
2012, 卷号: 45, 期号: 13, 页码: 1862-1874
作者:
Yi, Haiyang
;
Yi, Lunzhao
;
He, Ruihua
;
Lv, Qin
;
Ren, Xiufen
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/13
KK-A(y) mice
Metabolomics
Principal component analysis (pca)
Repaglinide
Type 2 diabetes mellitus
Quantitative proteomic analysis of s-nitrosated proteins in diabetic mouse liver with icat switch method
期刊论文
Protein & cell, 2010, 卷号: 1, 期号: 7, 页码: 675-687
作者:
Zhang, Xu
;
Huang, Bo
;
Zhou, Xixi
;
Chen, Chang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/05/10
Icat switch
Mass spectrometry
Quantitative
S-nitrosation
Type 2 diabetes
Effects of Panax notoginseng saponins on anti-hyperglycemic, anti-obese and prevention from kidney pathological changes in KK-Ay mice
期刊论文
Journal Of Chinese Medicinal Materials, 2009, 卷号: Vol.32 No.10, 页码: 1571
-
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/03/05
Animals
Anti-Obesity
Agents/pharmacology
Blood
Glucose/drug
effects
Body
Weight/drug
effects
Diabetes
Mellitus,
Type
2/blood/*drug
therapy/metabolism
Diabetic
Nephropathies/*prevention
&
control
Dose-Response
Relationship,
Drug
Glucose
Tolerance
Test
Hypoglycemic
Agents/*pharmacology
Insulin/diagnostic
use/metabolism
Insulin
Resistance
Lipids/blood
Male
Mice
Mice,
Inbred
C57BL
Obesity/prevention
&
control
Panax/*chemistry
Plant
Roots/chemistry
Random
Allocation
Saponins/chemistry/*pharmacology
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