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An enhanced strategy integrating offline two-dimensional separation with data independent acquisition mode and deconvolution: Characterization of metabolites of Uncaria rhynchophylla in rat plasma as a case
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 8
作者:
Li, Haojv
;
Wei, Wenlong
;
Li, Zhenwei
;
Wang, Mengyuan
;
Wei, Xuemei
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/11/04
Off-line 2D separation system
Metabolites characterization in vivo
Data independent acquisition
Multi-dimensional deconvolution
Uncaria rhynchophylla
Systematic comparison of metabolic differences of Uncaria rhynchophylla in rat, mouse, dog, pig, monkey and human liver microsomes
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 页码: 7
作者:
Li, Hao-Jv
;
Wei, Wen-Long
;
Li, Zhen-Wei
;
Yao, Chang-Liang
;
Wang, Meng-Yuan
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2020/12/24
Uncaria rhynchophylla
Indole alkaloids
Mass defect filter
Time-staggered targeted ion lists
Metabolite identification
Liver microsomes
Isorhynchophylline enhances Nrf2 and inhibits MAPK pathway in cardiac hypertrophy
期刊论文
Naunyn-Schmiedeberg's Archives of Pharmacology, 2019
作者:
Zhang Y.
;
Cui Y.
;
Dai S.
;
Deng W.
;
Wang H.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
Cardiac hypertrophy
Fibrosis
Isorhynchophylline
Oxidative stress
Remodeling
Simultaneous determination of eight bioactive compounds by LC-MS/MS and its application to the pharmacokinetics, liver first-pass effect, liver and brain distribution of orally administrated Gouteng-Baitouweng (GB) in rats
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2018, 卷号: 1084, 页码: 122-131
作者:
Tian, Xiaoting
;
Xu, Zhou
;
Chen, Mingcang
;
Hu, Pei
;
Liu, Fang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Gouteng-Baitouweng
LC-MS/MS
Pharmacokinetics
Liver
Brain
liver first-pass effect
Characteristic Chromatogram: A Method of Discriminate and Quantitative Analysis for Quality Evaluation of Uncaria Stem with Hooks
期刊论文
PLANTA MEDICA, 2018, 卷号: 84, 期号: 6-7, 页码: 449-456
作者:
Hou, Jinjun
;
Feng, Ruihong
;
Zhang, Yibei
;
Pan, Huiqin
;
Yao, Shuai
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Uncaria rhynchophylla
Rubiaceae
isorhynchophylline
European pharmacopeia
multiple botanical origins
quality control
The effects of genetic variation and environmental factors on rhynchophylline and isorhynchophylline in Uncaria macrophylla Wall. from different populations in China
期刊论文
2018, 卷号: 13, 期号: 6, 页码: e0199259
作者:
Song, Mei-Fang
;
Guan, Yan-Hong
;
Li, Hai-Tao
;
Wei, Shu-Gen
;
Zhang, Li-Xia
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Supercritical fluid chromatography for separation and preparation of tautomeric 7-epimeric spiro oxindole alkaloids from Uncaria macrophylla
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2017, 卷号: 134, 页码: 352-360
作者:
Yang, Wenzhi
;
Zhang, Yibei
;
Pan, Huiqin
;
Yao, Changliang
;
Hou, Jinjun
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Spiro oxindole alkaloid
Uncaria macrophylla
Isomerization
Ultra-performance convergence chromatography
Preparative scale supercritical fluid chromatography
Indole Alkaloids Inhibiting Neural Stem Cell from Uncaria rhynchophylla.
期刊论文
Natural products and bioprospecting, 2017, 卷号: 7, 期号: 5, 页码: 413-419
作者:
Wei, Xin
;
Jiang, Li-Ping
;
Guo, Ying
;
Khan, Afsar
;
Liu, Ya-Ping
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/03/29
Indole Alkaloids Inhibiting Neural Stem Cell from Uncaria rhynchophylla
期刊论文
Nat. Prod. Bioprospect., 2017, 卷号: **, 期号: **, 页码: published online
作者:
Wei X
;
Guo Y
;
Chen YB
;
Wang YF*
;
Luo XD*
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2017/10/12
Indole Alkaloids
Nscs Proliferation
Uncaria Rhynchophylla
New monoterpenoid oxindole alkaloid derivatives from the stems of Uncaria hirsuta Havil. and their cytotoxicity and tandem mass spectrometric fragmentation
期刊论文
FITOTERAPIA, 2017, 卷号: 116, 页码: 85-92
作者:
Pan, Hui-qin
;
Yang, Wen-zhi
;
Zhao, Dan
;
Luo, Cheng
;
Yao, Chang-liang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Uncaria hirsuta
Monoterpenoid oxindole alkaloid
MDA-MB-231
Collision-induced dissociation
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