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上海药物研究所 [27]
兰州大学 [26]
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大连化学物理研究所 [10]
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期刊论文 [144]
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浏览/检索结果:
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GM-Pep: A High Efficiency Strategy to De Novo Design Functional Peptide Sequences
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2022, 卷号: 62, 期号: 10, 页码: 2617-2629
作者:
Chen, Qushuo
;
Yang, Changyan
;
Xie, Yihao
;
Wang, Yuqiang
;
Li, Xiaoxu
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/21
BioactivityDrug interactionsLearning systemsToxicity
Auto encodersComputation methodsDe novo designFunctional peptidesHigher efficiencyMulti-classifierPeptide sequencesPeptide therapeuticsTherapeutic agentsTherapeutic peptides
Egr2 contributes to age-dependent vulnerability to sevoflurane-induced cognitive deficits in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Chen, Ye-ru
;
Zhang, Shu-xia
;
Fang, Man
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/12/23
sevoflurane
learning ability impairment
hippocampus
early growth response 2
brain-derived neurotrophic factor
dendritic spins
nuclear factors of activated T-cell
Integrated Transcriptomics and Reverse Pharmacophore Mapping-based Network Pharmacology to Explore the Mechanisms of Natural Compounds against Doxorubicin-induced Cardiotoxicity
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2022, 卷号: 25
作者:
Zhu, Junfeng
;
Yi, Xiaojiao
;
Ding, Haiying
;
Zhong, Like
;
Fang, Luo
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/12/22
Doxorubicin-induced cardiotoxicity
natural compounds
mechanism of action
gene expression profile
bioinformatics
network pharmacology
An Integrated Strategy to Identify and Quantify the Quality Markers of Xinkeshu Tablets Based on Spectrum-Effect Relationship, Network Pharmacology, Plasma Pharmacochemistry, and Pharmacodynamics of Zebrafish
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Wei, YH
;
Nie, L
;
Gao, LL
;
Zhong, L
;
Sun, ZY
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/12/02
Multivariate Statistical Analysis of Metabolites in Anisodus tanguticus (Maxim.) Pascher to Determine Geographical Origins and Network Pharmacology
期刊论文
FRONTIERS IN PLANT SCIENCE, 2022, 卷号: 13
作者:
Chen, C
;
Wang, B
;
Li, JJ
;
Xiong, F
;
Zhou, GY
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/12/02
Exploring biological basis of Syndrome differentiation in coronary heart disease patients with two distinct Syndromes by integrated multi-omics and network pharmacology strategy
期刊论文
Chinese Medicine, 2021, 卷号: 16, 期号: 1
作者:
Wu,Gaosong
;
Zhao,Jing
;
Zhao,Jing
;
Song,Nixue
;
Zheng,Ningning
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/12/01
Coronary heart disease
Syndrome differentiation
Traditional Chinese Medicine
Proteomics
Metabolomics
Network pharmacology
Insight into chemical basis of traditional Chinese medicine based on the state-of-the-art techniques of liquid chromatography-mass spectrometry
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1469-1492
作者:
Yu, Yang
;
Yao, Changliang
;
Guo, De-an
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
Liquid chromatography-mass spectrometry
Qualitative analysis
Traditional Chinese medicine
Data acquisition
Data post-processing
Comprehensive evaluation of NAODESHENG by combining UPLC quantitative fingerprint and antioxidant activity
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 193, 页码: 7
作者:
Liao, Jun-cheng
;
Wu, Yun-shan
;
Xu, Fang-fang
;
Chen, Wei-ying
;
Zheng, Zuo-liang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Determination of content
NAODESHENG
Multi-wavelength fusion fingerprint
Anti-oxidation
Traditional Chinese Medicine (TCM)
Determination of the antidiabetic chemical basis of Phellodendri Chinensis Cortex by integrating hepatic disposition in vivo and hepatic gluconeogenese inhibition in vitro
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 263, 页码: 10
作者:
Tian, Xiaoting
;
Xu, Zhou
;
Hu, Pei
;
Yu, Yanyan
;
Li, Zhixiong
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2020/12/21
Phellodendri Chinensis cortex
Hepatic disposition
Pharmacokinetics
Berberine
Metabolites
Hepatic gluconeogenesis
Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Shikonin in Colon Cancer
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11
作者:
Chen, Yang
;
Gao, Yun
;
Yi, Xiaojiao
;
Zhang, Jinghui
;
Chen, Zhongjian
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/12/28
transcriptomics
metabolomics
shikonin
colon cancer
purine metabolism
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