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Potential Chemoprevention of Paeoniflorin in Colitis-Associated Colorectal Cancer by Network Pharmacology, Molecular Docking, and In Vivo Experiment
期刊论文
CHEMISTRY & BIODIVERSITY, 2022, 卷号: 19, 期号: 8
作者:
Si, Xiao-Li
;
Wang, Yan
;
Song, Bo-Ni
;
Zhang, Yan
;
Yang, Qing-Xia
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/09/22
network pharmacology
molecular docking
paeoniflorin
colitis-associated colorectal cancer
IL-6
STAT3
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:
Gao, Dingding
;
Jin, Nan
;
Fu, Yixian
;
Zhu, Yueyue
;
Wang, Yujie
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/06/11
STAT3 signaling pathway
Benzothiazole
Rational design
Antitumor activity
Molecular docking
Quantitative Proteomics Reveals the Protective Effects of Huangqi Decoction Against Acute Cholestatic Liver Injury by Inhibiting the NF-kappa B/IL-6/STAT3 Signaling Pathway
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2020, 卷号: 19, 期号: 2, 页码: 677-687
作者:
Wu, Jia-Sheng
;
Liu, Qian
;
Fang, Shan-Hua
;
Liu, Xing
;
Zheng, Min
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
intrahepatic cholestasis
Huangqi decoction
proteomics
NF-kappa B
IL-6
STAT3
3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:
Shan, Hui
;
Yao, Sheng
;
Ye, Yang
;
Yu, Qiang
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
JAK/STAT
3-deoxy-2 beta,16-dihydroxynagilactone E
tyrosine kinase inhibitor
allosteric inhibitor
cancer
The Protective Effect of Magnesium Lithospermate B on Hepatic Ischemia/Reperfusion via Inhibiting the Jak2/Stat3 Signaling Pathway
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 13
作者:
Zhang, Ning
;
Han, Li
;
Xue, Yaru
;
Deng, Qiangqiang
;
Wu, Zhitao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
magnesium lithospermate B
hepatic ischemia/reperfusion
acute injury
anti-inflammation
Jak2/Stat3 signaling pathway
Synthetic derivatives of the natural product 13-amino 2-desoxy-4-epi-pulchellin inhibit STAT3 signaling and induce G2/M arrest and death of colon cancer cells
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 782-785
作者:
Niu, Junxing
;
Huang, Hui
;
Wang, Fei
;
Zhang, Xianjing
;
Liu, Yi
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Sesquiterpene-lactone
JAK2/STAT3
Michael addition reaction
Antitumor
Colorectal carcinoma
2-ethoxystypandrone, a novel small-molecule stat3 signaling inhibitor from polygonum cuspidatum, inhibits cell growth and induces apoptosis of hcc cells and hcc cancer stem cells
期刊论文
Bmc complementary and alternative medicine, 2019, 卷号: 19, 页码: 13
作者:
Li, Wuguo
;
Zhang, Qing
;
Chen, Kaotan
;
Sima, Zhenhua
;
Liu, Jingli
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2019/05/08
Polygonum cuspidatum
2-ethoxystypandrone
Hepatocellular carcinoma
Cancer stem cells
Stat3 signaling pathway
Cancer stemness inhibitor
2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells
期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019, 卷号: 19, 页码: 13
作者:
Li, Wuguo
;
Zhang, Qing
;
Chen, Kaotan
;
Sima, Zhenhua
;
Liu, Jingli
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
Polygonum cuspidatum
2-Ethoxystypandrone
Hepatocellular carcinoma
Cancer stem cells
STAT3 signaling pathway
Cancer stemness inhibitor
IL-6 promotes endometrial cancer cells invasion and migration through signal transducers and activators of transcription 3 signaling pathway
期刊论文
PATHOLOGY RESEARCH AND PRACTICE, 2019, 卷号: 215, 期号: 6
作者:
Che, Qi
;
Xiao, Xirong
;
Liu, Miao
;
Lu, Yongning
;
Doug, Xi
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/12/05
Endometrial carcinoma
IL-6
Stat3
Invasion
Migration
Ilamycin C induces apoptosis and inhibits migration and invasion in triple-negative breast cancer by suppressing IL-6/STAT3 pathway
期刊论文
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2019, 卷号: 12, 页码: 60
作者:
Ma, Junying
;
Xie, Qing
;
Yang, Zhijie
;
Huang, Xuanmei
;
Zhang, Zikang
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/09/09
Ilamycin C
Triple-negative breast cancer
Apoptosis
Invasion
Migration
IL-6
STAT3
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