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IL-9 and Th9 cells in health and diseases—From tolerance to immunopathology
期刊论文
Cytokine and Growth Factor Reviews, 2017, 卷号: 37, 页码: 47-55
作者:
Li, Junhui
;
Chen, Shuqiu
;
Xiao, Xiang
;
Zhao, Yong
;
Ding, Wenjun
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/03
TNFRSF
Tumor necrosis factor receptor super family
GITR
Glucocorticoid-induced tumor necrosis factor receptor
DR3
Death receptor 3
ILC2
Type II innate lymph cells
CNS
Conserved non-coding sequences
TSS
Transcription start site
TCR
T cell receptor
NICD
Notch intracellular domain
CIS
Cytokine-induced SH-2
SOCS
Suppressor of cytokine signaling
NIK
NF-Kb inducing kinase
TL1A
TNF-like ligand 1A
IBD
Inflammatory bowel diseases
MS
Multiple sclerosis
SLE
Systemic lupus erythematosus
RA
Rheumatic arthritis
EAE
Experimental autoimmune encephalomyelitis
MOG
Myelin oligodendrocyte glycoprotein
IRF4
IFN-regulation factor 4
mAb
Monoclonal antibody
Th9
Transcription mechanism
Immunity and immunopathology
Therapeutic purposes
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
Calmodulin kinase II inhibitor regulates calcium homeostasis changes caused by acute beta-adrenergic receptor agonist stimulation in mouse ventricular myocytes
期刊论文
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2016, 卷号: 52, 期号: 2
作者:
Huang, Yan
;
Liu, Tao
;
Wang, Dandan
;
Wang, Xin
;
Li, Ran
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Isoproterenol
Calmodulin kinase II inhibitor
IL-Ca
Kinetics of L-type calcium channels
Ca2+ transient
Interleukin-1β in intervertebral disk degeneration
期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 262-272
作者:
Yang, Wei
;
Yu, Xiao-Hua
;
Wang, Cheng
;
He, Wen-Si
;
Zhang, Shu-Jun
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/27
IDD
intervertebral disk degeneration
IL-1
interleukin-1
IVD
intervertebral disk
ECM
extracellular matrix
LBP
low back pain
MMPs
matrix metalloproteinases
NP
nucleus pulposus
AF
annulus fibrosus
Col II
type II collagen
Col I
type I collagen
NTP
N-terminal peptide
NLS
nuclear localization sequence
IL-1RII
IL-1 receptor type II
TLRs
Toll-like receptors
IL-1RI
IL-1 receptor type I
IL-1RAcP
IL-1 receptor accessory protein
TIR
Toll-like/IL-1 receptor
MyD88
myeloid differentiation factor 88
TNF
tumor necrosis factor
NF-κB
nuclear factor-kappa B
MAPK
mitogen-activated protein kinase
IL-1Ra
IL-1 receptor antagonist
IFN-γ
interferon-γ
CCL
CC chemokine ligand
CXCL
CX chemokine ligand
ADAMTSs
a disintegrin and metalloprotease with thrombospondin motifs
TIMPs
tissues inhibitors of metalloproteinases
VEGF
vascular endothelial growth factor
NGF
nerve growth factor
BDNF
brain-derived neurotrophic factor
ROS
reactive oxygen species
SOD
superoxide dismutase
CAT
catalase
miRNAs
microRNAs
MSCs
mesenchymal stem cells
PRP
platelet-rich plasma
IL-1
IDD
Inflammatory responses
Angiogenesis
Apoptosis
Interleukin-1β in intervertebral disk degeneration
期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 262-272
作者:
WeiYang
;
Xiao-HuaYu
;
ChengWang
;
Wen-SiHe
;
Shu-JunZhang
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/27
IDD
intervertebral disk degeneration
IL-1
interleukin-1
IVD
intervertebral disk
ECM
extracellular matrix
LBP
low back pain
MMPs
matrix metalloproteinases
NP
nucleus pulposus
AF
annulus fibrosus
Col II
type II collagen
Col I
type I collagen
NTP
N-terminal peptide
NLS
nuclear localization sequence
IL-1RII
IL-1 receptor type II
TLRs
Toll-like receptors
IL-1RI
IL-1 receptor type I
IL-1RAcP
IL-1 receptor accessory protein
TIR
Toll-like/IL-1 receptor
MyD88
myeloid differentiation factor 88
TNF
tumor necrosis factor
NF-κB
nuclear factor-kappa B
MAPK
mitogen-activated protein kinase
IL-1Ra
IL-1 receptor antagonist
IFN-γ
interferon-γ
CCL
CC chemokine ligand
CXCL
CX chemokine ligand
ADAMTSs
a disintegrin and metalloprotease with thrombospondin motifs
TIMPs
tissues inhibitors of metalloproteinases
VEGF
vascular endothelial growth factor
NGF
nerve growth factor
BDNF
brain-derived neurotrophic factor
ROS
reactive oxygen species
SOD
superoxide dismutase
CAT
catalase
miRNAs
microRNAs
MSCs
mesenchymal stem cells
PRP
platelet-rich plasma
IL-1
IDD
Inflammatory responses
Angiogenesis
Apoptosis
MicroRNAs: New players in intervertebral disc degeneration
期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 333-341
作者:
Wang, Cheng
;
Wang, Wen-Jun
;
Yan, Yi-Guo
;
Xiang, Yong-Xiao
;
Zhang, Jian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/27
IVD
intervertebral disc
NP
nucleus pulposus
AF
annulus fibrosus
CEPs
cartilaginous endplates
IDD
intervertebral disc degeneration
ECM
extracellular matrix
miRNAs
microRNAs
RNA pol
RNA polymerase
DGCR8
DiGeorge syndrome critical gene 8
Exp 5
exportin 5
TRBP
transactivating response RNA-binding protein
RISC
RNA-induced silencing complex
Ago
Argonaute
PI3K
phosphoinositide 3-kinase
MAPK
mitogen-activated protein kinase
TGF-β
transforming growth factor-β
PDGF
platelet-derived growth factor
IGF
insulin-like growth factor
EGF
epidermal growth factor
CDKI1B
cyclin-dependent kinase inhibitor 1B
TNF-α
tumor necrosis factor-α
FADD
Fas-associated death domain-containing protein
Col II
type II collagen
Col I
type I collagen
MMPs
matrix metalloproteinases
ADAMTSs
a disintegrin and metalloprotease with thrombospondin motifs
Col I
type I collagen
Col II
type II collagen
FGF2
fibroblast growth factor 2
FGFR
fibroblast growth factor receptor
IL-1β
interleukin-1β
NGF
nerve growth factor
HOXD10
homeobox D10
MiRNAs
IDD
NP cells
Apoptosis
Cell proliferation
5TNF-alpha and IL-1 beta Neutralization Ameliorates Angiotensin II-Induced Cardiac Damage in Male Mice
期刊论文
ENDOCRINOLOGY, 2014, 卷号: 155, 期号: 7, 页码: 2677-2687
作者:
Wang, Yueli
;
Li, Yulin
;
Wu, Yina
;
Jia, Lixin
;
Wang, Jijing
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2014/11/02
TUMOR-NECROSIS-FACTOR
CORNEAL EPITHELIAL-CELLS
TARGET ORGAN DAMAGE
FACTOR-ALPHA
TNF-ALPHA
HEART-FAILURE
ENDOTHELIAL-CELLS
MONOCYTE
ADHESION
HYPERTENSION ROLE
IL-1 PATHWAYS
IFN-gamma and its receptors in a reptile reveal the evolutionary conservation of type II IFNs in vertebrates
期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2013, 卷号: 41, 期号: 4, 页码: 587-596
作者:
Chen, Shan Nan
;
Huang, Bei
;
Zhang, Xiao Wen
;
Li, Ye
;
Zhao, Li Juan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2014/01/24
IFN-gamma
IFNG
IFNGR1
IFNGR2
Lizard
树鼩干扰素系统的基本构成和分子特征研究:全基因组序列分析、基因克隆和相关实验验证
学位论文
硕士, 北京: 中国科学院研究生院, 2013
作者:
李明利
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2013/06/18
干扰素
树鼩
全基因组分析
基因预测
Hydrodynamics-based delivery of an interleukin-1 receptor II fusion gene ameliorates rat autoimmune myocarditis by inhibiting IL-1 and Th17 cell polarization
期刊论文
http://dx.doi.org/10.3892/ijmm.2013.1276, 2013
Chang, He
;
Wang, Yan
;
Wue, Weiyin
;
Lie, Gang
;
Hanawa, Haruo
;
Zou, Jun
;
常贺
;
王焱
;
邹军
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/07/22
NAKED PLASMID DNA
RHEUMATOID-ARTHRITIS
POSSIBLE MECHANISM
EXPRESSION
ANTAGONIST
FAMILY
LYMPHOCYTES
ANAKINRA
DISEASE
CLONING
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