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浏览/检索结果: 共7条，第1-7条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells 期刊论文 ONCOIMMUNOLOGY, 2021, 卷号: 10, 期号: 1, 页码: 13 作者:  Fan, Dandan;  Yue, Qi;  Chen, Jian;  Wang, Cong;  Yu, Ruilin 收藏  |  浏览/下载：24/0  |  提交时间：2021/08/17 Wnt/beta-catenin  IDH1-wildtype glioblastoma  Microglia  Phenotypic polarization   Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening 期刊论文 FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11 作者:  Wang, Yuwei;  Tang, Shuai;  Lai, Huanling;  Jin, Ruyi;  Long, Xu 收藏  |  浏览/下载：48/0  |  提交时间：2020/12/24 IDH1  gliomas  molecular docking  virtual screening  docking-based virtual screening   Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 5 作者:  Hu, Chujiao;  Zuo, Yu;  Liu, Jingqiu;  Xu, Heng;  Liao, Weike 收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01 Licochalcone A  Mutant IDH1  Selective inhibitor   Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants 期刊论文 CANCER SCIENCE, 2019, 页码: 9 作者:  Gao, Mingzhao;  Zhu, Hongmei;  Fu, Li;  Li, Yun;  Bao, Xubin 收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01 AG-221  IDH2  leukemia  R140Q  R172K   Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236 作者:  Duan, Zhe;  Liu, Jingqiu;  Niu, Liping;  Wang, Jun;  Feng, Mingqian 收藏  |  浏览/下载：55/0  |  提交时间：2020/07/01 IDH1 mutation  High-throughput screening  Pan-inhibitor  2-HG  Gliomas   Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3808-3812 作者:  Zheng, Qiangang;  Chen, Ziqi;  Wan, Huixin;  Tang, Shuai;  Ye, Yan 收藏  |  浏览/下载：234/0  |  提交时间：2019/01/08 IDH1 inhibitor  Imidazole cyclopropyl amine  Structure-based rational design   Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5262-5266 作者:  Zheng, Qiangang;  Tang, Shuai;  Fu, Xianlei;  Chen, Ziqi;  Ye, Yan 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 IDH1 inhibitor  Indane amide  Structure-based rational design