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上海药物研究所 [61]
复旦大学上海医学院 [27]
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Potential adverse outcome pathways with hazard identification of organophosphate esters
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 851, 页码: 13
作者:
Wang, Xiaoqing
;
Li, Fei
;
Teng, Yuefa
;
Ji, Chenglong
;
Wu, Huifeng
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/01/11
Organophosphate esters (OPEs)
Network-centric analysis
Risk assessment
Adverse outcome pathway
Quantitative weight of evidence
Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapy
期刊论文
STEM CELL RESEARCH & THERAPY, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:
Ma, Chen
;
Zhang, Ludi
;
He, Ting
;
Cao, Huiying
;
Ren, Xiongzhao
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/12/01
Raman spectroscopy
Cell therapy
Identification
Proliferating human hepatocytes
Dedifferentiation
Survival-Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah(-/-)Rag2(-/-)IL2rg(-/-) Rats
期刊论文
ADVANCED SCIENCE, 2021, 页码: 14
作者:
Zhang, Ludi
;
Ge, Jian-Yun
;
Zheng, Yun-Wen
;
Sun, Zhen
;
Wang, Chenhua
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
bioreactor
humanized liver
liver xeno-repopulation
pharmacological study
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Wu, Ya-li
;
Xue, Ya-ru
;
Guo, Zi-tao
;
Chen, Zhen-dong
;
Ge, Xin-yu
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
furmonertinib (alflutinib
AST2818)
quantitative proteomics
sandwich-cultured human hepatocytes
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:
Qiao, Shida
;
Feng, Sisi
;
Wu, Zhitao
;
He, Ting
;
Ma, Chen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
Effects of dibutyl phthalate on lipid metabolism in liver and hepatocytes based on PPAR alpha/SREBP-1c/FAS/GPAT/AMPK signal pathway
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 149
作者:
Zhang, Wang
;
Li, Jing-Ya
;
Wei, Xiao-Chen
;
Wang, Qian
;
Yang, Ji-Yang
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/04/26
DBP
PPAR alpha
AMPK
Lipid metabolism
Liver function
Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism
期刊论文
NATURE METABOLISM, 2021, 页码: 31
作者:
Xu, Yanyong
;
Li, Yuanyuan
;
Jadhav, Kavita
;
Pan, Xiaoli
;
Zhu, Yingdong
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/05/24
Chemerin reverses the malignant phenotype and induces differentiation of human hepatoma SMMC7721 cells
期刊论文
ARCHIVES OF PHARMACAL RESEARCH, 2021, 卷号: 44, 期号: 2
作者:
Li, Ming
;
Sun, Pengcheng
;
Dong, Kaikai
;
Xin, Ye
;
TaiLulu, Aslee
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/11/18
Chemerin
Human hepatic carcinoma SMMC7721 cells
Cell proliferation
Malignant phenotype
Cell differentiation
Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells
期刊论文
CELL REPORTS, 2020, 卷号: 33, 期号: 10, 页码: 24
作者:
Feng, Sisi
;
Wu, Jiaying
;
Qiu, Wei-Lin
;
Yang, Li
;
Deng, Xiaogang
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
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