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Design, synthesis and biological evaluation of 3-hydroxyquinazoline-2,4(1H, 3H)-diones as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and integrase 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 17, 页码: 3836-3845
作者:  Gao, Ping;  Cheng, Xiqiang;  Sun, Lin;  Song, Shu;  Alvarez, Mar
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11
Update on Recent Developments in Small Molecular HIV-1 RNase H Inhibitors (2013-2016): Opportunities and Challenges 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2018, 卷号: 25, 期号: 14, 页码: 1682-1702
作者:  Wang, Xueshun;  Gao, Ping;  Menendez-Arias, Luis;  Liu, Xinyong;  Zhan, Peng
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/11
5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 155, 页码: 714-724
作者:  Sun, Lin;  Gao, Ping;  Dong, Guanyu;  Zhang, Xujie;  Cheng, Xiqiang
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/11
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 125, 页码: 1051-1063
作者:  Zhang, Feng-Hua;  Debnath, Bikash;  Xu, Zhong-Liang;  Yang, Liu-Meng;  Song, Li-Rui
收藏  |  浏览/下载:13/0  |  提交时间:2019/01/08
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 125, 期号: X, 页码: 1051-1063
作者:  Zhang FH;  Debnath B;  Zheng YT;  Neamati N[*];  Long YQ[*]
收藏  |  浏览/下载:72/0  |  提交时间:2016/11/07
Probing Origin of Binding Difference of inhibitors to MDM2 and MDMX by Polarizable Molecular Dynamics Simulation and QM/MM-GBSA Calculation 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Chen, Jianzhong;  Wang, Jinan;  Zhang, Qinggang;  Chen, Kaixian;  Zhu, Weiliang
收藏  |  浏览/下载:20/0  |  提交时间:2019/01/08
Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors 期刊论文
Bioorganic and Medicinal Chemistry Letters, 2013, 卷号: 23, 期号: 24, 页码: 6593-6597
作者:  Chen,X.;  Liu,X.;  Meng,Q.;  Wang,D.;  Liu,H.
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/23
Computational Studies of Difference in Binding Modes of Peptide and Non-Peptide Inhibitors to MDM2/MDMX Based on Molecular Dynamics Simulations 期刊论文
international journal of molecular sciences, 2012, 卷号: 13, 期号: 2, 页码: 2176-2195
作者:  Chen, Jianzhong;  Zhang, Dinglin;  Zhang, Yuxin;  Li, Guohui
收藏  |  浏览/下载:18/0  |  提交时间:2015/11/13
The Development of HEPT-Type HIV Non-Nucleoside Reverse Transcriptase Inhibitors and Its Implications for DABO Family 期刊论文
CURRENT PHARMACEUTICAL DESIGN, 2012, 卷号: 18, 期号: 27, 页码: 4165-4186
作者:  Chen, Wenmin;  Zhan, Peng;  Wu, Jingde;  Li, Zhenyu;  Liu, Xinyong
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/23
Highly Potent and Dual-acting Pyrimidinedione Inhibitors of HIV-1 Possess a High Genetic Barrier to Resistance 会议论文
22nd International Conference on Antiviral Research, MAY 03-07, 2009
作者:  Liu, Xinyong;  Zhan, Peng;  Pannecouque, Christophe;  De Clercq, Erik
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/31


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