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上海药物研究所 [9]
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Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly: Recent Advances and Perspectives
期刊论文
ACS INFECTIOUS DISEASES, 2019, 卷号: 5, 期号: 5, 页码: 713-724
作者:
Yang, Li
;
Liu, Feifei
;
Tong, Xiankun
;
Hoffmann, Daniel
;
Zuo, Jianping
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
hepatitis B virus
HBV core protein
HBcAg
capsid assembly
capsid assembly modulators (CAMs)
antiviral therapy
clinical trials
Rna-binding motif protein 24 (rbm24) is involved in pregenomic rna packaging by mediating interaction between hepatitis b virus polymerase and the epsilon element
期刊论文
Journal of virology, 2019, 卷号: 93, 期号: 6, 页码: 17
作者:
Yao, Yongxuan
;
Yang, Bo
;
Chen, Yingshan
;
Wang, Hui
;
Hu, Xue
收藏
  |  
浏览/下载:501/0
  |  
提交时间:2019/05/08
Hbv polymerase
Hbv epsilon element
Rbm24
Interaction
Pgrna packaging
Naturally occurring core protein mutations compensate for the reduced replication fitness of a lamivudine-resistant HBV isolate
期刊论文
ANTIVIRAL RESEARCH, 2019, 卷号: 165
作者:
Zhang, Yongmei
;
Zhang, Hu
;
Zhang, Junjie
;
Zhang, Jiming
;
Guo, Haitao
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
Hepatitis B virus
Drug resistance
Replication fitness
Capsid assembly
Upregulation of hbv transcription by sodium taurocholate cotransporting polypeptide at the postentry step is inhibited by the entry inhibitor myrcludex b
期刊论文
Emerging microbes & infections, 2018, 卷号: 7, 页码: 14
作者:
Zhao, Kaitao
;
Liu, Shuhui
;
Chen, Yingshan
;
Yao, Yongxuan
;
Zhou, Ming
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2019/05/08
RBM24 stabilizes hepatitis B virus pregenomic RNA but inhibits core protein translation by targeting the terminal redundancy sequence
期刊论文
EMERGING MICROBES & INFECTIONS, 2018, 卷号: 7, 页码: 14
作者:
Wang, Yun
;
Zhao, Kaitao
;
Yuan, Yifei
;
Chen, Yingshan
;
Zhang, Zhenhua
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2018/12/29
Mechanisms and effects on hbv replication of the interaction between hbv core protein and cellular filamin b
期刊论文
Virologica sinica, 2018, 卷号: 33, 期号: 2, 页码: 162-172
作者:
Li, Yilin
;
Sun, Yishuang
;
Sun, Fuyun
;
Hua, Rong
;
Li, Chenlin
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/05/08
Filamin b
Core
Hbv replication
Immunization with lentiviral vector-modified dendritic cells encoding ubiquitinated hepatitis B core antigen promotes Th1 differentiation and antiviral immunity by enhancing p38 MAPK and JNK activation in HBV transgenic mice
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 18, 期号: 5, 页码: 4691-4699
作者:
Dai, Shenglan[1]
;
Chen, Xiaohua[2]
;
Yu, Yongsheng[3]
;
Zang, Guoqing[4]
;
Tang, Zhenghao[5]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/24
dendritic cell
hepatitis B core antigen
lentiviral vector
P38-mitogen-activated protein kinase/c-Jun N-terminal kinase signaling pathway
ubiquitin
Mechanisms and Effects on HBV Replication of the Interaction between HBV Core Protein and Cellular Filamin B
期刊论文
VIROLOGICA SINICA, 2018, 卷号: 33, 期号: 2
作者:
Li, Yilin
;
Sun, Yishuang
;
Sun, Fuyun
;
Hua, Rong
;
Li, Chenlin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Filamin B
Core
HBV replication
Small Molecule Inhibitors of Hepatitis B Virus Nucleocapsid Assembly: A New Approach to Treat Chronic HBV Infection
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2018, 卷号: 25, 期号: 7, 页码: 802-813
作者:
Yang, Li
;
Lu, Mengji
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Hepatitis B virus
core protein
capsid assembly
capsid assembly modulator
misassembly
antiviral therapy
Naturally occurring basal core promoter A1762T/G1764A dual mutations increase the risk of HBV-related hepatocellular carcinoma: a meta-analysis
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 11
作者:
Yang, Zongguo
;
Zhuang, Liping
;
Lu, Yunfei
;
Xu, Qingnian
;
Tang, Bozong
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
hepatitis B virus X protein
hepatocellular carcinoma
basal core promoter
mutation
A1762T/G1764A
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