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Crosstalk between CYP2E1 and PPAR alpha substrates and agonists modulate adipose browning and obesity
期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2224-2238
作者:
Zhang, Youbo
;
Yan, Tingting
;
Wang, Tianxia
;
Liu, Xiaoyan
;
Hamada, Keisuke
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/07/19
CYP2E1
PPAR alpha
FGF21
Metabolic enzyme
Nuclear receptor
Obesity
Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:
Lu, Dasheng
;
Liu, Yameng
;
Luo, Yuhong
;
Zhao, Jie
;
Feng, Chao
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  |  
浏览/下载:49/0
  |  
提交时间:2022/01/18
Fatty acid oxidation
Acylcarnitines
FXR
FGF15/19
PGC1 alpha
Transcriptomics
Metabolomics
Research on Orientation of Basic Fibroblast Growth Factor with Magnetic Nanoparticles (MNPs) on Regeneration and Recovery of Rats? Dampened Skeletal Muscle and Expressed Level of Matrix Metalloproteinase
期刊论文
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2022, 卷号: 18
作者:
Jin, Bicheng
;
Zhang, Lei
;
Wang, Xiaowei
;
Jin, Dongfang
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  |  
浏览/下载:9/0
  |  
提交时间:2022/12/23
MNP
bFGF Orientation
Skeletal Muscle Contusion
Skeletal Muscle Regeneration
Recovery
Level of MMPS
Activating Adenosine Monophosphate-Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice
期刊论文
HEPATOLOGY, 2021, 卷号: 73, 期号: 6, 页码: 2206-2222
作者:
Lin, Qian
;
Huang, Zhifeng
;
Cai, Genxiang
;
Fan, Xia
;
Yan, Xiaoqing
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/08/17
Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-beta RI/Smad Signaling
期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 6, 页码: 19
作者:
Luo, Xin
;
Deng, Qiangqiang
;
Xue, Yaru
;
Zhang, Tianwei
;
Wu, Zhitao
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/06/11
pulmonary fibrosis
bleomycin
magnesium lithospermate B
transforming growth factor-beta
Smad signaling
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:
Wu, Xiaowei
;
Dai, Mengdi
;
Cui, Rongrong
;
Wang, Yulan
;
Li, Chunpu
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  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Tyrosine kinase
Covalent FGFR inhibitors
Virtual screening
Pyrazolo[3,4-d] pyridazinone
Structure-activity relationships
Antitumor efficacy
Dynamic folding modulation generates FGF21 variant against diabetes
期刊论文
EMBO REPORTS, 2021, 卷号: 22
作者:
Zhu, Lei
;
Zhao, Hongxin
;
Liu, Juanjuan
;
Cai, Hao
;
Wu, Bo
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  |  
浏览/下载:24/0
  |  
提交时间:2021/08/30
anti‐
diabetes
disulfide bond mutation
FGF21
folding dynamics
NMR
A pentapeptide enabled AL3810 liposome-based glioma-targeted therapy with immune opsonic effect attenuated
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 1, 页码: 283-299
作者:
Li, Jinyang
;
Lu, Jiasheng
;
Guo, Haiyan
;
Zhou, Jianfen
;
Wang, Songli
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
Liposome
mn
c(RGDyK)
Immune opsonization
Immunogenicity
Anti-glioma efficacy
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
Toxicity of silver nanoparticles on wound healing: A case study of zebrafish fin regeneration model
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 717, 页码: 1-9
作者:
Pang, Shaochen
;
Gao, Yue
;
Wang, Fengbang
;
Wang, Yuanyuan
;
Cao, Mengxi
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2021/09/14
AgNPs
Epithelialization
Proliferation
Neutrophil
Reactive oxygen species
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