CORC

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CORC

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Crosstalk between CYP2E1 and PPAR alpha substrates and agonists modulate adipose browning and obesity 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2224-2238
作者:  Zhang, Youbo;  Yan, Tingting;  Wang, Tianxia;  Liu, Xiaoyan;  Hamada, Keisuke
收藏  |  浏览/下载：25/0  |  提交时间：2022/07/19
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:  Wu, Xiaowei;  Dai, Mengdi;  Cui, Rongrong;  Wang, Yulan;  Li, Chunpu
收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24
A pentapeptide enabled AL3810 liposome-based glioma-targeted therapy with immune opsonic effect attenuated 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 1, 页码: 283-299
作者:  Li, Jinyang;  Lu, Jiasheng;  Guo, Haiyan;  Zhou, Jianfen;  Wang, Songli
收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24
Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488
作者:  Wang, Yulan;  Dai, Yang;  Wu, Xiaowei;  Li, Fei;  Liu, Bo
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01
Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and and in vivo study 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 2, 页码: 351-368
作者:  Wei, Peng;  Liu, Bo;  Wang, Ruifeng;  Gao, Yinglei;  Li, Lanlan
收藏  |  浏览/下载：103/0  |  提交时间：2020/07/01
Dual-mixed/CMC model for screening target components from traditional Chinese medicines simultaneously acting on EGFR & FGFR4 receptors. 期刊论文
Talanta, 2019, 卷号: 192, 页码: 248-254
作者:  Fu Jia;  Lv Yanni;  Jia Qianqian;  Lin Yuanyuan;  Han Shengli
收藏  |  浏览/下载：17/0  |  提交时间：2019/11/19
discoveryofaseriesofdimethoxybenzenefgfrinhibitorswith5hpyrrolo23bpyrazinescaffoldstructureactivityrelationshipcrystalstructuralcharacterizationandinvivostudy 期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 2, 页码: 351
作者:  Wei Peng;  Liu Bo;  Wang Ruifeng;  Gao Yinglei;  Li Lanlan
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01
c11anovelfibroblastgrowthfactorreceptor1fgfr1inhibitorsuppressesbreastcancermetastasisandangiogenesis 期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 6, 页码: 823
作者:  Chen Zhuo;  Tong Linjiang;  Tang Baiyou;  Liu Hongyan;  Wang Xin
收藏  |  浏览/下载：5/0  |  提交时间：2020/07/01
The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors 期刊论文
Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842
作者:  Wang, Xinyi;  Ai, Jing;  Liu, Hongyan;  Peng, Xia;  Chen, Hui
收藏  |  浏览/下载：135/0  |  提交时间：2019/01/08
C11, a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, suppresses breast cancer metastasis and angiogenesis 期刊论文
Acta pharmacologica Sinica, 2018
作者:  Chen, Zhuo;  Tong, Lin-Jiang;  Tang, Bai-You;  Liu, Hong-Yan;  Wang, Xin
收藏  |  浏览/下载：101/0  |  提交时间：2019/01/08

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