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浏览/检索结果:
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Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:
Lu, Dasheng
;
Liu, Yameng
;
Luo, Yuhong
;
Zhao, Jie
;
Feng, Chao
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/01/18
Fatty acid oxidation
Acylcarnitines
FXR
FGF15/19
PGC1 alpha
Transcriptomics
Metabolomics
Binding Pattern Reconstructions of FGF-FGFR Budding-Inducing Signaling in Reef-Building Corals
期刊论文
FRONTIERS IN PHYSIOLOGY, 2022, 卷号: 12, 页码: 12
作者:
Guo, Zhuojun
;
Liao, Xin
;
Chen, J. -Y.(陈均远)
;
He, Chunpeng
;
Lu, Zuhong
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  |  
浏览/下载:28/0
  |  
提交时间:2022/02/24
reef-building coral
budding reproduction
receptor tyrosine kinase
full-length transcriptome
FGF-FGFR binding models
Cancer-Associated Fibroblast-Derived Interleukin-8 Promotes Ovarian Cancer Cell Stemness and Malignancy Through the Notch3-Mediated Signaling
期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9
作者:
Ji, Zhaodong
;
Tian, Wenjuan
;
Gao, Wen
;
Zang, Rongyu
;
Wang, Huaying
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/08/30
IL-8
tumor stemness
epithelial ovarian cancer
cancer-associated ovarian fibroblasts
Notch3 signal pathway
Activating Adenosine Monophosphate-Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice
期刊论文
HEPATOLOGY, 2021, 卷号: 73, 期号: 6, 页码: 2206-2222
作者:
Lin, Qian
;
Huang, Zhifeng
;
Cai, Genxiang
;
Fan, Xia
;
Yan, Xiaoqing
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  |  
浏览/下载:34/0
  |  
提交时间:2021/08/17
Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-beta RI/Smad Signaling
期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 6, 页码: 19
作者:
Luo, Xin
;
Deng, Qiangqiang
;
Xue, Yaru
;
Zhang, Tianwei
;
Wu, Zhitao
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  |  
浏览/下载:70/0
  |  
提交时间:2021/06/11
pulmonary fibrosis
bleomycin
magnesium lithospermate B
transforming growth factor-beta
Smad signaling
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:
Wu, Xiaowei
;
Dai, Mengdi
;
Cui, Rongrong
;
Wang, Yulan
;
Li, Chunpu
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  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Tyrosine kinase
Covalent FGFR inhibitors
Virtual screening
Pyrazolo[3,4-d] pyridazinone
Structure-activity relationships
Antitumor efficacy
A pentapeptide enabled AL3810 liposome-based glioma-targeted therapy with immune opsonic effect attenuated
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 1, 页码: 283-299
作者:
Li, Jinyang
;
Lu, Jiasheng
;
Guo, Haiyan
;
Zhou, Jianfen
;
Wang, Songli
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  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
Liposome
mn
c(RGDyK)
Immune opsonization
Immunogenicity
Anti-glioma efficacy
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
RepSox, a small molecule inhibitor of the TGF beta receptor, induces brown adipogenesis and browning of white adipocytes
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1523-1531
作者:
Tu, Wan-zhi
;
Fu, Yan-bin
;
Xie, Xin
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/07/01
RepSox
brown adipogenesis
TGF-beta receptor
TGF-beta inhibitor
adipocyte
differentiation
Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488
作者:
Wang, Yulan
;
Dai, Yang
;
Wu, Xiaowei
;
Li, Fei
;
Liu, Bo
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
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