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New and effective EGFR-targeted fluorescence imaging technology for intraoperative rapid determination of lung cancer in freshly isolated tissue
期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2022, 页码: 14
作者:
Li, Changjian
;
Mi, Jiahui
;
Wang, Yueqi
;
Zhang, Zeyu
;
Guo, Xiaoyong
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/11/14
Intraoperative imaging technology
Lung cancer
Fluorescence-labeled antibody probe
Epidermal growth factor receptor
Surgical tumor resection
Targeting KRAS mutant cancers: from druggable therapy to drug resistance
期刊论文
MOLECULAR CANCER, 2022, 卷号: 21
作者:
Zhu, Chunxiao
;
Guan, Xiaoqing
;
Zhang, Xinuo
;
Luan, Xin
;
Song, Zhengbo
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
KRAS mutations
Druggable
Resistance
Combination therapy
A novel co-targeting strategy of EGFR/SEC61G for multi-modality fluorescence/MR/photoacoustic imaging of glioblastoma
期刊论文
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2022, 卷号: 40, 页码: 11
作者:
Huang, Qi
;
Wang, Kun
;
Wanggou, Siyi
;
Tian, Jie
;
Li, Xuejun
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/07/25
Glioblastoma
Multi-modality
Molecular imaging
Dual-target
Theranostic
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:
Tao, Zhonghua
;
Liu, Jianxia
;
Li, Ting
;
Xu, Hong
;
Chen, Kai
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/01/10
receptor tyrosine kinase
gene fusion
genomic rearrangments
breast cancer
next-generation sequencing
Discovery of Cyclic Peptidomimetic Ligands Targeting the Extracellular Domain of EGFR
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 11219-11228
作者:
Zheng, Mengmeng
;
Li, Chunpu
;
Zhou, Mi
;
Jia, Ru
;
Cai, Gang
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/11/04
MD2 blockage prevents the migration and invasion of hepatocellular carcinoma cells via inhibition of the EGFR signaling pathway
期刊论文
JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2021
作者:
Qi, Yajun
;
Fang, Qilu
;
Li, Qinglin
;
Ding, Haiying
;
Shu, Qi
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/09/06
Hepatocellular carcinoma (HCC)
myeloid differentiation protein 2 (MD2)
epidermal growth factor receptor (EGFR)
migration
invasion
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells
期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:
Zhang, Mi
;
Quan, Haitian
;
Fu, Li
;
Li, Yun
;
Fu, Haoyu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/05/24
EGFR‐
mutant non‐
small cell lung cancer
famitinib
HS‐
10296
multi‐
targeted tyrosine kinase inhibitor
third‐
generation EGFR inhibitor
Biomimetic codelivery overcomes osimertinib-resistant NSCLC and brain metastasis via macrophage-mediated innate immunity
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 329, 页码: 1249-1261
作者:
Zhao, Pengfei
;
Zhang, Jiaxin
;
Wu, Aihua
;
Zhang, Meng
;
Zhao, Yuge
收藏
  |  
浏览/下载:109/0
  |  
提交时间:2021/05/24
Brain targeting delivery
Tumor-associated macrophage
Osimertinib resistance
Brain metastasis
Innate immunity
Combination therapy
Construction of a novel bispecific fusion protein to enhance targeting for pancreatic cancer imaging
期刊论文
BIOMATERIALS, 2020, 期号: 255, 页码: 120161
作者:
Wang, Qian
;
Yan, Hao
;
Wang, Zihua
;
Li, Zhangfu
;
Li, Dan
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/09/07
Bispecific targeting
Fusion protein
Antibody
Molecular imaging
Pancreatic cancer
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