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上海药物研究所 [64]
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厦门大学 [7]
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期刊论文 [163]
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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Mechanism investigation for ultra-efficient photocatalytic water disinfection based on rational design of indirect Z-scheme heterojunction black phosphorus QDs/Cu2O nanoparticles
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2022, 卷号: 424
作者:
Luo, SJ
;
Liu, RX
;
Zhang, XX
;
Chen, R
;
Yan, MM
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  |  
浏览/下载:14/0
  |  
提交时间:2022/12/02
Innovative Synthesis of PANI/Cu2O Nanocomposite and Its Antibacterial Properties**
期刊论文
CHEMISTRYSELECT, 2021, 卷号: 6, 期号: 47, 页码: 13636-13641
作者:
Zhang, Mengmeng
;
Han, Sha
;
Niu, Xiaohui
;
Li, Hongxia
;
Zhang, Deyi
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/03/01
Antibiotics
Cuprous oxide nanoparticles
Drug resistant
Nanocomposites
Polyaniline
Antifungal azoles and azole resistance in the environment: current status and future perspectives-a review
期刊论文
REVIEWS IN ENVIRONMENTAL SCIENCE AND BIO-TECHNOLOGY, 2021, 页码: 31
作者:
Assress, Hailemariam Abrha
;
Selvarajan, Ramganesh
;
Nyoni, Hlengilizwe
;
Mamba, Bhekie B.
;
Msagati, Titus A. M.
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  |  
浏览/下载:31/0
  |  
提交时间:2021/11/16
Occurrence
Azole antifungal drugs
Azole resistance
Future perspectives
Fungi
Environment
Design, Synthesis, and Biological Evaluation of Novel Pyrimido[4,5-b]indole Derivatives Against Gram-Negative Multidrug-Resistant Pathogens
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8644-8665
作者:
Kong, Qidi
;
Pan, Wei
;
Xu, Heng
;
Xue, Yaru
;
Guo, Bin
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  |  
浏览/下载:38/0
  |  
提交时间:2021/08/17
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:
Liu, Xiaohua
;
Zhang, Yu
;
Li, Yalei
;
Wang, Juan
;
Ding, Huaqian
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/05/24
Medulloblastoma
Hedgehog signaling
pathway
Drug resistance
GLI
BRD4
Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:
Wang, Yu-xiang
;
Zhang, Xu
;
Ma, Qing-yang
;
Hu, Lan-dian
;
Zhang, Xi
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  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Out-of-the-Box Nanocapsules Packed with On-Demand Hydrophobic Anticancer Drugs for Lung Targeting, Esterase Triggering, and Synergy Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2021
作者:
Zhao, Di
;
Jiang, Kai
;
Wang, Yuqi
;
Cheng, Jin
;
Mo, Fangli
收藏
  |  
浏览/下载:122/0
  |  
提交时间:2021/03/15
controllable esterase response
high loading efficiency
lung targeting
multi-drug resistance
universal drug encapsulation
A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe
期刊论文
Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1
作者:
Hu,Liangning
;
Li,Bo
;
Chen,Gege
;
Song,Dongliang
;
Xu,Zhijian
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2020/07/01
Multiple myeloma
Drug-resistance
DNA damage response
Cell cycle
Discovery of 6 '-chloro-N-methyl-5 '-(phenylsulfonamido)-[3,3 '-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 188
作者:
Liang, Xiaofei
;
Jiang, Zongru
;
Huang, Zhenghui
;
Li, Feng
;
Chen, Cheng
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/11/26
PI4K kinase
Kinase inhibitor
Malaria
Blood stage
Liver stage
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