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科研机构
北京大学 [11]
上海药物研究所 [7]
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期刊论文 [33]
学位论文 [2]
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New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264
作者:
Tian, Qian-Ting
;
Ding, Chun-Yong
;
Song, Shan-Shan
;
Wang, Ying-Qing
;
Zhang, Ao
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Tanshinone-1
S222
S439
Anticancer targets
DNA topoisomerases
P53
Synthesis and antibacterial activity of C-2 or C-5 modified and D ring rejiggered canthin-6-one analogues
期刊论文
FOOD CHEMISTRY, 2018, 卷号: 253, 页码: 211-220
作者:
Dai, Jiangkun
;
Dan, Wenjia
;
Li, Nian
;
Wang, Ruixue
;
Zhang, Yao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Synthesis
Canthin-6-one analogues
Antibacterial
Structure-activity relationships
Cell membrane
DNA topoisomerases
PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner
期刊论文
JOURNAL OF VIROLOGY, 2018, 卷号: 92, 期号: 22
作者:
Xu, Wei
;
Ma, Chunqiang
;
Zhang, Qi
;
Zhao, Rong
;
Hu, Dan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
RING finger protein PJA1
SMC5/6 complex
DNA topoisomerases
hepatitis B virus
HBV
herpes simplex virus 1
HSV-1
episomal DNA
extrachromosomal DNA
host immune response
Screening for Natural Inhibitors of Topoisomerases I from Rhamnus davurica by Affinity Ultrafiltration and High-Performance Liquid Chromatography-Mass Spectrometry
期刊论文
FRONTIERS IN PLANT SCIENCE, 2017, 卷号: 8, 页码: 11
作者:
Chen, Guilin
;
Guo, Mingquan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2017/12/31
topoisomerases I
Rhamnus davurica
ultrafiltration
high performance liquid chromatography-mass spectrometry
flavonoids
Type IA topoisomerases can be "magicians" for both DNA and RNA in all domains of life
期刊论文
RNA BIOLOGY, 2017
Ahmad, Muzammil
;
Xu, Dongyi
;
Wang, Weidong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2017/12/03
FMRP
polyribosomes
topoisomerase
TDRD3
Top3
Top3
BLOOM-SYNDROME DISSOLVASOME
X-SYNDROME PROTEIN
ESCHERICHIA-COLI
MESSENGER-RNA
III-ALPHA
ESSENTIAL COMPONENT
CELLULAR ROLES
CIRCULAR RNAS
COMPLEX
TDRD3
Topoisomerase 3 beta is the major topoisomerase for mRNAs and linked to neurodevelopment and mental dysfunction
期刊论文
NUCLEIC ACIDS RESEARCH, 2017
Ahmad, Muzammil
;
Shen, Weiping
;
Li, Wen
;
Xue, Yutong
;
Zou, Sige
;
Xu, Dongyi
;
Wang, Weidong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2017/12/03
FRAGILE-X-SYNDROME
DNA TOPOISOMERASES
BINDING PROTEINS
III-BETA
SCHIZOPHRENIA
TOP3-BETA
FMRP
PERSPECTIVE
AUTISM
ROLES
Kinetic insights into the temperature dependence of DNA strand cleavage and religation by topoisomerase III from the hyperthermophile Sulfolobus solfataricus
期刊论文
SCIENTIFIC REPORTS, 2017
Zhang, Junhua
;
Pan, Bailong
;
Li, Zhimeng
;
Zhao, Xin Sheng
;
Huang, Li
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2017/12/03
INDUCED FLUORESCENCE ENHANCEMENT
CRYSTAL-STRUCTURE
PROTEIN
MECHANISM
MOLECULE
Identification of Bisindolylmaleimide IX as a potential agent to treat drug-resistant BCR-ABL positive leukemia
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 43, 页码: 69945-69960
作者:
Zhang, Xin
;
Jia, Deyong
;
Ao, Junping
;
Liu, Huijuan
;
Zang, Yi
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Bisindolylmaleimide IX
BCR-ABL
chronic myeloid leukemia (CML)
Novel synthetic acridine-based derivatives as topoisomerase Ⅰ inhibitors
期刊论文
2016, 2016
Bin Li
;
Chun-Mei Gao
;
Qin-Sheng Sun
;
Lu-Lu Li
;
Chun-Yan Tan
;
Hong-Xia Liu
;
Yu-Yang Jiang
;
Bin Li
;
Chun-Mei Gao
;
Qin-Sheng Sun
;
Lu-Lu Li
;
Chun-Yan Tan
;
Hong-Xia Liu
;
Yu-Yang Jiang
收藏
  |  
浏览/下载:5/0
RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animals
期刊论文
NUCLEIC ACIDS RESEARCH, 2016
Ahmad, Muzammil
;
Xue, Yutong
;
Lee, Seung Kyu
;
Martindale, Jennifer L.
;
Shen, Weiping
;
Li, Wen
;
Zou, Sige
;
Ciaramella, Maria
;
Debat, Helene
;
Nadal, Marc
;
Leng, Fenfei
;
Zhang, Hongliang
;
Wang, Quan
;
Siaw, Grace Ee-Lu
;
Niu, Hengyao
;
Pommier, Yves
;
Gorospe, Myriam
;
Hsieh, Tao-Shih
;
Tse-Dinh, Yuk-Ching
;
Xu, Dongyi
;
Wang, Weidong
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2017/12/03
X-SYNDROME PROTEIN
DNA TOPOISOMERASE
ESCHERICHIA-COLI
REVERSE GYRASE
CRYSTAL-STRUCTURE
CELL-LINES
COMPLEX
BINDING
GENOME
RELAXATION
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