CORC

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CORC

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Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy 期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:  Hua, Chen;  Shena, Lijuan;  Zoua, Fengming;  Wua, Yun;  Wanga, Beilei
收藏  |  浏览/下载：10/0  |  提交时间：2023/11/10
A positive feedback circuit comprising p21 and HIF-1 alpha aggravates hypoxia-induced radioresistance of glioblastoma by promoting Glut1/LDHA-mediated glycolysis 期刊论文
FASEB JOURNAL, 2022, 卷号: 36, 期号: 3
作者:  Jin, Xiaodong;  Kuang, Yanbei;  Li, Linying;  Li, Hongbin;  Zhao, Ting
收藏  |  浏览/下载：16/0  |  提交时间：2022/04/21
A positive feedback circuit comprising p21 and HIF-1 alpha aggravates hypoxia-induced radioresistance of glioblastoma by promoting Glut1/LDHA-mediated glycolysis 期刊论文
FASEB JOURNAL, 2022, 卷号: 36, 期号: 3, 页码: 14
作者:  Jin, Xiaodong;  Kuang, Yanbei;  Li, Linying;  Li, Hongbin;  Zhao, Ting
收藏  |  浏览/下载：20/0  |  提交时间：2022/04/11
Transcriptomic analysis reveals the role of FOUR LIPS in response to salt stress in rice 期刊论文
PLANT MOLECULAR BIOLOGY, 2022, 卷号: 110, 期号: 1-2, 页码: 37-52
作者:  Zhang, Chunxia;  Zhang, Jie;  Liu, Huichao;  Qu, Xiaoxiao;  Wang, Junxue
收藏  |  浏览/下载：0/0  |  提交时间：2024/03/07
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Protein degradation technology: a strategic paradigm shift in drug discovery 期刊论文
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 卷号: 14
作者:  Li, Haobin;  Dong, Jinyun;  Cai, Maohua;  Xu, Zhiyuan;  Cheng, Xiang-Dong
收藏  |  浏览/下载：31/0  |  提交时间：2021/11/01
Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition 期刊论文
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 6, 页码: 1929-1936
作者:  Gao, Jing;  Zhang, Hanwu;  Zhou, Fengqi;  Hou, Bo;  Chen, Meiwan
收藏  |  浏览/下载：17/0  |  提交时间：2021/08/17
Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 12
作者:  Lin, Tingting;  Li, Jiacheng;  Liu, Liping;  Li, Yuanqing;  Jiang, Hualiang
收藏  |  浏览/下载：70/0  |  提交时间：2021/05/24
Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury 期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 7, 页码: 925-941
作者:  Liu, Yanjun;  Li, Jiacheng;  Liao, Liping;  Huang, Heming;  Fan, Shijie
收藏  |  浏览/下载：21/0  |  提交时间：2021/08/17
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11
作者:  Qiu, Xiaqiu;  Li, Yuanqing;  Yu, Bin;  Ren, Jie;  Huang, Huidan
收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24
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