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清华大学 [8]
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南海海洋研究所 [2]
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期刊论文 [34]
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浏览/检索结果:
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Integrated Transcriptomics and Reverse Pharmacophore Mapping-based Network Pharmacology to Explore the Mechanisms of Natural Compounds against Doxorubicin-induced Cardiotoxicity
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2022, 卷号: 25
作者:
Zhu, Junfeng
;
Yi, Xiaojiao
;
Ding, Haiying
;
Zhong, Like
;
Fang, Luo
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
Doxorubicin-induced cardiotoxicity
natural compounds
mechanism of action
gene expression profile
bioinformatics
network pharmacology
Additive effects of variants of unknown significance in replication repair-associated DNA polymerase genes on mutational burden and prognosis across diverse cancers
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 卷号: 9
作者:
Ying, Jieer
;
Yang, Lin
;
Yin, Jiani C.
;
Xia, Guojie
;
Xing, Minyan
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/11/15
biomarkers
tumor
genetic markers
genome instability
Immunotherapy
translational medical research
Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer's disease
期刊论文
JOURNAL OF NEUROINFLAMMATION, 2021, 卷号: 18, 期号: 1, 页码: 14
作者:
Sun, Xiao-ying
;
Li, Ling-jie
;
Dong, Quan-Xiu
;
Zhu, Jie
;
Huang, Ya-ru
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/31
Alzheimer's disease
Tau pathology
Neurofibrillary tangles
Neuroinflammation
Synapse loss
Rutin
A combinatorial method to visualize the neuronal network in the mouse spinal cord: combination of a modified Golgi-Cox method and synchrotron radiation micro-computed tomography
期刊论文
HISTOCHEMISTRY AND CELL BIOLOGY, 2021, 页码: 13
作者:
Jiang, Liyuan
;
Cao, Yong
;
Yin, Xianzhen
;
Ni, Shuangfei
;
Li, Miao
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
SRμ
CT
Modified Golgi-Cox method
Spinal cord
Neuronal network
Three-dimension
Concentration optimization of combinatorial drugs using Markov chain-based models
期刊论文
BMC Bioinformatics, 2021, 卷号: 22, 期号: 1, 页码: 1-19
作者:
Ma S(马爽)
;
Dang D(党丹)
;
Wang WX(王文学)
;
Wang YC(王越超)
;
Liu LQ(刘连庆)
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/10/03
Combinatorial drug optimization
Markov chain
Transition probability
Stationary balance distribution
Combinatorial therapy
Upfront dose-reduced chemotherapy synergizes with immunotherapy to optimize chemoimmunotherapy in squamous cell lung carcinoma
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 卷号: 8, 期号: 2, 页码: 15
作者:
He, Xiran
;
Du, Yang
;
Wang, Zhijie
;
Wang, Xin
;
Duan, Jianchun
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/01/06
drug therapy
combination
immunotherapy
lung neoplasms
lymphocytes
tumor-infiltrating
translational medical research
Reynoutria Japonica from Traditional Chinese Medicine: A Source of Competitive Adenosine Deaminase Inhibitors for Anticancer
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2019, 卷号: 22, 期号: 2, 页码: 113-122
作者:
Zhang, Xin-Guo
;
Ma, Guo-Yan
;
Fei Kou
;
Liu, Wen-Jie
;
Sun, Qiao-Yun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/15
ADA inhibitors
Reynoutria japonica
cordycepin
lymphoproliferative disorders
anti-cancer therapy
traditional chinese medicine
Reynoutria Japonica from Traditional Chinese Medicine: A Source of Competitive Adenosine Deaminase Inhibitors for Anticancer
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2019, 卷号: 22, 期号: 2, 页码: 113-122
作者:
Zhang, Xin-Guo
;
Ma, Guo-Yan
;
Fei Kou
;
Liu, Wen-Jie
;
Sun, Qiao-Yun
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2022/03/01
ADA inhibitors
Reynoutria japonica
cordycepin
lymphoproliferative disorders
anti-cancer therapy
traditional chinese medicine
Characterization and heterologous expression of the neoabyssomicin/abyssomicin biosynthetic gene cluster from Streptomyces koyangensis SCSIO 5802
期刊论文
MICROBIAL CELL FACTORIES, 2018, 卷号: 17, 页码: -28
作者:
Tu, JJ
;
Li, ST
;
Chen, J
;
Song, YX
;
Fu, SB
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2018/08/24
Hybrid method to solve HP model on 3D lattice and to probe protein stability upon amino acid mutations
期刊论文
BMC SYSTEMS BIOLOGY, 2017, 卷号: 11, 页码: 13
作者:
Guo, Yuzhen
;
Tao, Fengying
;
Wu, Zikai
;
Wang, Yong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2018/07/30
Protein structure prediction
HP model
3D lattice
Particle swarm optimization
Protein stability
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