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科研机构
上海药物研究所 [9]
成都生物研究所 [3]
大连化学物理研究所 [3]
兰州理工大学 [2]
西北高原生物研究所 [1]
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期刊论文 [20]
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Integrated Transcriptomics and Reverse Pharmacophore Mapping-based Network Pharmacology to Explore the Mechanisms of Natural Compounds against Doxorubicin-induced Cardiotoxicity
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2022, 卷号: 25
作者:
Zhu, Junfeng
;
Yi, Xiaojiao
;
Ding, Haiying
;
Zhong, Like
;
Fang, Luo
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
Doxorubicin-induced cardiotoxicity
natural compounds
mechanism of action
gene expression profile
bioinformatics
network pharmacology
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Polygala tenuifolia-Acori tatarinowii herbal pair as an inspiration for substituted cinnamic α-asaronol esters: Design, synthesis, anticonvulsant activity, and inhibition of lactate dehydrogenase study
期刊论文
2019, 卷号: 183, 页码: 111650
作者:
Bai Yajun
;
He Xirui
;
Bai Yujun
;
Sun Ying
;
Zhao Zefeng
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2020/01/03
Anticonvulsant compounds
Combination of traditional Chinese medicine molecular chemistry
Lactate dehydrogenase inhibitor
Polygala tenuifolia-Acori tatarinowii herbal pair
Biological Activities of Artemisinin Derivatives Beyond Malaria
期刊论文
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 3, 页码: 205-222
作者:
Liu, Xiaoyan
;
Cao, Jianguo
;
Huang, Guozheng
;
Zhao, Qingjie
;
Shen, Jingshan
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
Anticancer activity
Antiviral activity
Artemisinin
Artemisinin derivatives
Dimer
Trimer
Reynoutria Japonica from Traditional Chinese Medicine: A Source of Competitive Adenosine Deaminase Inhibitors for Anticancer
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2019, 卷号: 22, 期号: 2, 页码: 113-122
作者:
Zhang, Xin-Guo
;
Ma, Guo-Yan
;
Fei Kou
;
Liu, Wen-Jie
;
Sun, Qiao-Yun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/15
ADA inhibitors
Reynoutria japonica
cordycepin
lymphoproliferative disorders
anti-cancer therapy
traditional chinese medicine
Reynoutria Japonica from Traditional Chinese Medicine: A Source of Competitive Adenosine Deaminase Inhibitors for Anticancer
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2019, 卷号: 22, 期号: 2, 页码: 113-122
作者:
Zhang, Xin-Guo
;
Ma, Guo-Yan
;
Fei Kou
;
Liu, Wen-Jie
;
Sun, Qiao-Yun
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2022/03/01
ADA inhibitors
Reynoutria japonica
cordycepin
lymphoproliferative disorders
anti-cancer therapy
traditional chinese medicine
Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells
期刊论文
HAEMATOLOGICA, 2018, 卷号: 103, 期号: 9, 页码: 1472-1483
作者:
Wu, Dang
;
Wang, Wanyan
;
Chen, Wuyan
;
Lian, Fulin
;
Lang, Li
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
A efficient method to identify cardioprotective components of Astragali Radix using a combination of molecularly imprinted polymers-based knockout extract and activity evaluation
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1576, 期号: 2018, 页码: 10-18
作者:
Xie, Jing
;
Xiong, Jing
;
Ding, Li-Sheng
;
Chen, Li
;
Zhou, Hua
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/10/29
Astragali Radix
Calycosin molecularly imprinted polymer
Chemical compounds' knockout
Hypoxia/reoxygenation model
Holistic evaluation
A efficient method to identify cardioprotective components of Astragali Radix using a combination of molecularly imprinted polymers-based knockout extract and activity evaluation
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1576, 期号: 2018, 页码: 10-18
作者:
Xie, Jing
;
Xiong, Jing
;
Ding, Li-Sheng
;
Chen, Li
;
Zhou, Hua
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/10/29
Astragali Radix
Calycosin molecularly imprinted polymer
Chemical compounds' knockout
Hypoxia/reoxygenation model
Holistic evaluation
Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 卷号: 18, 期号: 5
作者:
Huang, Qi
;
Wang, Ting
;
Yang, Liu
;
Wang, He-Yao
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
ginsenoside Rb2
NAFLD
type 2 diabetes
hepatosteatosis
autophagy
AMPK
sirt1
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